Search Results - "Rocca, B"
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1
Aspirin, 110 years later
Published in Journal of thrombosis and haemostasis (01-07-2009)“…Although conceived at the end of the 19th century as a synthetic analgesic agent with improved gastric tolerability vs. naturally occurring salicylates,…”
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2
The interplay between indoleamine 2,3-dioxygenase 1 (IDO1) and cyclooxygenase (COX)-2 in chronic inflammation and cancer
Published in Current medicinal chemistry (01-05-2011)“…The enzyme indoleamine 2,3-dioxygenase 1 (IDO1) degrades the essential amino acid tryptophan into kynurenine and other downstream metabolites that suppress…”
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3
In Silico Modeling of the Antiplatelet Pharmacodynamics of Low‐dose Aspirin in Health and Disease
Published in Clinical pharmacology and therapeutics (01-11-2017)“…The influence of platelet turnover on cyclooxygenase (COX‐1) inhibition by low‐dose aspirin remains largely uncharacterized due to limited feasibility of…”
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The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low‐dose aspirin in patients with and without diabetes
Published in Journal of thrombosis and haemostasis (01-07-2012)“…See also Lordkipanidze M, Harrison P. Aspirin twice a day keeps new COX‐1 at bay. This issue, pp 1217–9. Summary Background. Interindividual variability in…”
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5
Group-based task-oriented exercises aimed at managing kinesiophobia improved disability in chronic low back pain
Published in European journal of pain (01-04-2016)“…Background There are still doubts concerning the clinical impact of multidisciplinary cognitive behavioural rehabilitation programmes conducted in group‐based…”
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On‐pump Cardiac Surgery Enhances Platelet Renewal and Impairs Aspirin Pharmacodynamics: Effects of Improved Dosing Regimens
Published in Clinical pharmacology and therapeutics (01-11-2017)“…On‐pump cardiac surgery may trigger inflammation and accelerate platelet cyclooxygenase‐1 renewal, thereby modifying low‐dose aspirin pharmacodynamics…”
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Qualitative and quantitative modifications of von Willebrand factor in patients with essential thrombocythemia and controlled platelet count
Published in Journal of thrombosis and haemostasis (01-07-2015)“…Summary Background Essential thrombocythemia (ET) is characterized by increased platelets and prevalent thrombosis. An acquired von Willebrand factor (VWF)…”
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8
Determinants of the interindividual variability in response to antiplatelet drugs
Published in Journal of thrombosis and haemostasis (01-08-2005)“…The aim of this review article is to discuss the main determinants of the interindividual variability in response to antiplatelet agents. The main sources of…”
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The impact of COVID-19 pandemic on the healthcare workers mental health
Published in European psychiatry (01-03-2023)“…Introduction The COVID-19 pandemic represents an unprecedented in health events that has had a negative impact on the mental health of the population in…”
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Platelet indices and glucose control in type 1 and type 2 diabetes mellitus: A case-control study
Published in Nutrition, metabolism, and cardiovascular diseases (01-10-2017)“…The relationship between platelet indices and glucose control may differ in type 1 (T1DM) and type 2 (T2DM) diabetes. We aimed to investigate differences in…”
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Longitudinal trajectories of psychosocial functioning in patients with pre-existing mental disorders after one year of COVID-19 pandemic
Published in Journal of psychiatric research (01-04-2024)“…Aims of the present study were to prospectively assess psychosocial functioning trajectories during the COVID pandemic and the possible impact of…”
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12
Development of the Italian version of the knee injury and osteoarthritis outcome score for patients with knee injuries: cross-cultural adaptation, dimensionality, reliability, and validity
Published in Osteoarthritis and cartilage (01-04-2012)“…Summary Objective Translating, culturally adapting and validating an Italian version of the Knee injury and Osteoarthritis Outcome Score (KOOS-I) to allow its…”
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13
Metformin improves endothelial function in type 1 diabetic subjects: a pilot, placebo-controlled randomized study
Published in Diabetes, obesity & metabolism (01-05-2013)“…Aims Several studies have investigated the effects of metformin treatment in patients with type 1 diabetes mellitus (T1DM). No study has hitherto examined its…”
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14
Starburst and old stellar populations in the z 3.8 radio galaxies 4C 41.17 and TN J2007−1316
Published in Monthly notices of the Royal Astronomical Society (11-03-2013)“…Using the new evolutionary code Pégase.3, we undertook an evolutionary spectral synthesis of the optical-IR-submm spectral energy distribution of two distant…”
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An in silico model of aspirin-iduced inactivation of platelet and Megakaryocyte Cyclooxygenase-1
Published in Clinical therapeutics (01-08-2015)“…[...]the model explains an increased COX-1 acetylation following a shorter dosing interval (100 mg twice daily) as compared to a higher (200 mg) once-daily…”
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16
An in silico model of aspirin-iduced inactivation of platelet and Megakaryocyte Cyclooxygenase-1
Published in Clinical therapeutics (01-08-2015)“…[...]the model explains an increased COX-1 acetylation following a shorter dosing interval (100 mg twice daily) as compared to a higher (200 mg) once-daily…”
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Incidence and prognostic significance of karyotype abnormalities in de novo primary myelodysplastic syndromes : a study on 331 patients from a single institution
Published in Leukemia (01-08-2005)“…The impact of clinical parameters, International Prognostic Scoring System (IPSS) scores/cytogenetic categories, and some single cytogenetic defects on overall…”
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Cystic gastrointestinal stromal tumors of the pancreas simulating cystoadenocarcinoma. Report of three cases and short review of the literature
Published in Histology and histopathology (01-12-2014)“…Gastrointestinal stromal tumors (GISTs) represent a distinct subset of mesenchymal tumours of the gastrointestinal tract. They are more common in the stomach…”
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Structural dynamics of the mitochondrial ADP/ATP carrier revealed by molecular dynamics simulation studies
Published in Proteins, structure, function, and bioinformatics (15-11-2006)“…The mitochondrial adenosine diphosphate/adenosine triphosphate (ADP/ATP) carrier has been recently crystallized in complex with its specific inhibitor…”
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Myeloid sarcoma and adenocarcinoma of the large bowel as collision tumors: a case report
Published in Histology and histopathology (01-07-2012)“…Myeloid sarcoma is a rare tumor composed of myeloid cells, localized in an extramedullary site, which may be associated with a concurrent myeloid neoplasm…”
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