Search Results - "Rocco, Patrícia Rieken Macêdo"
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Lung Injury Is Induced by Abrupt Increase in Respiratory Rate but Prevented by Recruitment Maneuver in Mild Acute Respiratory Distress Syndrome in Rats
Published in Anesthesiology (Philadelphia) (01-04-2023)“…Gradually changing respiratory rate (RR) during time to reduce ventilation-induced lung injury has not been investigated. The authors hypothesized that…”
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2
Current understanding of the immunosuppressive properties of mesenchymal stromal cells
Published in Journal of molecular medicine (Berlin, Germany) (01-05-2019)“…Several studies have demonstrated the anti-inflammatory potential of mesenchymal stromal cells (MSCs) isolated from bone marrow, adipose tissue, placenta, and…”
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Mechanisms of ventilator-induced lung injury in healthy lungs
Published in Best practice & research. Clinical anaesthesiology (01-09-2015)“…Mechanical ventilation is an essential method of patient support, but it may induce lung damage, leading to ventilator-induced lung injury (VILI). VILI is the…”
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The potential of mesenchymal stem cell therapy for chronic lung disease
Published in Expert review of respiratory medicine (02-01-2020)“…: Mesenchymal stem/stromal cells (MSCs) have been shown to improve lung function and survival in chronic inflammatory lung diseases, including asthma, chronic…”
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5
Anti-inflammatory properties of anesthetic agents
Published in Critical care (London, England) (21-03-2017)“…This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online…”
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6
Possible mechanisms of Pseudomonas aeruginosa -associated lung disease
Published in International journal of medical microbiology (01-01-2016)“…Abstract Pseudomonas aeruginosa is an opportunistic bacterium causing lung injury in immunocompromised patients correlated with high morbidity and mortality…”
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7
Distinct phenotypes require distinct respiratory management strategies in severe COVID-19
Published in Respiratory physiology & neurobiology (01-08-2020)“…•Chest CT patterns in COVID-19 may be divided into three main phenotypes with different characteristics o In phenotype 1, respiratory mechanics are consistent…”
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Close down the lungs and keep them resting to minimize ventilator-induced lung injury
Published in Critical care (London, England) (20-03-2018)“…This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2018. Other selected articles can be found online…”
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Current understanding of the therapeutic benefits of mesenchymal stem cells in acute respiratory distress syndrome
Published in Cell biology and toxicology (01-02-2020)“…The acute respiratory distress syndrome (ARDS) is a multifaceted lung disorder in which no specific therapeutic intervention is able to effectively improve…”
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Pathogenesis of Multiple Organ Injury in COVID-19 and Potential Therapeutic Strategies
Published in Frontiers in physiology (28-01-2021)“…Severe acute respiratory disease coronavirus 2 (SARS-CoV-2, formerly 2019-nCoV) is a novel coronavirus that has rapidly disseminated worldwide, causing the…”
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Immunomodulation after ischemic stroke: potential mechanisms and implications for therapy
Published in Critical care (London, England) (07-12-2016)“…Brain injuries are often associated with intensive care admissions, and carry high morbidity and mortality rates. Ischemic stroke is one of the most frequent…”
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Effects of a novel roflumilast and formoterol fumarate dry powder inhaler formulation in experimental allergic asthma
Published in International journal of pharmaceutics (15-10-2020)“…In this study we aimed to develop a roflumilast (R) and formoterol fumarate (F) dry powder inhaler formulation (DPI) incorporating HPβCD by spray drying and…”
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Mitochondria in Focus: From Function to Therapeutic Strategies in Chronic Lung Diseases
Published in Frontiers in immunology (23-11-2021)“…Mitochondria are essential organelles for cell metabolism, growth, and function. Mitochondria in lung cells have important roles in regulating surfactant…”
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14
Human adipose tissue mesenchymal stromal cells and their extracellular vesicles act differentially on lung mechanics and inflammation in experimental allergic asthma
Published in Stem cell research & therapy (24-06-2017)“…Asthma is a chronic inflammatory disease that can be difficult to treat due to its complex pathophysiology. Most current drugs focus on controlling the…”
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Dasatinib Reduces Lung Inflammation and Fibrosis in Acute Experimental Silicosis
Published in PloS one (20-01-2016)“…Silicosis is an occupational lung disease with no effective treatment. We hypothesized that dasatinib, a tyrosine kinase inhibitor, might exhibit therapeutic…”
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Neurological Complications and Noninvasive Multimodal Neuromonitoring in Critically Ill Mechanically Ventilated COVID-19 Patients
Published in Frontiers in neurology (27-11-2020)“…The incidence and the clinical presentation of neurological manifestations of coronavirus disease-2019 (COVID-19) remain unclear. No data regarding the use of…”
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New perspectives in nanotherapeutics for chronic respiratory diseases
Published in Biophysical reviews (01-10-2017)“…According to the World Health Organization (WHO), hundreds of millions of people of all ages and in all countries suffer from chronic respiratory diseases,…”
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In situ evidence of collagen V and signaling pathway of found inflammatory zone 1 (FIZZ1) is associated with silicotic granuloma in lung mice
Published in Pathology, research and practice (01-09-2020)“…Inhalation of silica particles causes silicosis: an occupational lung disease characterized by persistent inflammation with granuloma formation that leads to…”
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Clinical features, electroencephalogram, and biomarkers in pediatric sepsis-associated encephalopathy
Published in Scientific reports (23-06-2022)“…To date, no specific diagnostic criteria for sepsis-associated encephalopathy (SAE) have been established. We studied 33 pediatric patients with sepsis…”
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Pharmacological Agents and Potential New Therapies in Pulmonary Arterial Hypertension
Published in Current vascular pharmacology (01-01-2024)“…Pulmonary arterial hypertension (PAH) is a progressive disease characterized by an imbalance between vasoactive mediators, which causes vascular remodeling,…”
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