Search Results - "Rocchetti, Maria Teresa"
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1
Urine Proteome Analysis May Allow Noninvasive Differential Diagnosis of Diabetic Nephropathy
Published in Diabetes care (01-11-2010)“…OBJECTIVE: Chronic renal insufficiency and/or proteinuria in type 2 diabetes may stem from chronic renal diseases (CKD) other than classic diabetic nephropathy…”
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2
The Pathogenic Role of PI3K/AKT Pathway in Cancer Onset and Drug Resistance: An Updated Review
Published in Cancers (05-08-2021)“…The PI3K/AKT pathway is one of the most frequently over-activated intracellular pathways in several human cancers. This pathway, acting on different downstream…”
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3
Microbiota metabolites: Pivotal players of cardiovascular damage in chronic kidney disease
Published in Pharmacological research (01-04-2018)“…[Display omitted] In chronic kidney disease (CKD), cardiovascular (CV) damage is present in parallel which leads to an increased risk of CV disease. Both…”
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New Strategies for the Reduction of Uremic Toxins: How Much More We Know
Published in Toxins (24-11-2021)“…The importance of uremic toxin (UTx) removal in chronic kidney disease (CKD) is an emerging topic in the literature, widely recognized over time as a strategy…”
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5
Apigenin: Molecular Mechanisms and Therapeutic Potential against Cancer Spreading
Published in International journal of molecular sciences (20-05-2024)“…Due to its propensity to metastasize, cancer remains one of the leading causes of death worldwide. Thanks in part to their intrinsic low cytotoxicity, the…”
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Bioprospecting Antimicrobials from Lactiplantibacillus plantarum : Key Factors Underlying Its Probiotic Action
Published in International journal of molecular sciences (08-11-2021)“…( ) is a well-studied and versatile species of lactobacilli. It is found in several niches, including human mucosal surfaces, and it is largely employed in the…”
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7
Altered urinary excretion of aquaporin 2 in IgA nephropathy
Published in European journal of endocrinology (01-10-2011)“…ObjectiveThe intrarenal renin–angiotensin system (RAS) activation plays a pivotal role in immunoglobulin A nephropathy (IgAN) pathogenesis, which is still…”
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8
Multi-Faceted Role of Luteolin in Cancer Metastasis: EMT, Angiogenesis, ECM Degradation and Apoptosis
Published in International journal of molecular sciences (16-05-2023)“…Luteolin (3',4',5,7-tetrahydroxyflavone), a member of the flavonoid family derived from plants and fruits, shows a wide range of biomedical applications. In…”
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9
Microbiota issue in CKD: how promising are gut-targeted approaches?
Published in Journal of nephrology (01-02-2019)“…In chronic kidney disease (CKD), the progressive decline in the renal excretory function leads to accumulation of urea and toxins in the blood. The…”
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10
Beta-Glucans Supplementation Associates with Reduction in P-Cresyl Sulfate Levels and Improved Endothelial Vascular Reactivity in Healthy Individuals
Published in PloS one (20-01-2017)“…Oat and barley beta-glucans are prebiotic fibers known for their cholesterol-lowering activity, but their action on the human gut microbiota metabolism is…”
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11
Nutritional Therapy Modulates Intestinal Microbiota and Reduces Serum Levels of Total and Free Indoxyl Sulfate and P-Cresyl Sulfate in Chronic Kidney Disease (Medika Study)
Published in Journal of clinical medicine (10-09-2019)“…In chronic kidney disease (CKD), the gut-microbiota metabolites indoxyl sulfate (IS) and p-cresyl sulfate (PCS) progressively accumulate due to their high…”
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12
Psychobiotic Properties of Lactiplantibacillus plantarum in Neurodegenerative Diseases
Published in International journal of molecular sciences (31-08-2024)“…Neurodegenerative disorders are the main cause of cognitive and physical disabilities, affect millions of people worldwide, and their incidence is on the rise…”
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13
An Innovative Synbiotic Formulation Decreases Free Serum Indoxyl Sulfate, Small Intestine Permeability and Ameliorates Gastrointestinal Symptoms in a Randomized Pilot Trial in Stage IIIb-IV CKD Patients
Published in Toxins (05-05-2021)“…Proteolytic dysbiosis of the gut microbiota has been recognized as both a typical feature of chronic kidney disease (CKD) and a risk factor for its…”
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14
Efficacy of Divinylbenzenic Resin in Removing Indoxyl Sulfate and P-Cresol Sulfate in Hemodialysis Patients: Results From an In Vitro Study and An In Vivo Pilot Trial (xuanro4-Nature 3.2)
Published in Toxins (10-03-2020)“…High serum levels of microbiota-derived uremic toxins, indoxyl sulfate (IS) and p-cresyl sulfate (PCS), are associated with chronic kidney disease (CKD)…”
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15
The Ambivalent Role of miRNAs in Carcinogenesis: Involvement in Renal Cell Carcinoma and Their Clinical Applications
Published in Pharmaceuticals (Basel, Switzerland) (02-04-2021)“…The analysis of microRNA (miRNAs), small, non-coding endogenous RNA, plays a crucial role in oncology. These short regulatory sequences, acting on thousands of…”
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Improving the In Vitro Removal of Indoxyl Sulfate and p-Cresyl Sulfate by Coating Diatomaceous Earth (DE) and Poly-vinyl-pyrrolidone-co-styrene (PVP-co-S) with Polydopamine
Published in Toxins (08-12-2022)“…Polydopamine (PDA) is a synthetic eumelanin polymer mimicking the biopolymer secreted by mussels to attach to surfaces with a high binding strength. It…”
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17
A neural network for glomerulus classification based on histological images of kidney biopsy
Published in BMC medical informatics and decision making (01-11-2021)“…Abstract Background Computer-aided diagnosis (CAD) systems based on medical images could support physicians in the decision-making process. During the last…”
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Lactiplantibacillus plantarum from Unexplored Tunisian Ecological Niches: Antimicrobial Potential, Probiotic and Food Applications
Published in Microorganisms (Basel) (01-11-2023)“…The continued exploration of the diversity of lactic acid bacteria in little-studied ecological niches represents a fundamental activity to understand the…”
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19
Metabolic Fingerprinting of Fabry Disease: Diagnostic and Prognostic Aspects
Published in Metabolites (28-07-2022)“…Fabry disease (FD) is an X-linked lysosomal disease due to a deficiency in the activity of the lysosomal-galactosidase A (GalA), a key enzyme in the…”
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Altered Phosphorylation of Cytoskeleton Proteins in Peripheral Blood Mononuclear Cells Characterizes Chronic Antibody-Mediated Rejection in Kidney Transplantation
Published in International journal of molecular sciences (05-09-2020)“…Chronic antibody-mediated rejection (CAMR) is the major cause of kidney transplant failure. The molecular mechanisms underlying this event are still poorly…”
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