Search Results - "Roca, Lise"

A pooled analysis of the cardiac events in the trastuzumab adjuvant trials by de Azambuja, Evandro, Ponde, Noam, Procter, Marion, Rastogi, Priya, Cecchini, Reena S., Lambertini, Matteo, Ballman, Karla, Aspitia, Alvaro Moreno, Zardavas, Dimitrios, Roca, Lise, Gelber, Richard D., Piccart-Gebhart, Martine, Suter, Thomas

“…Background Trastuzumab-associated cardiotoxicity remains an issue for patients with HER2-positive breast cancer. This pooled analysis of 3 adjuvant trials…”
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Changes in vitamin D and calcium metabolism markers in patients undergoing adjuvant chemotherapy for breast cancer by Viala, Marie, Firmin, Nelly, Touraine, Célia, Pouderoux, Stéphane, Metge, Manon, Rifai, Lobna, Romieu, Gilles, de Forges, Hélène, Roca, Lise, Guiu, Séverine, D'Hondt, Véronique, Jacot, William

“…Changes in calcium metabolism and calcium urinary excretion during chemotherapy have not been thoroughly assessed in patients with early breast cancer (EBC), a…”
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A Phase II Multicenter Trial on High-Dose Vitamin D Supplementation for the Correction of Vitamin D Insufficiency in Patients with Breast Cancer Receiving Adjuvant Chemotherapy by Chartron, Elodie, Firmin, Nelly, Touraine, Célia, Chapelle, Angélique, Legouffe, Eric, Rifai, Lobna, Pouderoux, Stéphane, Roca, Lise, D'Hondt, Véronique, Jacot, William

“…Breast cancer (BC) treatments induce vitamin D (VD) insufficiency and bone metabolism changes, resulting in osteoporosis and skeletal morbidity risk. We report…”
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The 21-gene Recurrence Score® assay predicts distant recurrence in lymph node-positive, hormone receptor-positive, breast cancer patients treated with adjuvant sequential epirubicin- and docetaxel-based or epirubicin-based chemotherapy (PACS-01 trial) by Penault-Llorca, Frédérique, Filleron, Thomas, Asselain, Bernard, Baehner, Frederick L, Fumoleau, Pierre, Lacroix-Triki, Magali, Anderson, Joseph M, Yoshizawa, Carl, Cherbavaz, Diana B, Shak, Steven, Roca, Lise, Sagan, Christine, Lemonnier, Jérôme, Martin, Anne-Laure, Roché, Henri

“…The 21-gene Recurrence Score (RS) result predicts outcome and chemotherapy benefit in node-negative and node-positive (N+), estrogen receptor-positive (ER+)…”
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Characterization of an adaptive immune response in microsatellite-instable colorectal cancer by Boissière-Michot, Florence, Lazennec, Gwendal, Frugier, Hélène, Jarlier, Marta, Roca, Lise, Duffour, Jacqueline, Du Paty, Emilie, Laune, Daniel, Blanchard, France, Le Pessot, Florence, Sabourin, Jean-Christophe, Bibeau, Frédéric

“…Sporadic or hereditary colorectal cancer (CRC) with microsatellite instability (MSI) is frequently characterized by inflammatory lymphocytic infiltration and…”
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A UNICANCER phase III trial of hyperthermic intra-peritoneal chemotherapy (HIPEC) for colorectal peritoneal carcinomatosis (PC): PRODIGE 7 by Quenet, François, Elias, Dominique, Roca, Lise, Goere, Diane, Ghouti, Laurent, Pocard, Marc, Facy, Olivier, Arvieux, Catherine, Lorimier, Gerard, Pezet, Denis, Marchal, Frederic, Loi, Valeria, Meeus, Pierre, De Forges, Hélène, Stanbury, Trevor, Paineau, Jacques, Glehen, Olivier

“…Abstract only LBA3503 Background: Promising results have been obtained during the last decade using cytoreductive surgery (CRS) plus HIPEC for selected…”
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Etoposide, mitomycin, and methotrexate combination in heavily treated breast cancer: a retrospective study by Aldabbagh, Kais, Pouderoux, Stéphane, Roca, Lise, Poujol, Sylvain, Fabbro, Michel, Romieu, Gilles, Jacot, William

“…Background Since 2004, metastatic breast cancer patients pretreated with anthracyclines, taxanes, and capecitabine have been treated in our institution with a…”
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Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open-label, phase 3 trial by Quénet, François, Elias, Dominique, Roca, Lise, Goéré, Diane, Ghouti, Laurent, Pocard, Marc, Facy, Olivier, Arvieux, Catherine, Lorimier, Gérard, Pezet, Denis, Marchal, Frédéric, Loi, Valeria, Meeus, Pierre, Juzyna, Beata, de Forges, Hélène, Paineau, Jacques, Glehen, Olivier, MARIANI, Pascale, BRIGAND, Cécile, BEREDER, Jean-Marc, MSIKA, Simon, PORTIER, Guillaume, RAT, Patrick

