Search Results - "Rocha, Sura"

Effects of metformin on inflammation and short-term memory in streptozotocin-induced diabetic mice by de Oliveira, Wilma Helena, de Santana Nunes, Ana Karolina, de França, Maria Eduarda Rocha, dos Santos, Laise Aline, Lós, Deniele Bezerra, Santos Rocha, Sura Wanessa, de Sousa Barbosa, Karla Patrícia, Rodrigues, Gabriel Barros, Peixoto, Christina Alves

“…Abstract The aim of the present study was to analyze the action of metformin on short-term memory, glial cell activation and neuroinflammation caused by…”
Get full text

Metformin prevents p-tau and amyloid plaque deposition and memory impairment in diabetic mice by Oliveira, Wilma Helena, Braga, Clarissa Figueiredo, Lós, Deniele Bezerra, Araújo, Shyrlene Meiry Rocha, França, MariaEduarda Rocha, Duarte-Silva, Eduardo, Rodrigues, Gabriel Barros, Rocha, Sura Wanessa Santos, Peixoto, Christina Alves

“…Insulin deficiency or resistance can promote dementia and hallmarks of Alzheimer's disease (AD). The formation of neurofibrillary tangles of p-TAU protein,…”
Get full text

Zika virus replication in the mosquito Culex quinquefasciatus in Brazil by Guedes, Duschinka RD, Paiva, Marcelo HS, Donato, Mariana MA, Barbosa, Priscilla P, Krokovsky, Larissa, Rocha, Sura W dos S, Saraiva, Karina LA, Crespo, Mônica M, Rezende, Tatiana MT, Wallau, Gabriel L, Barbosa, Rosângela MR, Oliveira, Cláudia MF, Melo-Santos, Maria AV, Pena, Lindomar, Cordeiro, Marli T, Franca, Rafael F de O, Oliveira, André LS de, Peixoto, Christina A, Leal, Walter S, Ayres, Constância FJ

“…Zika virus (ZIKV) is a flavivirus that has recently been associated with an increased incidence of neonatal microcephaly and other neurological disorders. The…”
Get full text

Involvement of AMPK, IKβα-NFκB and eNOS in the sildenafil anti-inflammatory mechanism in a demyelination model by Nunes, Ana Karolina Santana, Rapôso, Catarina, Rocha, Sura Wanessa Santos, Barbosa, Karla Patrícia de Sousa, de Almeida Luna, Rayana Leal, da Cruz-Höfling, Maria Alice, Peixoto, Christina Alves

“…Abstract Sildenafil (Viagra®) has recently been found to have a neuroprotective effect, which occurs through the inhibition of inflammation and demyelination…”
Get full text

Liver expression of IL-22, IL-22R1 and IL-22BP in patients with chronic hepatitis C with different fibrosis stages by de Brito, Rodrigo José Videres Cordeiro, do Carmo, Rodrigo Feliciano, Silva, Bruna Manuella Souza, Costa, Ana Clara Santos, Rocha, Sura Wanessa Santos, Vasconcelos, Luydson Richardson Silva, Pereira, Leila Maria Moreira Beltrão, de Moura, Patrícia Muniz Mendes Freire

“…•Liver biopsies at stage F1 to F3 expressed more IL-22 than F0 or F4.•The number of cells expressing IL-22R1 decreased as fibrosis increased.•There was an…”
Get full text

Preventive role of metformin on peripheral neuropathy induced by diabetes by Lós, Deniele Bezerra, Oliveira, Wilma Helena de, Duarte-Silva, Eduardo, Sougey, Wenddy Wyllie Damascena, Freitas, Elvis da Silva Rodrigues de, de Oliveira, Anne Gabrielle Vasconcelos, Braga, Clarissa Figueredo, França, Maria Eduarda Rocha de, Araújo, Shyrlene Meiry da Rocha, Rodrigues, Gabriel Barros, Rocha, Sura Wanessa Santos, Peixoto, Christina Alves, Moraes, Silvia Regina Arruda de

“…Metformin is the first line drug in the treatment of type 2 diabetes, however, little is known about its therapeutic potential to prevent or delay damage to…”
Get full text

