Search Results - "Rocchi, Serena"
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Second Revision of the International Staging System (R2-ISS) for Overall Survival in Multiple Myeloma: A European Myeloma Network (EMN) Report Within the HARMONY Project
Published in Journal of clinical oncology (10-10-2022)“…Patients with newly diagnosed multiple myeloma (NDMM) show heterogeneous outcomes, and approximately 60% of them are at intermediate-risk according to the…”
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PET/CT Improves the Definition of Complete Response and Allows to Detect Otherwise Unidentifiable Skeletal Progression in Multiple Myeloma
Published in Clinical cancer research (01-10-2015)“…To evaluate the role of 18F-FDG PET/CT in 282 symptomatic multiple myeloma patients treated up-front between 2002 and 2012. All patients were studied by PET/CT…”
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Safety and efficacy of daratumumab in dialysis-dependent renal failure secondary to multiple myeloma
Published in Haematologica (Roma) (01-06-2018)Get full text
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Multiple Myeloma: The Role of Autologous Stem Cell Transplantation in the Era of Immunotherapy
Published in Cells (Basel, Switzerland) (16-05-2024)“…Upfront high-dose therapy with melphalan (HDM) followed by autologous stem cell transplantation (ASCT) has established itself as a core treatment for newly…”
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Novel insights and therapeutic approaches in secondary AML
Published in Frontiers in oncology (29-07-2024)“…Secondary acute myeloid leukemia (sAML) presents as a complex and multifaceted ensemble of disorders, positioning itself as both a challenge and an intriguing…”
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What is the best treatment strategy before autologous peripheral blood stem cell transplantation in POEMS syndrome?
Published in Haematologica (Roma) (01-03-2024)“…Autologous peripheral blood stem cell transplantation (aPBSCT) provides optimal outcomes in POEMS syndrome but the definition of the best treatment before…”
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Monoclonal gammopathy of renal significance (MGRS): Real‐world data on outcomes and prognostic factors
Published in American journal of hematology (01-07-2022)“…Monoclonal gammopathy of renal significance (MGRS) is a recognized clinical entity. Literature regarding treatment and its outcomes in MGRS is sparse due to…”
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Identification of a Maturation Plasma Cell Index through a Highly Sensitive Droplet Digital PCR Assay Gene Expression Signature Validation in Newly Diagnosed Multiple Myeloma Patients
Published in International journal of molecular sciences (18-10-2022)“…DNA microarrays and RNA-based sequencing approaches are considered important discovery tools in clinical medicine. However, cross-platform reproducibility…”
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Safety of Rapid Daratumumab Infusion: A Retrospective, Multicenter, Real-Life Analysis on 134 Patients With Multiple Myeloma
Published in Frontiers in oncology (14-03-2022)“…The anti-CD38 monoclonal antibody daratumumab is the backbone of most anti-multiple myeloma (MM) regimens. To mitigate the risk of infusion-related reactions…”
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Severe SARS-CoV-2 and subsequent fungal infections after CAR T-cell therapy for relapsed/refractory multiple myeloma: a challenging and happy ending fight
Published in Leukemia research reports (2024)“…Chimeric antigen receptor (CAR) T-cells have unveiled a promising therapeutic horizon for relapsed/refractory multiple myeloma (R/R MM). Nevertheless, immune…”
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Maintenance therapy with bortezomib and dexamethasone after autotransplantation for high-risk multiple myeloma
Published in Bone marrow transplantation (Basingstoke) (01-09-2020)Get full text
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High levels of CRBN isoform lacking IMiDs binding domain predicts for a worse response to IMiDs-based upfront therapy in newly diagnosed myeloma patients
Published in Clinical and experimental medicine (01-12-2023)“…In recent years, the immunoderivative (IMiD) agents have been extensively used for the treatment of multiple myeloma (MM). IMiDs and their newer derivatives…”
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Long term follow-up of humoral and cellular response to mRNA-based vaccines for SARS-CoV-2 in patients with active multiple myeloma
Published in Frontiers in oncology (25-05-2023)“…Long-term kinetics of antibody (Ab) and cell-mediated immune (CMI) response to full anti-SARS-CoV-2 vaccine schedule and booster doses in Multiple Myeloma (MM)…”
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A New Risk Stratification Model (R2-ISS) in Newly Diagnosed Multiple Myeloma: Analysis of Mature Data from 7077 Patients Collected By European Myeloma Network within Harmony Big Data Platform
Published in Blood (05-11-2020)“…Background. The Revised International Staging system (R-ISS) is the standard risk stratification model used for newly diagnosed (ND) multiple myeloma (MM)…”
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The ALLgorithMM: How to define the hemodilution of bone marrow samples in lymphoproliferative diseases
Published in Frontiers in oncology (06-10-2022)“…Introduction Minimal residual disease (MRD) is commonly assessed in bone marrow (BM) aspirate. However, sample quality can impair the MRD measurement, leading…”
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Interference of daratumumab and efficacy of plerixafor on haematopoietic stem cell collection in Multiple Myeloma
Published in Frontiers in hematology (26-04-2024)“…The impact of daratumumab on CD34+ hematopoietic stem cell (HSC) mobilization has recently been a matter of concern. To address this issue, we compared CD34+…”
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Single-Cell DNA Sequencing Reveals an Evolutionary Pattern of CHIP in Transplant Eligible Multiple Myeloma Patients
Published in Cells (Basel, Switzerland) (09-04-2024)“…Clonal hematopoiesis of indeterminate potential (CHIP) refers to the phenomenon where a hematopoietic stem cell acquires fitness-increasing mutation(s),…”
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Peripheral neuropathy induced by subcutaneous bortezomib-based induction therapy for newly diagnosed multiple myeloma
Published in Haematologica (Roma) (01-11-2014)Get full text
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