“…The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to cytoreductive surgery has been associated with encouraging survival results in some…”
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Limitations of the PRODIGE 7 trial – Authors' reply by Quénet, François, Roca, Lise, de Forges, Hélène, Gléhen, Olivier, Goéré, Diane

“…For this reason, we continue to believe that the use of systemic chemotherapy in general could be one explanation for the substantial difference in the overall…”
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Results of Two Bi-Institutional Prospective Studies Using Intraperitoneal Oxaliplatin With or Without Irinotecan During HIPEC After Cytoreductive Surgery for Colorectal Carcinomatosis by QUENET, François, GOERE, Diane, SHARAD MEHTA, Sanket, ROCA, Lise, DUMONT, Fréderic, HESSISSEN, Mehdi, SAINT-AUBERT, Bernard, ELIAS, Dominique

“…To assess the perioperative and long-term results of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) using…”
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Long-term results of dose escalation (80 vs 70 Gy) combined with long-term androgen deprivation in high-risk prostate cancers: GETUG-AFU 18 randomized trial by Hennequin, Christophe, Sargos, Paul, Roca, Lise, Silva, Marlon, Latorzeff, Igor, Peiffert, Didier, Cozzi, Salvatore, Benyoucef, Ahmed, Hasbini, Ali, Supiot, Stephane, Ronchin, Philippe, Wachter, Thierry, Azria, David, Cailleux, Pierre-Etienne, Cormier, Luc, Zibouche, Mallik, Pigné, Grégoire

“…LBA259 Background: Radiotherapy (RT) delivered in combination with androgen deprivation therapy (ADT) improve survival for patients with prostate…”
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Pattern and risk factors of isolated local relapse among women with hormone receptor-positive and HER2-negative breast cancer and lymph node involvement: 10-year follow-up analysis of the PACS 01 and PACS 04 trials by Rassy, Elie, Filleron, Thomas, Viansone, Alessandro, Lacroix-Triki, Magali, Rivera, Sofia, Desmoulins, Isabelle, Serin, Daniel, Canon, Jean Luc, Campone, Mario, Gonçalves, Anthony, Levy, Christelle, Cottu, Paul, Petit, Thierry, Eymard, Jean-Christophe, Debled, Marc, Bachelot, Thomas, Dalenc, Florence, Roca, Lise, Lemonnier, Jerôme, Delaloge, Suzette, Pistilli, Barbara

“…Purpose We aimed to determine the pattern of isolated local recurrences (ILR) in women with stage II-III hormone receptor-positive and human epidermal growth…”
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Abstract OT-13-05: Dolaf- an international multicenter phase 2 trial of durvalumab (medi4736) plus olaparib plus fulvestrant in metastatic or locally advanced er-positive, her2-negative breast cancer patients selected using criteria that predict sensitivity to olaparib (UCBG308) by Guiu, Severine, Balmana, Judith, Roca, Lise, Goncalves, Anthony, Mailliez, Audrey, Bigot, Frederic, Bachelot, Thomas, Dalenc, Florence, Dohollou, Nadine, Genet, Dominique, Desmoulins, Isabelle, Chakiba, Camille, Delaloge, Suzette, Martineau, Geraldine, Haddad, Veronique, Follana, Philippe

“…Abstract Background: Olaparib is a PARP inhibitor that has shown high response rates and clinical activity in patients with advanced HER2-negative breast…”
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Exploring the Efficacy of Pembrolizumab in Combination with Carboplatin and Weekly Paclitaxel for Frail Patients with Advanced Non-Small-Cell Lung Cancer: A Key Investigative Study by Thomas, Quentin Dominique, Chaabouni, Mohamed, Al Herk, Anas, Lefevbre, Cesar, Cavaillon, Sarah, Sinoquet, Léa, Pouderoux, Stéphane, Viala, Marie, Roca, Lise, Quantin, Xavier

