Search Results - "Rocha E Silva, Luiz F"
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In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon
Published in Malaria journal (18-12-2015)“…The anti-malarials quinine and artemisinin were isolated from traditionally used plants (Cinchona spp. and Artemisia annua, respectively). The synthetic…”
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Antiplasmodial activity of synthetic ellipticine derivatives and an isolated analog
Published in Bioorganic & medicinal chemistry letters (15-06-2014)“…Novel and known ellipticine derivatives exhibit important in vitro inhibition of human malaria parasites. Ellipticine has been shown previously to exhibit…”
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Electrospun core/shell nanofibers as designed devices for efficient Artemisinin delivery
Published in European polymer journal (01-04-2017)“…[Display omitted] •Novel core–shell nanofibers for drug delivery are developed through electrospinning.•Artemisinin bioavailability is enhanced thanks to the…”
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Synthesis and antimalarial activity of quinones and structurally-related oxirane derivatives
Published in European journal of medicinal chemistry (27-01-2016)“…A series of eighteen quinones and structurally-related oxiranes were synthesized and evaluated for in vitro inhibitory activity against the…”
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In vitro and in vivo anti-malarial activity of limonoids isolated from the residual seed biomass from Carapa guianensis (andiroba) oil production
Published in Malaria journal (13-08-2014)“…Carapa guianensis is a cultivable tree used by traditional health practitioners in the Amazon region to treat several diseases and particularly symptoms…”
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In vitro and in vivo antimalarial activity of essential oils and chemical components from three medicinal plants found in northeastern Brazil
Published in Planta medica (01-05-2012)“…The prophylactic and therapeutic arsenal against malaria is quite restricted and all the antimalarials currently in use have limitations. Thus, there is a need…”
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