Search Results - "Rocha, Danilo D."

Structure–Activity Relationships for Withanolides as Inducers of the Cellular Heat-Shock Response by Wijeratne, E. M. Kithsiri, Xu, Ya-Ming, Scherz-Shouval, Ruth, Marron, Marilyn T, Rocha, Danilo D, Liu, Manping X, Costa-Lotufo, Leticia V, Santagata, Sandro, Lindquist, Susan, Whitesell, Luke, Gunatilaka, A. A. Leslie

“…To understand the relationship between the structure and the remarkably diverse bioactivities reported for withanolides, we obtained withaferin A (WA; 1) and…”
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Tropane alkaloids from the stem bark of Erythroxylum bezerrae by Brito, Luana San de O., Pinto, Francisco das Chagas L., de Filho, Manoel Odorico M., Rocha, Danilo D., Mendoza, Maria Fernanda M., Ayala, Alejandro Pedro, Bezerra, Beatriz Pinheiro, Loiola, Maria Iracema B., Canuto, Kirley M., Silveira, Edilberto R., Pessoa, Otilia Deusdenia L.

“…Six previously undescribed tropane alkaloids, designated as erythrobezerrines A-F, were isolated from the EtOH extract from the stem bark of Erythroxylum…”
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Effect of EGF on expression and localization of maturation‐promoting factor, mitogen‐activated protein kinase, p34cdc2 and cyclin B during different culture periods on in vitro maturation of canine oocytes by Pereira, Leda Maria C., Bersano, Paulo Ricardo O., Rocha, Danilo D., Lopes, Maria Denise

“…Contents This study aimed to investigate the localization of MPF, MAPK, p34cdc2 and cyclin B1 proteins, before and after treatment with EGF during different…”
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Effect of EGF on expression and localization of maturation-promoting factor, mitogen-activated protein kinase, p34 cdc2 and cyclin B during different culture periods on in vitro maturation of canine oocytes by Pereira, Leda Maria C, Bersano, Paulo Ricardo O, Rocha, Danilo D, Lopes, Maria Denise

“…This study aimed to investigate the localization of MPF, MAPK, p34 and cyclin B1 proteins, before and after treatment with EGF during different moments of…”
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Ritterostatin GN1N, a Cephalostatin–Ritterazine Bis‐steroidal Pyrazine Hybrid, Selectively Targets GRP78 by Ambrose, Andrew J., Santos, Evelyne A., Jimenez, Paula C., Rocha, Danilo D., Wilke, Diego V., Beuzer, Paolo, Axelrod, Josh, Kumar Kanduluru, Ananda, Fuchs, Philip L., Cang, Hu, Costa‐Lotufo, Letícia V., Chapman, Eli, La Clair, James J.

“…Natural products discovered by using agnostic approaches, unlike rationally designed leads or those obtained through high‐throughput screening, offer the…”
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Fluorescent kapakahines serve as non-toxic probes for live cell Golgi imaging by Rocha, Danilo D., Espejo, Vinson R., Rainier, Jon D., La Clair, James J., Costa-Lotufo, Letícia V.

“…There is an ongoing need for fluorescent probes that specifically-target select organelles within mammalian cells. This study describes the development of…”
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Geopyxins A–E, ent-Kaurane Diterpenoids from Endolichenic Fungal Strains Geopyxis aff. majalis and Geopyxis sp. AZ0066: Structure–Activity Relationships of Geopyxins and Their Analogues by Wijeratne, E. M. Kithsiri, Bashyal, Bharat P, Liu, Manping X, Rocha, Danilo D, Gunaherath, G. M. Kamal B, U’Ren, Jana M, Gunatilaka, Malkanthi K, Arnold, A. Elizabeth, Whitesell, Luke, Gunatilaka, A. A. Leslie

“…Four new ent-kaurane diterpenoids, geopyxins A–D (1–4), were isolated from Geopyxis aff. majalis, a fungus occurring in the lichen Pseudevernia intensa,…”
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Withanolides from leaves of cultivated Acnistus arborescens by Batista, Pedro Henrique J., de Lima, Karísia Sousa B., Pinto, Francisco das Chagas L., Tavares, Juliane L., de A. Uchoa, Daniel E., Costa-Lotufo, Letícia V., Rocha, Danilo D., Silveira, Edilberto R., Bezerra, Antonio Marcos E., Canuto, Kirley M., Pessoa, Otília Deusdenia L.

“…Seven withanolides, including four previously unknown, were isolated from the acetone and ethanol extracts of cultivated specimens of Acnistus arborescens…”
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The Hybrid Pyrroloisoindolone-Dehydropyrrolizine Alkaloid (−)-Chlorizidine A Targets Proteins within the Glycolytic Pathway by Álvarez-Micó, Xavier, Rocha, Danilo D., Guimarães, Larissa A., Ambrose, Andrew, Chapman, Eli, Costa-Lotufo, Leticia V., La Clair, James J., Fenical, William

“…The cytotoxic activity of (−)‐chlorizidine A, a marine alkaloid containing a unique fusion between a pyrroloisoindolone and dehydropyrrolizine, was explored by…”
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Studies on the Cytotoxicity of Miscellaneous Compounds from Eupatorium betonicaeforme (D.C.) Baker (Asteraceae) by Rocha, Danilo D., Dantas, Ivana N. F., Albuquerque, Maria Rose Jane R., Montenegro, Raquel C., Pessoa, Cláudia, de Moraes, Manoel Odorico, Pessoa, Otília Deusdênia L., Silveira, Edilberto R., Costa-Lotufo, Letícia V.

