Search Results - "Rocha, José J.R."
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A Novel Severity Score Index for Febrile Neutropenic Patients with Colorectal Diseases
Published in Gastroenterology research and practice (01-01-2019)“…Introduction. Abdominal and anorectal disorders may be the cause of clinical decompensation in neutropenic febrile patients, particularly those with…”
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Infliximab Trough Levels and Quality of Life in Patients with Inflammatory Bowel Disease in Maintenance Therapy
Published in Gastroenterology research and practice (01-01-2018)“…Objective. Investigate the association between infliximab trough levels and quality of life in inflammatory bowel disease patients in maintenance therapy…”
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Acetylcholine, Fatty Acids, and Lipid Mediators Are Linked to COVID-19 Severity
Published in The Journal of immunology (1950) (15-07-2022)“…Lipid and cholinergic mediators are inflammatory regulators, but their role in the immunopathology of COVID-19 is still unclear. Here, we used human blood and…”
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Divergent androgenic modulation of SARS-CoV-2 infection cooperates with dysregulated immune response to dictate worse COVID-19 outcomes in men
Published in Brain, behavior, and immunity (01-11-2023)“…•Lowering testosterone is a hallmark of the worst COVID-19 prognosis in men.•Reduced testosterone in men with COVID-19 is partially dependent on age and…”
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sTREM-1 Predicts Disease Severity and Mortality in COVID-19 Patients: Involvement of Peripheral Blood Leukocytes and MMP-8 Activity
Published in Viruses (15-12-2021)“…Uncontrolled inflammatory responses play a critical role in coronavirus disease (COVID-19). In this context, because the triggering-receptor expressed on…”
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The turning point of COVID‐19 severity is associated with a unique circulating neutrophil gene signature
Published in Immunology (01-07-2023)“…COVID‐19 has a broad spectrum of clinical manifestations associated with the host immune response heterogeneity. Despite the advances in COVID‐19 research, it…”
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Matrix Metalloproteinases on Severe COVID-19 Lung Disease Pathogenesis: Cooperative Actions of MMP-8/MMP-2 Axis on Immune Response through HLA-G Shedding and Oxidative Stress
Published in Biomolecules (Basel, Switzerland) (19-04-2022)“…Patients with COVID-19 predominantly have a respiratory tract infection and acute lung failure is the most severe complication. While the molecular basis of…”
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The Interplay among Glucocorticoid Therapy, Platelet-Activating Factor and Endocannabinoid Release Influences the Inflammatory Response to COVID-19
Published in Viruses (01-02-2023)“…COVID-19 is associated with a dysregulated immune response. Currently, several medicines are licensed for the treatment of this disease. Due to their…”
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Adjunctive Hyperbaric Oxygen Therapy in Refractory Crohn’s Disease: An Observational Study
Published in Gastroenterology research and practice (2021)“…Background and Aims. Patients may experience complications of Crohn’s disease (CD) even when treated with optimal medical therapy strategies. Previous data…”
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Hyperbaric oxygen therapy ameliorates TNBS-induced acute distal colitis in rats
Published in Medical gas research (16-04-2015)“…This study investigated the therapeutic effects of hyperbaric oxygen in experimental acute distal colitis focusing on its effect on the production of…”
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Hyperbaric oxygen therapy reduces COX-2 expression in a dimethylhydrazine-induced rat model of colorectal carcinogenesis
Published in Undersea & hyperbaric medicine (01-05-2012)“…A better understanding of oncogenesis mechanisms should result in more effective approaches to colorectal cancer (CRC) treatment and prevention. Hyperbaric…”
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Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil
Published in World journal of gastroenterology : WJG (14-10-2019)“…Inflammatory bowel diseases (IBD) have been associated with a low quality of life (QoL) and a negative impact on work productivity compared to the general…”
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Real-world disease activity and sociodemographic, clinical and treatment characteristics of moderate-to-severe inflammatory bowel disease in Brazil
Published in World journal of gastroenterology : WJG (14-01-2021)“…Understanding the treatment landscape of inflammatory bowel diseases (IBD) is essential for improving disease management and patient outcomes. Brazil is the…”
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Real-world treatment patterns and disease control over one year in patients with inflammatory bowel disease in Brazil
Published in World journal of gastroenterology : WJG (21-06-2021)“…BACKGROUNDCrohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBDs) with a remission-relapsing presentation and symptomatic…”
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