New thiazolidinedione LPSF/GQ-2 inhibits NFκB and MAPK activation in LPS-induced acute lung inflammation by Santos, Laise Aline Martins dos, Rodrigues, Gabriel Barros, Mota, Fernanda Virgínia Barreto, França, Maria Eduarda Rocha de, de Souza Barbosa, Karla Patrícia, Oliveira, Wilma Helena de, Rocha, Sura Wanessa Santos, Lós, Deniele Bezerra, Silva, Amanda Karolina Soares, Silva, Teresinha Gonçalves da, Peixoto, Christina Alves

“…Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are responsible for high mortality rates in critical patients. Despite >50 years of…”
Get full text

Induction of cancer cell stemness by depletion of macrohistone H2A1 in hepatocellular carcinoma by Lo Re, Oriana, Fusilli, Caterina, Rappa, Francesca, Van Haele, Matthias, Douet, Julien, Pindjakova, Jana, Rocha, Sura Wanessa, Pata, Illar, Valčíková, Barbora, Uldrijan, Stjepan, Yeung, Raymond S., Peixoto, Christina Alves, Roskams, Tania, Buschbeck, Marcus, Mazza, Tommaso, Vinciguerra, Manlio

“…Hepatocellular carcinomas (HCC) contain a subpopulation of cancer stem cells (CSCs), which exhibit stem cell–like features and are responsible for tumor…”
Get full text

Reduction of carrageenan-induced acute pulmonary inflammation in mice by novel thiazolidinedione derivative LPSF/RA-4 by Barbosa, Karla P.S., Santos, Laise A.M., Ribeiro, Edlene L., Fragoso, Ingrid T., Rocha, Sura W.S., Nunes, Ana K.S., França, Maria E.R., Silva, Bruna S., Silva, Amanda K.S.e., Donato, Mariana A.M., Gomes, Fabiana O.S., Silva, Teresinha G., Pitta, Ivan R., Pitta, Marina R., Lima, Maria C.A., Uchôa, Flávia D.T., Galdino, Suely L., Peixoto, Christina A.

“…A number of studies have demonstrated the biological activities of peroxisome proliferator-activated receptors. However, few studies have addressed the effects…”
Get full text

Effect of the combination of metformin hydrochloride and melatonin on oxidative stress before and during pregnancy, and biochemical and histopathological analysis of the livers of rats after treatment for polycystic ovary syndrome by Lemos, Ana Janaina Jeanine M., Peixoto, Christina A., Teixeira, Álvaro Aguiar C., Luna, Rayana Leal A., Rocha, Sura Wanessa S., Santos, Hilda Michelly P., Silva, Amanda Karolina S., Nunes, Ana Karolina S., Wanderley-Teixeira, Valéria

“…The aim of the present study was to analyze the effect of a combination of metformin hydrochloride and melatonin on oxidative stress together with a…”
Get full text

Diethylcarbamazine attenuates the expression of pro-fibrogenic markers and hepatic stellate cells activation in carbon tetrachloride-induced liver fibrosis by França, Maria Eduarda Rocha de, Rocha, Sura Wanessa Santos, Oliveira, Wilma Helena, Santos, Laise Aline, de Oliveira, Anne Gabrielle Vasconcelos, Barbosa, Karla Patrícia Sousa, Nunes, Ana Karolina Santana, Rodrigues, Gabriel Barros, Lós, Deniele Bezerra, Peixoto, Christina Alves

“…Background and aim While diethylcarbamazine citrate (DEC) displays important anti-inflammatory effects in experimental models of liver injury, the mechanisms…”
Get full text

Diethylcarbamazine Reduces Chronic Inflammation and Fibrosis in Carbon Tetrachloride- (CCl_4^-) Induced Liver Injury in Mice by Peixoto, Christina Alves, Luna, Rayana Leal de Almeida, de Oliveira, Anne Gabrielle Vasconcelos, Pastor, André Filipe, Nunes, Ana Karolina de Santana, Barbosa, Karla Patricia de Souza, Rodrigues, Gabriel Barros, França, Maria Eduarda Rocha de, Rocha, Sura Wanessa Santos, Oliveira, Wilma Helena

“…This study investigated the anti-inflammatory effects of DEC on the CCl4-induced hepatotoxicity in C57BL/6 mice. Chronic inflammation was induced by i.p…”
Get full text

Inhibition of NF-κB activation by diethylcarbamazine prevents alcohol-induced liver injury in C57BL/6 mice by da Silva, Bruna Santos, Rodrigues, Gabriel Barros, Rocha, Sura Wanessa Santos, Ribeiro, Edlene Lima, Gomes, Fabiana Oliveira dos Santos, e Silva, Amanda Karolina Soares, Peixoto, Christina Alves

