Search Results - "Rocconi, Rodney P."
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ALDH1A1 maintains ovarian cancer stem cell-like properties by altered regulation of cell cycle checkpoint and DNA repair network signaling
Published in PloS one (12-09-2014)“…Aldehyde dehydrogenase (ALDH) expressing cells have been characterized as possessing stem cell-like properties. We evaluated ALDH+ ovarian cancer stem…”
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Corrigendum to “Hedgehog/GLI1 Transcriptionally Regulates FANCD2 in Ovarian Tumor Cells: Its Inhibition Induces HR-Deficiency and Synergistic Lethality with PARP Inhibition.” [Neoplasia Volume 23, Issue 9, September 2021, Pages 1002-1015]
Published in Neoplasia (New York, N.Y.) (01-04-2024)Get full text
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Validation of a venous thromboembolism risk assessment model in gynecologic oncology
Published in Gynecologic oncology (01-07-2014)“…Abstract Objectives Gynecologic oncology patients undergoing surgery are at an increased risk for venous thromboembolism (VTE). We attempted to validate a VTE…”
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Second-line dovitinib (TKI258) in patients with FGFR2 -mutated or FGFR2 -non-mutated advanced or metastatic endometrial cancer: a non-randomised, open-label, two-group, two-stage, phase 2 study
Published in The lancet oncology (01-06-2015)“…Summary Background Activating FGFR2 mutations are found in 10–16% of primary endometrial cancers and provide an opportunity for targeted therapy. We assessed…”
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Hedgehog/GLI1 Transcriptionally Regulates FANCD2 in Ovarian Tumor Cells: Its Inhibition Induces HR-Deficiency and Synergistic Lethality with PARP Inhibition
Published in Neoplasia (New York, N.Y.) (01-09-2021)“…Ovarian cancer (OC) is one of the most lethal type of cancer in women due to a lack of effective targeted therapies and high rates of treatment resistance and…”
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A prospective blinded evaluation of the accuracy of frozen section for the surgical management of endometrial cancer
Published in Obstetrics and gynecology (New York. 1953) (01-12-2006)“…To prospectively evaluate in a blinded fashion the accuracy of frozen section in endometrial cancer. Sixty patients with endometrial cancer or complex atypical…”
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Long-term follow-up of Phase 2A trial results involving advanced ovarian cancer patients treated with Vigil® in frontline maintenance
Published in Gynecologic oncology reports (01-11-2020)Get full text
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Racial health disparities in ovarian cancer: not just black and white
Published in Journal of ovarian research (21-09-2017)“…Ovarian cancer (OC) is the most lethal gynecological malignancy, which disproportionately affects African American (AA) women. Lack of awareness and…”
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Long-Term Follow-Up of Gemogenovatucel-T (Vigil) Survival and Molecular Signals of Immune Response in Recurrent Ovarian Cancer
Published in Vaccines (Basel) (12-08-2021)“…Aim: To determine the relationship between gene expression profile (GEP) and overall survival (OS) by NanoString following treatment with Vigil. Patients and…”
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Society of Gynecologic Oncology Journal Club: Controversial conversations in gynecologic cancer – Navigating maintenance therapy for homologous recombinant proficient ovarian cancer
Published in Gynecologic oncology reports (01-12-2022)“…The Society of Gynecologic Oncology (SGO) Journal Club is an open forum to review pertinent studies relevant to controversial topics in the management of…”
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ENTPD1/CD39 as a predictive marker of treatment response to gemogenovatucel-T as maintenance therapy in newly diagnosed ovarian cancer
Published in Communications medicine (29-08-2022)“…Background Broadened use of predictive molecular and phenotypic profiling amongst oncologists has facilitated optimal integration of targeted- and…”
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A comparison of cisplatin/paclitaxel and carboplatin/paclitaxel in stage IVB, recurrent or persistent cervical cancer
Published in Gynecologic oncology (01-05-2007)“…Abstract Objective. Cisplatin-based combination therapy produces higher response rates and improved survival, in comparison to single-agent cisplatin in the…”
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MicroRNAs in gynecological cancers: Small molecules with big implications
Published in Cancer letters (28-10-2017)“…Abstract Gynecological cancers (GCs) are often diagnosed at advanced stages, limiting the efficacy of available therapeutic options. Thus, there remains an…”
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Immune checkpoint expression, microsatellite instability, and mutational burden: Identifying immune biomarker phenotypes in uterine cancer
Published in Gynecologic oncology (01-02-2020)“…Increasing grade of endometrioid endometrial cancer (EEC) is associated with aggressive behavior and poor prognosis. The traditional classification system is…”
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Gemogenovatucel-T (Vigil) immunotherapy as maintenance in frontline stage III/IV ovarian cancer (VITAL): a randomised, double-blind, placebo-controlled, phase 2b trial
Published in The lancet oncology (01-12-2020)“…Gemogenovatucel-T is an autologous tumour cell vaccine manufactured from harvested tumour tissue, which specifically reduces expression of furin and downstream…”
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Impact of Travel Time on Health Care Costs and Resource Use by Phase of Care for Older Patients With Cancer
Published in Journal of clinical oncology (01-08-2019)“…Many community cancer clinics closed between 2008 and 2016, with additional closings potentially expected. Limited data exist on the impact of travel time on…”
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CD44+/CD24− ovarian cancer cells demonstrate cancer stem cell properties and correlate to survival
Published in Clinical & experimental metastasis (01-12-2012)“…Cancer cells with the surface marker profile CD44+/CD24− have previously been described to possess cancer stem cell-like properties. This manuscript evaluates…”
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