Search Results - "Robustelli Della Cuna, Gioacchino"
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Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6
Published in Blood (01-07-2002)“…We studied concentration, phenotype, and function of peripheral blood (PB) dendritic cells (DCs) from patients with multiple myeloma (MM). The absolute number…”
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Molecular and Functional Bases of Self-Antigen Recognition in Long-Term Persistent Melanocyte-Specific CD8+ T Cells in One Vitiligo Patient
Published in Journal of investigative dermatology (01-08-2003)“…Vitiligo patients possess high frequencies of circulating CD8+ T lymphocytes specific for the melanocyte differentiation antigen Melan-A/MART-1. These…”
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Effects of the Medicago scutellata Trypsin Inhibitor (MsTI) on Cisplatin-induced Cytotoxicity in Human Breast and Cervical Cancer Cells
Published in Anticancer research (01-01-2004)“…Background: Snail medic (Medicago scutellata L.) seeds exhibit a significantly higher content of a trypsin inhibitor than other Medicago species. This…”
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T‐cell dynamics after high‐dose chemotherapy in adults: elucidation of the elusive CD8+ subset reveals multiple homeostatic T‐cell compartments with distinct implications for immune competence
Published in Immunology (01-05-2002)“…Summary Recovery of total T cell numbers after in vivo T‐cell depletion in humans is accompanied by complex perturbation within the CD8+ subset. We aimed to…”
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Allogeneic blood stem cell transplantation after a reduced-intensity, preparative regimen: A pilot study in patients with refractory malignancies
Published in Cancer (01-05-2002)“…The immune-mediated graft-versus-tumor (GVT) effect plays a therapeutic role in the treatment of patients with hematologic malignancies who undergo allogeneic…”
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Megakaryocytic progenitors can be generated ex vivo and safely administered to autologous peripheral blood progenitor cell transplant recipients
Published in Blood (15-04-1997)“…We evaluated different culture conditions to obtain a lineage-selected proliferation of clonogenic megakaryocytic progenitors (MP). In low-density (LD) or…”
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Dominant TCR-alpha requirements for a self antigen recognition in humans
Published in The Journal of immunology (1950) (01-12-2002)“…TCR-alpha and -beta chains are composed of somatically rearranged V, D, and J germline-encoded gene segments that confer Ag specificity. Recent…”
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Prospective phase II study of single-agent gemcitabine in untreated elderly patients with stage IIIB/IV non-small-cell lung cancer
Published in American journal of clinical oncology (01-12-2001)“…The purpose of this study was to evaluate the efficacy and tolerability of single-agent gemcitabine in untreated elderly patients with stage IIIb/IV…”
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Evaluation of infectious complications and immune recovery following high-dose chemotherapy (HDC) and autologous peripheral blood progenitor cell transplantation (PBPC-T) in 148 breast cancer patients
Published in Anticancer research (01-11-2002)“…High-dose chemotherapy (HDC) with autologous PBPC-T has been reported to be effective in hematological and in selected solid malignancies. In this setting,…”
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Multilineage long-term engraftment potential of drug-resistant hematopoietic progenitors
Published in Blood (15-10-1997)“…Peripheral blood progenitor cells (PBPCs) are increasingly used instead of bone marrow for autologous or allogeneic transplantation. In this study PBPCs…”
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Coexistence of Two Functioning T-Cell Repertoires in Healthy Ex-Thalassemics Bearing a Persistent Mixed Chimerism Years After Bone Marrow Transplantation
Published in Blood (15-11-1999)“…Bone marrow transplantation (BMT) from an HLA-identical donor is an established therapy to cure homozygous β-thalassemia. Approximately 10% of thalassemic…”
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Allogeneic blood stem cell transplantation after a reduced‐intensity, preparative regimen
Published in Cancer (01-05-2002)“…BACKGROUND The immune‐mediated graft‐versus‐tumor (GVT) effect plays a therapeutic role in the treatment of patients with hematologic malignancies who undergo…”
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13
Natural interferon‐alpha activity in hormone‐sensitive, hormone‐resistant and autonomous human breast‐cancer cell lines
Published in International journal of cancer (11-06-1997)“…This study explored the activity of natural interferon‐alpha (nIFN‐α) in regulating cell growth of 6 breast‐cancer cell lines. The anti‐proliferative effect of…”
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Negative immunomagnetic purging of peripheral blood stem cell harvests from breast carcinoma patients reduces tumor cell contamination while not affecting hematopoietic recovery
Published in Cancer (15-06-2000)“…BACKGROUND Because tumor contamination of hematopoietic stem cell grafts may influence the outcome in breast carcinoma (BC) patients undergoing high dose…”
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Characteristics and biological role of steroid hormone receptors in neuroepithelial tumors
Published in Journal of neurosurgery (01-11-1990)“…Tissue samples from 57 patients with neuroepithelial tumors (25 glioblastomas, 18 anaplastic astrocytomas, and 14 astrocytomas) were analyzed in order to…”
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A study on the biological behavior of human brain tumors. Part II: Steroid receptors and arachidonic acid metabolism
Published in Journal of neuro-oncology (01-06-1991)“…The significance of steroid receptors (SR) in human brain tumors is presently a field of intense investigation in order to clarify some aspects of the…”
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Circulating CD33+ large mononuclear cells contain three distinct populations with phenotype of putative antigen‐presenting cells including myeloid dendritic cells and CD14+ monocytes with their CD16+ subset
Published in Cytometry (New York, N.Y.) (01-10-2001)“…Background In peripheral blood, myeloid markers identify a heterogeneous mixture of cells in transit from the bone marrow to peripheral tissues. Similarly,…”
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Diverse expansion potential and heterogeneous avidity in tumor‐associated antigen‐specific T lymphocytes from primary melanoma patients
Published in European journal of immunology (01-02-2001)“…While tumor‐associated antigen (TAA)‐specific CD8+ T lymphocytes have been detected in metastatic melanoma patients, immune response in early disease phases…”
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Dominant TCR-{alpha} Requirements for a Self Antigen Recognition in Humans
Published in The Journal of immunology (1950) (01-12-2002)“…TCR-[alpha] and -[beta] chains are composed of somatically rearranged V, D, and J germline-encoded gene segments that confer Ag specificity. Recent…”
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