“…Immune checkpoint blockers have revolutionized the first-line treatment of advanced non-small-cell lung cancer (NSCLC). Pembrolizumab, an anti-PD-1 monoclonal…”
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UCBG 2-04: Long-term results of the PACS 04 trial evaluating adjuvant epirubicin plus docetaxel in node-positive breast cancer and trastuzumab in the human epidermal growth factor receptor 2–positive subgroup by D'Hondt, Véronique, Canon, Jean-Luc, Roca, Lise, Levy, Christelle, Pierga, Jean-Yves, Le Du, Fanny, Campone, Mario, Desmoulins, Isabelle, Goncalves, Anthony, Debled, Marc, Rios, Maria, Ferrero, Jean-Marc, Serin, Daniel, Hardy-Bessard, Anne-Claire, Piot, Gilles, Brain, Etienne, Dohollou, Nadine, Orfeuvre, Hubert, Lemonnier, Jerome, Roché, Henri, Delaloge, Suzette, Dalenc, Florence

“…We conducted a double-randomised phase III trial to evaluate a concomitant taxane-anthracycline regimen in node-positive breast cancer and the efficacy of…”
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Five year letrozole versus placebo in BRCA1/2 germline mutations carriers: Final results of LIBER, a double-blind randomized phase III breast cancer prevention trial by Pujol, Pascal, Roca, Lise, Lortholary, Alain, Lasset, Christine, Dugast, Catherine, Berthet, Pascaline, Tennevet, Isabelle, Fricker, Jean-Pierre, Nathalie, Chabbert-Buffet, Gesta, Paul, This, Pascale, Chiesa, Jean, N'Guyen, TD, Mailliez, Audrey, Venat-Bouvet, Laurence, Dreyfus, Hélène, Delnatte, Capucine, Galibert, Virginie, Lemonnier, Jerome, Delaloge, Suzette

“…Abstract only 1534 Background: Women with germline BRCA1/2 (gBRCA1/2) mutations have a 70% lifetime risk of breast cancer (BC). Medical prevention by aromatase…”
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Tumour biology, metastatic sites and taxanes sensitivity as determinants of eribulin mesylate efficacy in breast cancer: results from the ERIBEX retrospective, international, multicenter study by Dell'Ova, Mélodie, De Maio, Eléonora, Guiu, Séverine, Roca, Lise, Dalenc, Florence, Durigova, Anna, Pinguet, Frédéric, Bekhtari, Khedidja, Jacot, William, Pouderoux, Stéphane

“…Our retrospective, international study aimed at evaluating the activity and safety of eribulin mesylate (EM) in pretreated metastatic breast cancer (MBC) in a…”
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Two-stage hepatectomy for colorectal liver metastases: Pathologic response to preoperative chemotherapy is associated with second-stage completion and longer survival by Quénet, François, Pissas, Marie-Hélène, Gil, Hugo, Roca, Lise, Carrère, Sébastien, Sgarbura, Olivia, Rouanet, Philippe, de Forges, Hélène, Khellaf, Lakhdar, Deshayes, Emmanuel, Ychou, Marc, Bibeau, Frédéric

“…Two-stage hepatectomy of bilobar colorectal liver metastases is widely used and shows encouraging survival results. However, the risk of dropout after the…”
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Correlation of HER2, FCGR2A, and FCGR3A gene polymorphisms with trastuzumab related cardiac toxicity and efficacy in a subgroup of patients from UNICANCER-PACS04 trial by Roca, Lise, Diéras, Véronique, Roché, Henri, Lappartient, Emmanuelle, Kerbrat, Pierre, Cany, Laurent, Chieze, Stéphanie, Canon, Jean-Luc, Spielmann, Marc, Penault-Llorca, Frédérique, Martin, Anne-Laure, Mesleard, Christel, Lemonnier, Jérôme, de Cremoux, Patricia

“…The purpose of this study was to investigate, in the context of a prospective node-positive-breast cancer trial HER2 containing-regimen (UNICANCER-PACS 04…”
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UCBG 2-08: 5-year efficacy results from the UNICANCER-PACS08 randomised phase III trial of adjuvant treatment with FEC100 and then either docetaxel or ixabepilone in patients with early-stage, poor prognosis breast cancer by Campone, Mario, Lacroix-Triki, Magali, Roca, Lise, Spielmann, Marc, Wildiers, Hans, Cottu, Paul, Kerbrat, Pierre, Levy, Christelle, Desmoulins, Isabelle, Bachelot, Thomas, Winston, Tan, Eymard, Jean-Christophe, Uwer, Lionel, Duhoux, Francois P., Verhoeven, Didier, Jaubert, Dominique, Coeffic, David, Orfeuvre, Hubert, Canon, Jean Luc, Asselain, Bernard, Martin, Anne-Laure, Lemonnier, Jerome, Roché, Henri

“…UNICANCER-PACS08 compared adjuvant FEC (5-FU; epirubicin; cyclophosphamide) then docetaxel to FEC then ixabepilone in poor prognosis early breast cancer (BC)…”
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