Search Results - "Roche, A C"

Bending and Unwinding of Nucleic Acid by Prion Protein by Bera, A, Roche, A-C, Nandi, P. K

“…Nucleic acid induces conformational changes in the prion protein (23−231 amino acids) to a structure resembling its pathological isoform. The prion protein, in…”
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Glycofection: facilitated gene transfer by cationic glycopolymers by Roche, A. C, Fajac, I, Grosse, S, Frison, N, Rondanino, C, Mayer, R, Monsigny, M

“…Mammalian cells express several types of lectins involved in intracellular trafficking, including endocytosis, interorganelle routing and putatively nuclear…”
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Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells by Midoux, Patrick, Mendes, Christina, Legrand, Alain, Raimond, Jacques, Mayer, Roger, Monsigny, Michel, Roche, Annie Claude

“…Plasmid DNA/glycosylated polylysine complexes were used to transfer in vitro a luciferase reporter gene into human hepatoma cells by a receptor-mediated…”
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ERGIC-53 is a functional mannose-selective and calcium-dependent human homologue of leguminous lectins by Itin, C, Roche, A C, Monsigny, M, Hauri, H P

“…Based on sequence homologies with leguminous lectins, the intermediate compartment marker ERGIC-53 was proposed to be a member of a putative new class of…”
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Enhanced biological activity of antisense oligonucleotides complexed with glycosylated poly-L-lysine by Stewart, A J, Pichon, C, Meunier, L, Midoux, P, Monsigny, M, Roche, A C

“…We sought to exploit glycosylated poly-L-lysine (pLK) to increase the uptake and biological antisense activity of a phosphorothioate oligonucleotide (pt-odn)…”
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Colorimetric determination of neutral sugars by a resorcinol sulfuric acid micromethod by Monsigny, M, Petit, C, Roche, A C

“…A microscale colorimetric assay for neutral sugars, in which neutral sugars react with resorcinol in the presence of 75% sulfuric acid solution is described…”
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Drug targeting: synthesis and endocytosis of oligonucleotide-neoglycoprotein conjugates by Bonfils, E., Depierreux, C., Midoux, P., Thuong, N.T., Monsigny, M., Roche, A. C.

“…Inhibition of gene expression by antisense oligonucleotides is limited by their low ability to enter cells. Knowing that sugar binding receptors, also called…”
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ERGIC-53, a Membrane Protein of the Endoplasmic Reticulum-Golgi Intermediate Compartment, Is Identical to MR60, an Intracellular Mannose-specific Lectin of Myelomonocytic Cells by Arar, C, Carpentier, V, Le Caer, J P, Monsigny, M, Legrand, A, Roche, A C

“…A mannose-specific membrane lectin (MR60) isolated from human myelomonocytic HL60 cells by affinity chromatography is expressed in intracellular organelles of…”
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Delivery of oligonucleotides into mammalian cells by anionic peptides: comparison between monomeric and dimeric peptides by Freulon, I, Roche, A C, Monsigny, M, Mayer, R

“…The use of antisense oligonucleotides as putative therapeutic agents is limited by their poor delivery into the cytosol and/or the nucleus because they are not…”
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Glycotargeting: The preparation of glyco-amino acids and derivatives from unprotected reducing sugars by Monsigny, M., Quétard, C., Bourgerie, S., Delay, D., Pichon, C., Midoux, P., Mayer, R., Roche, A.C.

“…▪ present on the surface of many cells. Many lectins actively recycle from membrane to endosomes and efficiently take up glycoconjugates in a sugar-dependent…”
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The nuclear export signal-dependent localization of oligonucleopeptides enhances the inhibition of the protein expression from a gene transcribed in cytosol by Meunier, L., Mayer, R., Monsigny, M., Roche, A. C.

“…Upon endocytosis, most oligodeoxynucleotides (ODNs) accumulate in vesicular compartments; a tiny number of them cross the vesicle membrane, reach the cytosol…”
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Optimized synthesis of phosphorothioate oligodeoxyribonucleotides substituted with a 5'-protected thiol function and a 3'-amino group by Aubert, Y, Bourgerie, S, Meunier, L, Mayer, R, Roche, A C, Monsigny, M, Thuong, N T, Asseline, U

“…A new deprotection procedure enables a medium scale preparation of phosphodiester and phosphor-othioate oligonucleotides substituted with a protected thiol…”
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Uptake of neoglycoproteins via membrane lectin(s) of L1210 cells evidenced by quantitative flow cytofluorometry and drug targeting by Monsigny, M, Roche, A C, Midoux, P

“…The presence and the sugar specificity of membrane lectins on the cell surface of mouse L1210 leukemia cells were demonstrated by using various…”
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The sugar binding activity of MR60, a mannose-specific shuttling lectin, requires a dimeric state by Carrière, Violaine, Piller, Véronique, Legrand, Alain, Monsigny, Michel, Roche, Annie-Claude

“…MR60 is an intracellular membrane protein which has been shown to act as a mannoside specific lectin and to be identical to ERGIC-53, a protein characteristic…”
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Pentoxifylline in toxic epidermal necrolysis and Stevens-Johnson syndrome by SANCLEMENTE, G, DE LA ROCHE, C. A, ESCOBAR, C. E, FALABELLA, R

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A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver by Akhurst, Barbara, Croager, Emma J., Farley-Roche, Caroline A., Ong, Jin Kar, Dumble, Melissa L., Knight, Belinda, Yeoh, George C.

“…Several reliable and reproducible methods are available to induce oval cells in rat liver. Effective methods often involve inhibiting proliferation in…”
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Antileishmanial drug targeting through glycosylated polymers specifically internalized by macrophage membrane lectins by NEGRE, E, CHANCE, M. L, HANBOULA, S. Y, MONSIGNY, M, ROCHE, A.-C, MAYER, R. M, HOMMEL, M

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Oligolysine-based oligosaccharide clusters: selective recognition and endocytosis by the mannose receptor and dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin by Frison, Natacha, Taylor, Maureen E, Soilleux, Elizabeth, Bousser, Marie-Thérèse, Mayer, Roger, Monsigny, Michel, Drickamer, Kurt, Roche, Annie-Claude

“…Dendritic cells are potent antigen-presenting cells that express several membrane lectins, including the mannose receptor and DC-SIGN (dendritic cell-specific…”
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Sugar-dependent nuclear import of glycoconjugates from the cytosol by Duverger, E, Carpentier, V, Roche, A C, Monsigny, M

“…Large proteins (above 40 kDa) do not migrate from the cytosol to the nucleus except when they contain or are substituted with specific peptides called nuclear…”
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Putative Role of Chloroquine in Gene Transfer into a Human Hepatoma Cell Line by DNA/Lactosylated Polylysine Complexes by Erbacher, Patrick, Roche, Annie Claude, Monsigny, Michel, Midoux, Patrick

“…Chloroquine improves drastically the transfection of cells upon exposure to plasmid DNA/glycosylated polylysine complexes. So far the mechanism of action of…”
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