Search Results - "Rocha, Marcio S"

Caffeine Enhances the Toxicity of Platinum-Based Drugs at the Molecular Level Even Outside of the Intracellular Environment: A Single-Molecule Force Spectroscopy Study by de Oliveira, Rayane M, Moura, Tiago A, Rocha, Márcio S

“…It is well reported in the literature that caffeine, the most consumed alkaloid around the world, enhances the anticancer effects of the drug cisplatin by…”
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Mechanism of DNA Intercalation by Chloroquine Provides Insights into Toxicity by Joshi, Joha, McCauley, Micah J, Morse, Michael, Muccio, Michael R, Kanlong, Joseph G, Rocha, Márcio S, Rouzina, Ioulia, Musier-Forsyth, Karin, Williams, Mark C

“…Chloroquine has been used as a potent antimalarial, anticancer drug, and prophylactic. While chloroquine is known to interact with DNA, the details of…”
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New Insights into the Mechanism of Action of the Drug Chloroquine: Direct Interaction with DNA and Cytotoxicity by Costa, Ethe A., Gonçalves, Amanda P., Batista, Josiane A. D., Bazoni, Raniella F., Santos, Anésia A., Rocha, Márcio S.

“…Chloroquine (CLQ) and hydroxychloroquine (HCLQ) are compounds largely employed in the treatment of various human diseases for decades. Nevertheless, a number…”
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Revisiting the neighbor exclusion model and its applications by Rocha, Marcio S.

“…We review the neighbor exclusion model and some of its applications to analyze the binding data of DNA‐ligand complexes. We revisit the closed form of the…”
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Optical Trapping and Manipulation of Superparamagnetic Beads Using Annular-Shaped Beams by Oliveira, Leandro, Campos, Warlley, Rocha, Marcio

“…We propose an optical tweezers setup based on an annular-shaped laser beam that is efficient to trap 2.8 μ m-diameter superparamagnetic particles. The optical…”
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New antineoplastic agent based on a dibenzoylmethane derivative: Cytotoxic effect and direct interaction with DNA by Nascimento, Fernanda R., Moura, Tiago A., Baeta, Jefferson V.P.B., Publio, Bruno C., Ferreira, Pollyanna M.F., Santos, Anésia A., França, Andressa A.P., Rocha, Marcio S., Diaz-Muñoz, Gaspar, Diaz, Marisa A.N.

“…Melanoma accounts for only 4% of all skin cancers but is among the most lethal cutaneous neoplasms. Dacarbazine is the drug of choice for the treatment of…”
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Use of Organic Semiconductors as Handles for Optical Tweezers Experiments: Trapping and Manipulating Polyaniline (PANI) Microparticles by Oliveira, Kairon M., Moura, Tiago A., Lucas, Janaísa L. C., Teixeira, Alvaro V. N. C., Rocha, Márcio S., Mendes, Joaquim B. S.

“…Here we propose the use of the organic semiconductor polyaniline (PANI) for the preparation of spherical-shaped microparticles to serve as handles in optical…”
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Normal and tumoral melanocytes exhibit q-Gaussian random search patterns by da Silva, Priscila C A, Rosembach, Tiago V, Santos, Anésia A, Rocha, Márcio S, Martins, Marcelo L

“…In multicellular organisms, cell motility is central in all morphogenetic processes, tissue maintenance, wound healing and immune surveillance. Hence, failures…”
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Isolation, characterization and evaluation of antimicrobial and cytotoxic activity of estragole, obtained from the essential oil of Croton zehntneri (Euphorbiaceae) by Andrade, Thallita C B, De Lima, Sidney G, Freitas, Rivelilson M, Rocha, Márcio S, Islam, Torequl, Da Silva, Teresinha G, Militão, Gardenia C G

“…Croton zehntneri (Euphorbiaceae) is a native aromatic plant from Northeast region of Brazil. The monoterpenoid estragole (ESL) has been isolated by classical…”
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Gas Chromatography-Triple Quadrupole Mass Spectrometry Analysis and Vasorelaxant Effect of Essential Oil from Protium heptaphyllum (Aubl.) March. by Costa, José Galberto Martins da, Melhem, Marcia S. C., Mendes, Marcelo B., Pereira de Oliveira, Aldeídia, Rocha, Márcio S., Silva Filho, José C., Almeida, Lorena T. G., de Lima, Sidney Gonçalo, Mobin, Mitra, Carvalho, Fernando Aécio de Amorim

“…The Protium heptaphyllum species, also known as Almécega, produces an oily resin, used in folk medicine as an analgesic and anti-inflammatory agent, in…”
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Characterization of the inclusion complex of the essential oil of Lantana camara L. and β-cyclodextrin by vibrational spectroscopy, GC–MS, and X-ray diffraction by Rocha, Márcio dos S., de Lima, Sidney G., Viana, Bartolomeu C., Costa, José Galberto Martins, Santos, Francisco E. P.