“…A detailed study on the cytotoxic effects of five known constituents isolated from the flowers and roots of Eupatorium betonicaeforme is reported, including…”
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Cytotoxic Plakortides from the Brazilian Marine Sponge Plakortis angulospiculatus by Santos, Evelyne A, Quintela, Amanda L, Ferreira, Elthon G, Sousa, Thiciana S, Pinto, Francisco das Chagas L, Hajdu, Eduardo, Carvalho, Mariana S, Salani, Sula, Rocha, Danilo D, Wilke, Diego V, Torres, Maria da Conceição M, Jimenez, Paula C, Silveira, Edilberto R, La Clair, James J, Pessoa, Otília Deusdênia L, Costa-Lotufo, Letícia V

“…Three new plakortides, 7,8-dihydroplakortide E (1), 2, and 10, along with known natural products 3, 4, spongosoritin A (5), 6–8, and plakortide P (9), were…”
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Ritterostatin G N 1 N , a Cephalostatin-Ritterazine Bis-steroidal Pyrazine Hybrid, Selectively Targets GRP78 by Ambrose, Andrew J, Santos, Evelyne A, Jimenez, Paula C, Rocha, Danilo D, Wilke, Diego V, Beuzer, Paolo, Axelrod, Josh, Kumar Kanduluru, Ananda, Fuchs, Philip L, Cang, Hu, Costa-Lotufo, Letícia V, Chapman, Eli, La Clair, James J

“…Natural products discovered by using agnostic approaches, unlike rationally designed leads or those obtained through high-throughput screening, offer the…”
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Genetic toxicology evaluation of essential oil of Alpinia zerumbet and its chemoprotective effects against H2O2-induced DNA damage in cultured human leukocytes by Cavalcanti, Bruno C., Ferreira, José R.O., Cabral, Igor O., Magalhães, Hemerson I.F., de Oliveira, Cecília C., Rodrigues, Felipe A.R., Rocha, Danilo D., Barros, Francisco W.A., da Silva, Cecília R., Júnior, Hélio V.N., Canuto, Kirley M., Silveira, Edilberto R., Pessoa, Cláudia, Moraes, Manoel O.

“…► Essential oil (EO) of Alpinia zerumbet did not induce genetic toxicity in human leukocytes. ► EO did not exert any mutagenic effects on peripheral blood…”
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Identification of Pyrroloformamide as a Cytokinesis Modulator by Abreu, Paula A., Sousa, Thiciana S., Jimenez, Paula C., Wilke, Diego V., Rocha, Danilo D., Freitas, Hozana P. S., Pessoa, Otília D. L., La Clair, James J., Costa-Lotufo, Letícia V.

“…Discovered in the late 1940s, the pyrrolinonodithioles represent a family of potent disulfide‐containing natural products. Although they are understood in a…”
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Cell cycle arrest through inhibition of tubulin polymerization by withaphysalin F, a bioactive compound isolated from Acnistus arborescens by Rocha, Danilo D., Balgi, Aruna, Maia, Ana Isabel V., Pessoa, Otilia D., Silveira, Edilberto R., Costa-Lotufo, Letícia V., Roberge, Michel, Pessoa, Claudia

“…Summary Many compounds used in the treatment of cancer possess tubulin-interacting properties that lead to mitotic arrest. Withaphysalins are potent cytotoxic…”
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Exergoenvironmental analysis for evaluating coal-fired power plants technologies by Rocha, Danilo H.D., Siqueira, Diana S., Silva, Rogério J.

“…Coal is a source of fundamental importance for the global electrical matrix due to its massive use, its abundance, worldwide distribution, low price, and etc…”
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Exergoenvironmental analysis of a ultra-supercritical coal-fired power plant by Rocha, Danilo H.D., Silva, Rogério J.

“…This paper presents an exergoenvironmental analysis for a coal-fired ultra-supercritical technology. The study was carried out for a generating unit of 800 MWe…”
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Ritterostatin G sub(N)1 sub(N), a Cephalostatin-Ritterazine Bis-steroidal Pyrazine Hybrid, Selectively Targets GRP78 by Ambrose, Andrew J, Santos, Evelyne A, Jimenez, Paula C, Rocha, Danilo D, Wilke, Diego V, Beuzer, Paolo, Axelrod, Josh, KumarKanduluru, Ananda, Fuchs, Philip L, Cang, Hu, Costa-Lotufo, Leticia V, Chapman, Eli, LaClair, James J

“…Natural products discovered by using agnostic approaches, unlike rationally designed leads or those obtained through high-throughput screening, offer the…”
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The Hybrid Pyrroloisoindolone-Dehydropyrrolizine Alkaloid (-)-ChlorizidineA Targets Proteins within the Glycolytic Pathway by Alvarez-Mico, Xavier, Rocha, Danilo D, Guimaraes, Larissa A, Ambrose, Andrew, Chapman, Eli, Costa-Lotufo, Leticia V, LaClair, James J, Fenical, William

“…The cytotoxic activity of (-)-chlorizidineA, a marine alkaloid containing a unique fusion between a pyrroloisoindolone and dehydropyrrolizine, was explored by…”
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Cytotoxic Alkaloids from Hippeastrum solandriflorum Lindl by Carvalho, Kaline R., Silva, Alison B., Torres, Maria Conceição M., Pinto, Francisco Chagas L., Guimarães, Larissa A., Rocha, Danilo D., Silveira, Edilberto R., Costa-Lotufo, Letícia V., Braz-Filho, Raimundo, Pessoa, Otília Deusdênia. L.

“…One new alkaloid, 2α-10bα-dihydroxy-9-O-demethylhomolycorine, in addition to seven others known alkaloids, and 5-(hydroxymethyl)furfural, piscidic acid and…”
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