Search Results - "Rocha Lima, Caio M S"

Full dose neoadjuvant FOLFIRINOX is associated with prolonged survival in patients with locally advanced pancreatic adenocarcinoma by Khushman, Moh'd, Dempsey, Naomi, Cudris Maldonado, Jennifer, Loaiza-Bonilla, Arturo, Velez, Michel, Carcas, Lauren, Dammrich, Daniel, Hurtado-Cordovi, Jorge, Parajuli, Ritesh, Pollack, Terri, Harwood, Ana P, Macintyre, Jessica, Tzeng, Ching-Wei D, Merchan, Jaime R, Restrepo, Maria H, Akunyili, Ikechukwu I, Ribeiro, Afonso, Narayanan, Govindarajan, Portelance, Lorraine, Sleeman, Danny, Levi, Joe U, Rocha Lima, Caio M.S, Hosein, Peter J

“…Abstract Background The efficacy of FOLFIRINOX for metastatic pancreatic cancer has led to its use in patients with earlier stages of disease. This study…”
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DNA damage repair deficiency as a predictive biomarker for FOLFIRINOX efficacy in metastatic pancreatic cancer by Palacio, Sofia, McMurry, Hannah S, Ali, Robert, Donenberg, Talia, Silva-Smith, Rachel, Wideroff, Gina, Sussman, Daniel A, Rocha Lima, Caio M S, Hosein, Peter J

“…Patients with pathogenic germline and somatic variants in DNA damage repair (DDR) genes may derive greater benefit with platinum-based chemotherapy in…”
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A phase I study of sequential administration of escalating doses of intravenous paclitaxel, oral topotecan, and fixed‐dose oral etoposide in patients with solid tumors by Rocha Lima, Caio M. S., Catapano, Carlo V., Pacheco, Daniel, Sherman, Carol A., Oakhill, Greg, Mushtaq, Chaudhry, Freeman, Kimberly D., Green, Mark R.

“…BACKGROUND Based on preclinical findings and on the clinical antitumor efficacy of sequential paclitaxel/topotecan and topotecan/etoposide, the authors sought…”
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Successful use of Trastuzumab with anthracycline-based chemotherapy followed by trastuzumab maintenance in patients with advanced HER2-positive gastric cancer by Palacio, Sofia, Loaiza-Bonilla, Arturo, Kittaneh, Muaiad, Kyriakopoulos, Christos, Ochoa, Roberto E, Escobar, Mauricio, Arango, Belisario, Restrepo, Maria H, Merchan, Jaime R, Rocha Lima, Caio M S R, Hosein, Peter J

“…There is no standard chemotherapy regimen that is universally accepted for the treatment of advanced gastric cancer. Trastuzumab added to chemotherapy improves…”
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Phase II trial of paclitaxel-topotecan-etoposide followed by consolidation chemoradiotherapy for limited-stage small cell lung cancer: CALGB 30002 by Miller, Antonius A, Wang, Xiaofei F, Bogart, Jeffrey A, Hodgson, Lydia D, Rocha Lima, Caio M S, Radford, James E, Vokes, Everett E, Green, Mark R

“…We sought to evaluate the activity and tolerance of the rationally designed sequence of paclitaxel-topotecan-etoposide, a nonplatinum regimen, as induction…”
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A Phase III open-label trial to evaluate efficacy and safety of CPI-613 plus modified FOLFIRINOX (mFFX) versus FOLFIRINOX (FFX) in patients with metastatic adenocarcinoma of the pancreas by Philip, Philip A, Buyse, Marc E, Alistar, Angela T, Rocha Lima, Caio MSPR, Luther, Sanjeev, Pardee, Timothy S, Van Cutsem, Eric

“…Devimistat (CPI-613 ) is a novel lipoate analog that inhibits the tricarboxcylic acid cycle at two key carbon entry points. Through its inhibition of pyruvate…”
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