“…The genus Lantana is widely used in folk medicine because its essential oil has antibacterial, antifungal and repellent activity. However, its thermal…”
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New tools to study biophysical properties of single molecules and single cells by Rocha, Márcio S, Mesquita, Oscar N

“…We present a review on two new tools to study biophysical properties of single molecules and single cells. A laser incident through a high numerical aperture…”
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Aliphatic and aromatic biomarkers of the Devonian source rocks from the Western Parnaíba Basin Brazil: Pimenteiras Formation by de Sousa, Alek A.C., Sousa, Edymilaís S., Rocha, Márcio S., Sousa Junior, Gustavo R., de Souza, Igor V.A.F., Brito, Ailton S., Souza, Alexandre A., Lopes, José A.D., Nogueira, Afonso C.R., de Lima, Sidney G.

“…Previous geochemical studies carried out in the Parnaíba Basin (Brazil) show that natural gas deposits, whose source rock is formed by the shales of the…”
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Allyl Dibenzoylmethane Derivative: Antimelanoma Activity and Study of Its Molecular Mechanism of Interaction with DNA by Baeta, Jefferson, Andrade, Ulisses, Oliveira, Rayane, Oliveira, Leandro, Santos, Anésia, Diaz-Muñoz, Gaspar, Rocha, Márcio, Diaz, Marisa

“…In this study, we assessed the cytotoxic effect of 1,3-diphenyl-2-allyl-1,3-propanedione (DPAP) on B16F10 and Tm5 melanoma cells and investigated its…”
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Theoretical and Experimental Investigations on Inclusion Complex β-Cyclodextrin and Sulcatone: A Cardiovascular Activity Evaluation by Silva, Ivan, Feitosa, Eduardo, Santos, Márcio, Silva, Raiane, Rocha, Márcio, da Silva, Francisco, Lima, Francisco, Costa, Ana Maria, Alves, Péricles, de Sousa, Samuel, Oliveira, Aldeídia, de Lima, Sidney

“…In this paper, we have applied state-of-the-art technologies and new investigations were developed focusing on obtaining simple and inexpensive molecules for…”
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Inclusion complex of 2-phenylethanol in β-cyclodextrin: Preparation, characterization, computational study and evaluation of antinociceptive activity by Silva, Raiane M., de Araújo, Moises P., Piauilino, Celyane A., Rocha, Márcio dos S., Silva, Ivan dos S., da Silva, Francisco I., Lima, Francisco das C.A., Almeida, Fernanda R.de C., Meneses, Allan K.S., de Sousa, Samuel A.A., de Lima, Sidney G.

“…•Preparation of an inclusion complex between β-cyclodextrin and 2-phenylethanol.•Characterization of inclusion complex using techniques such as XRD, TGA, DSC,…”
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Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying by Sousa, Antônio, Oliveira, George, Fonseca, Lorenna, Rocha, Marcio, Rai, Mahendra, Santos, Francisco, de Lima, Sidney

“…Croton zehntneri Pax et Hoffm. is a plant from Northeastern Brazil, whose main component of its essential oil is estragole. Its thermal instability and low…”
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Preparação e caracterização do complexo de inclusão do óleo essencial de Croton zehntneri com β-ciclodextrina by Aguiar, Ulisses N., Lima, Sidney G. de, Rocha, Márcio S., Freitas, Rivelilson Mendes de, Oliveira, Talita M., Silva, Raiane M., Moura, Lara C. B., Almeida, Lorena T. G. de

“…Croton zehntneri, a plant native to northeastern Brazil, is widely used in folk medicine to treat gastrointestinal problems and has rich essential oil content…”
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Obtaining Quantitative Parameters of DNA-Ligand Cooperative Binding from Persistence Length Measurements by Siman, Livia, Carrasco, Ismael S.S., da Silva, Jafferson K.L., Oliveira, Maria Cristina, Rocha, Marcio S., Mesquita, Oscar N.

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Chemical constituents and evaluation of cytotoxic and antifungal activity of Lantana camara essential oils by Medeiros, Lídia B. P., Rocha, Márcio dos S., Lima, Sidney G. de, Sousa Júnior, Gustavo R. de, Citó, Antônia M. das G. L., Silva, Davi da, Lopes, José A. D., Moura, Dinara J., Saffi, Jenifer, Mobin, Mitra, Costa, José G.M. da

“…The essential oil (EO) of aerial parts of Lantana camara L., Verbenaceae, from Simões, Piaui, Northeast of Brazil, were obtained by hydrodistillation and…”
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