Search Results - "Rocco, Patrícia R.M."

Systemic Administration of Human Bone Marrow‐Derived Mesenchymal Stromal Cell Extracellular Vesicles Ameliorates Aspergillus Hyphal Extract‐Induced Allergic Airway Inflammation in Immunocompetent Mice by Cruz, Fernanda F., Borg, Zachary D., Goodwin, Meagan, Sokocevic, Dino, Wagner, Darcy E., Coffey, Amy, Antunes, Mariana, Robinson, Kristen L., Mitsialis, S. Alex, Kourembanas, Stella, Thane, Kristen, Hoffman, Andrew M., McKenna, David H., Rocco, Patricia R.M., Weiss, Daniel J.

“…The effect of systemic administration of conditioned media (CM) and extracellular vesicles (EVs) from both human and mouse bone marrow‐derived mesenchymal…”
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Freshly Thawed and Continuously Cultured Human Bone Marrow‐Derived Mesenchymal Stromal Cells Comparably Ameliorate Allergic Airways Inflammation in Immunocompetent Mice by Cruz, Fernanda F., Borg, Zachary D., Goodwin, Meagan, Sokocevic, Dino, Wagner, Darcy, McKenna, David H., Rocco, Patricia R.M., Weiss, Daniel J.

“…This study addressed whether freshly thawed mesenchymal stromal cells (MSCs) are as effective in in vivo settings as those that have been continuously…”
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Serum from Asthmatic Mice Potentiates the Therapeutic Effects of Mesenchymal Stromal Cells in Experimental Allergic Asthma by Abreu, Soraia C., Xisto, Debora G., Oliveira, Tainá B., Blanco, Natalia G., Castro, Lígia Lins, Kitoko, Jamil Zola, Olsen, Priscilla C., Lopes‐Pacheco, Miquéias, Morales, Marcelo M., Weiss, Daniel J., Rocco, Patricia R.M.

“…Asthma is a chronic inflammatory disease characterized by airway inflammation and remodeling, which can lead to progressive decline of lung function. Although…”
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Current status of cell-based therapies for respiratory virus infections: applicability to COVID-19 by Khoury, Maroun, Cuenca, Jimena, Cruz, Fernanda F, Figueroa, Fernando E, Rocco, Patricia R M, Weiss, Daniel J

“…The severe respiratory consequences of the coronavirus disease 2019 (COVID-19) pandemic have prompted urgent need for novel therapies. Cell-based approaches,…”
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Protective effects of bone marrow mononuclear cell therapy on lung and heart in an elastase-induced emphysema model by Cruz, Fernanda F, Antunes, Mariana A, Abreu, Soraia C, Fujisaki, Lívia C, Silva, Johnatas D, Xisto, Débora G, Maron-Gutierrez, Tatiana, Ornellas, Debora S, Sá, Vanessa K, Rocha, Nazareth N, Capelozzi, Vera L, Morales, Marcelo M, Rocco, Patricia R.M

“…Highlights ► Bone marrow cells had a protective effect on lung and heart in emphysema. ► Bone marrow cells modulated inflammation and remodeling in emphysema…”
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Early and late effects of bone marrow-derived mononuclear cell therapy on lung and distal organs in experimental sepsis by Ornellas, Debora S, Maron-Gutierrez, Tatiana, Ornellas, Felipe M, Cruz, Fernanda F, Oliveira, Gisele P, Lucas, Isabela H, Fujisaki, Livia, Oliveira, Mariana G, Teodoro, Walcy R, Capelozzi, Vera L, Pelosi, Paolo, Morales, Marcelo M, Rocco, Patricia R.M

“…Abstract We tested the hypothesis that bone marrow-derived mononuclear cells (BMDMCs) at an early phase of cecal ligation and puncture (CLP)-induced sepsis may…”
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Effects of bone marrow-derived mononuclear cells on airway and lung parenchyma remodeling in a murine model of chronic allergic inflammation by Abreu, Soraia C, Antunes, Mariana A, Maron-Gutierrez, Tatiana, Cruz, Fernanda F, Carmo, Luana G.R.R, Ornellas, Debora S, Junior, Humberto Carreira, Ab́Saber, Alexandre M, Parra, Edwin R, Capelozzi, Vera L, Morales, Marcelo M, Rocco, Patricia R.M

“…Abstract We hypothesized that bone marrow-derived mononuclear cells (BMDMC) would attenuate the remodeling process in a chronic allergic inflammation model…”
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Understanding the mechanisms of glutamine action in critically ill patients by Oliveira, Gisele P.(Universidade Federal do Rio de Janeiro Instituto de Biofísica Centro de Ciências da Saúde), Dias, Cristina M.(Universidade Federal do Rio de Janeiro Instituto de Biofísica Centro de Ciências da Saúde), Pelosi, Paolo(University of Insubria Department of Ambient, Health and Safety), Rocco, Patricia R.M.(Universidade Federal do Rio de Janeiro Instituto de Biofísica Centro de Ciências da Saúde)

“…Glutamine (Gln) is an important energy source and has been used as a supplementary energy substrate. Furthermore, Gln is an essential component for numerous…”
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Impact of obesity on airway and lung parenchyma remodeling in experimental chronic allergic asthma by Saraiva, Simone A, Silva, Adriana L, Xisto, Débora G, Abreu, Soraia C, Silva, Johnatas D, Silva, Pedro L, Teixeira, Tatiana P.F, Parra, Edwin R, Carvalho, Ana Laura N, Annoni, Raquel, Mauad, Thais, Capelozzi, Vera L, Silva, Patricia M.R, Martins, Marco A, Rocco, Patricia R.M