“…Graphical abstract…”
Get full text

Diethylcarbamazine inhibits NF-κB activation in acute lung injury induced by carrageenan in mice by Santos, Laise Aline Martins, Ribeiro, Edlene Lima, Barbosa, Karla Patrícia Sousa, Fragoso, Ingrid Tavares, Gomes, Fabiana Oliveira dos Santos, Donato, Mariana Aragão Matos, Silva, Bruna Santos, Silva, Amanda Karolina Soares, Rocha, Sura Wanessa Santos, França, Maria Eduarda Rocha, Rodrigues, Gabriel Barros, Silva, Teresinha Gonçalves, Peixoto, Christina Alves

“…Diethylcarbamazine citrate (DEC) is widely used to treat lymphatic filariasis and Tropical Pulmonary Eosinophilia. A number of studies have reported a possible…”
Get full text

Diethylcarbamazine: Possible therapeutic alternative in the treatment of alcoholic liver disease in C57BL/6 mice by Rodrigues, Gabriel Barros, Rocha, Sura Wanessa Santos, Santos, Laise Aline Martins dos, de Oliveira, Wilma Helena, Gomes, Fabiana Oliveira dos Santos, de França, Maria Eduarda da Rocha, Lós, Deniele Bezerra, Peixoto, Christina Alves

“…Summary Alcoholic liver disease is a major cause of chronic liver disease worldwide. Diethylcarbamazine (DEC) is a drug that has anti‐inflammatory properties…”
Get full text

Diethylcarbamazine Attenuates the Development of Carrageenan-Induced Lung Injury in Mice by Peixoto, Christina Alves, Amaro da Silva Junior, Valdemiro, Silva, Amanda Karolina Soares e, Silva, Bruna Santos da, Oliveira dos Santos Gomes, Fabiana, Donato, Mariana Aragão Matos, Fragoso, Ingrid Tavares, Barbosa, Karla Patricia de Souza, Ribeiro, Edlene Lima, Rocha, Sura Wanessa Santos

“…Diethylcarbamazine (DEC) is an antifilarial drug with potent anti-inflammatory properties as a result of its interference with the metabolism of arachidonic…”
Get full text

Chronic treatment with Sildenafil has no effect on folliculogenesis or fertility in C57BL/6 and C57BL/6 knockout for iNOS mice by Donato, Mariana Aragão Matos, Ribeiro, Edlene Lima, Torres, Dilênia de Oliveira Cipriano, Soares e Silva, Amanda Karolina, dos Santos Gomes, Fabiana Oliveira, Santos e Silva, Bruna, Rocha, Sura Wanessa Santos, Peixoto, Christina Alves

“…Graphical abstract…”
Get full text

Effect of chronic Sildenafil treatment on the prostate of C57Bl/6 mice by Gomes, Fabiana Oliveira dos Santos, Carvalho, Maria da Conceição, Saraiva, Karina Lidianne Alcântara, Ribeiro, Edlene Lima, e Silva, Amanda Karolina Soares, Donato, Mariana Aragão Matos, Rocha, Sura Wanessa Santos, e Silva, Bruna Santos, Peixoto, Christina Alves

“…Graphical abstract…”
Get full text

Response to: 'Lack of evidence for Zika virus transmission by Culex mosquitoes' by Ayres, Constância, Guedes, Duschinka, Paiva, Marcelo, Donato, Mariana, Barbosa, Priscilla, Krokovsky, Larissa, Rocha, Sura, Saraiva, Karina, Crespo, Mônica, Rezende, Tatiana, Wallau, Gabriel, Barbosa, Rosângela, Oliveira, Cláudia, Melo-Santos, Maria Alice, Pena, Lindomar, Cordeiro, Marli, Franca, Rafael, Oliveira, André, Peixoto, Christina, Leal, Walter S

“…Emerging Microbes & Infections (2017) 6, e91; doi: 10.1038/emi.2017.86 ; published online 18 October 2017…”
Get full text

Student Mobility and Research Capacity: A Global Health Experience by Campos, Letícia Nunes, Rocha, Sura Wanessa Santos

“…Global South countries struggle to train and retain researchers and practitioners to address local, regional, and global health challenges. Therefore, it is…”
Get full text