“…Abstract The impact of obesity on the inflammatory process has been described in asthma, however little is known about the influence of diet-induced obesity on…”
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Estimating the Damaging Power of High-Stress Ventilation by Marini, John J, Gattinoni, Luciano, Rocco, Patricia Rm

“…Redirection of our clinical attention from the pressures and volumes of the individual cycle to the broader and more inclusive considerations of energy load…”
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Elastase-Induced Lung Emphysema Models in Mice by Suki, Béla, Bartolák-Suki, Erzsébet, Rocco, Patricia R M

“…Pulmonary emphysema is one of the distinct pathological forms of chronic obstructive pulmonary disease (COPD) that is accompanied by gradual elimination of…”
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Protective function of DJ-1/PARK7 in lipopolysaccharide and ventilator-induced acute lung injury by Amatullah, Hajera, Maron-Gutierrez, Tatiana, Shan, Yuexin, Gupta, Sahil, Tsoporis, James N., Varkouhi, Amir K., Teixeira Monteiro, Ana Paula, He, Xiaolin, Yin, Jun, Marshall, John C., Rocco, Patricia R.M., Zhang, Haibo, Kuebler, Wolfgang M., dos Santos, Claudia C.

“…Oxidative stress is considered one of the early underlying contributors of acute lung injury (ALI) and ventilator-induced lung injury (VILI). DJ-1, also known…”
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Multiple doses of adipose tissue‐derived mesenchymal stromal cells induce immunosuppression in experimental asthma by Castro, Ligia L., Kitoko, Jamil Z., Xisto, Debora G., Olsen, Priscilla C., Guedes, Herbert L. M., Morales, Marcelo M., Lopes‐Pacheco, Miquéias, Cruz, Fernanda F., Rocco, Patricia R. M.

“…In experimental house dust mite (HDM)‐induced allergic asthma, therapeutic administration of a single dose of adipose tissue‐derived mesenchymal stromal cells…”
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Bone Marrow, Adipose, and Lung Tissue‐Derived Murine Mesenchymal Stromal Cells Release Different Mediators and Differentially Affect Airway and Lung Parenchyma in Experimental Asthma by Abreu, Soraia C., Antunes, Mariana A., Xisto, Debora G., Cruz, Fernanda F., Branco, Vivian C., Bandeira, Elga, Zola Kitoko, Jamil, de Araújo, Almair F., Dellatorre‐Texeira, Ludmilla, Olsen, Priscilla C., Weiss, Daniel J., Diaz, Bruno L., Morales, Marcelo M., Rocco, Patricia R. M.

“…Mesenchymal stromal cells (MSCs) from different sources have differential effects on lung injury. To compare the effects of murine MSCs from bone marrow (BM),…”
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Mesenchymal Stromal Cells Are More Effective Than Their Extracellular Vesicles at Reducing Lung Injury Regardless of Acute Respiratory Distress Syndrome Etiology by Lopes-Pacheco, Miquéias, Cruz, Fernanda F., Rocco, Patricia R. M., dos Santos, Claudia C., Morales, Marcelo M., Barbosa-Junior, Carlos M., Trivelin, Stefano A., De Oliveira, Gisele P., Braga, Cassia L., de Castro, Ligia L., Silva, Johnatas D., Weiss, Daniel J.

“…Although mesenchymal stromal cells (MSCs) have demonstrated beneficial effects on experimental acute respiratory distress syndrome (ARDS), preconditioning may…”
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Comparative effects of neurally adjusted ventilatory assist and variable pressure support on lung and diaphragmatic function in a model of acute respiratory distress syndrome: A randomised animal study by Scharffenberg, Martin, Moraes, Lillian, Güldner, Andreas, Huhle, Robert, Braune, Anja, Zeidler-Rentzsch, Ines, Kasper, Michael, Kunert-Keil, Christiane, Koch, Thea, Pelosi, Paolo, Rocco, Patricia R.M., Gama de Abreu, Marcelo, Kiss, Thomas

“…BACKGROUNDVariable assisted mechanical ventilation has been shown to improve lung function and reduce lung injury. However, differences between extrinsic and…”
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Mesenchymal Stem Cell Therapy for Acute Respiratory Distress Syndrome: A Light at the End of the Tunnel? by Lee, Jae-Woo, Rocco, Patricia R.M, Pelosi, Paolo

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Elastase-induced pulmonary emphysema: insights from experimental models by Antunes, Mariana A, Rocco, Patricia R M

“…Several distinct stimuli can be used to reproduce histological and functional features of human emphysema, a leading cause of disability and death. Since…”
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Ten golden rules for individualized mechanical ventilation in acute respiratory distress syndrome by Battaglini, Denise, Sottano, Marco, Ball, Lorenzo, Robba, Chiara, Rocco, Patricia R.M., Pelosi, Paolo

“…Considerable progress has been made over the last decades in the management of acute respiratory distress syndrome (ARDS). Mechanical ventilation(MV) remains…”
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Mesenchymal stromal cell therapy in COPD: from bench to bedside by Antunes, Mariana A, Lapa E Silva, José Roberto, Rocco, Patricia Rm

“…COPD is the most frequent chronic respiratory disease and a leading cause of morbidity and mortality. The major risk factor for COPD development is cigarette…”
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