Search Results - "Robson, Stephen C"
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Use of MRI in the diagnosis of fetal brain abnormalities in utero (MERIDIAN): a multicentre, prospective cohort study
Published in The Lancet (British edition) (04-02-2017)“…Summary Background In-utero MRI (iuMRI) has shown promise as an adjunct to ultrasound but the comparative diagnostic performance has been poorly defined. We…”
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Vaginal progesterone prophylaxis for preterm birth (the OPPTIMUM study): a multicentre, randomised, double-blind trial
Published in The Lancet (British edition) (21-05-2016)“…Summary Background Progesterone administration has been shown to reduce the risk of preterm birth and neonatal morbidity in women at high risk, but there is…”
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Universal third-trimester ultrasonic screening using fetal macrosomia in the prediction of adverse perinatal outcome: A systematic review and meta-analysis of diagnostic test accuracy
Published in PLoS medicine (13-10-2020)“…The effectiveness of screening for macrosomia is not well established. One of the critical elements of an effective screening program is the diagnostic…”
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Effect of a behavioural intervention in obese pregnant women (the UPBEAT study): a multicentre, randomised controlled trial
Published in The lancet. Diabetes & endocrinology (01-10-2015)“…Summary Background Behavioural interventions might improve clinical outcomes in pregnant women who are obese. We aimed to investigate whether a complex…”
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Prevalence, Natural History, and Clinical Outcome of Mild to Moderate Ventriculomegaly
Published in Obstetrics and gynecology (New York. 1953) (01-04-2011)“…To estimate the prevalence, associated anomalies, progression, and clinical outcome in fetuses diagnosed with mild to moderate ventriculomegaly at 18-24 weeks…”
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Formalin-Fixed Paraffin-Embedded (FFPE) samples are not a beneficial replacement for frozen tissues in fetal membrane microbiota research
Published in PloS one (17-03-2022)“…Formalin-Fixed Paraffin-Embedded (FFPE) tissues are routinely collected, archived, and used for clinical diagnosis, including maternal and neonatal health…”
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MRI in the diagnosis of fetal developmental brain abnormalities: the MERIDIAN diagnostic accuracy study
Published in Health technology assessment (Winchester, England) (01-09-2019)“…Ultrasonography has been the mainstay of antenatal screening programmes in the UK for many years. Technical factors and physical limitations may result in…”
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Expression of angiogenic growth factors by uterine natural killer cells during early pregnancy
Published in Journal of leukocyte biology (01-09-2006)“…Remodeling of uterine spiral arteries is critical for the continuation of a successful pregnancy. Uterine natural killer (uNK) cells are the predominant…”
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Evaluation of the Arabin cervical pessary for prevention of preterm birth in women with a twin pregnancy and short cervix (STOPPIT-2): An open-label randomised trial and updated meta-analysis
Published in PLoS medicine (29-03-2021)“…Preterm-labour-associated preterm birth is a common cause of perinatal mortality and morbidity in twin pregnancy. We aimed to test the hypothesis that the…”
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Epidemiology, Natural History, Progression, and Postnatal Outcome of Severe Fetal Ventriculomegaly
Published in Obstetrics and gynecology (New York. 1953) (01-12-2012)“…To estimate the prevalence, associated anomalies, progression, and clinical outcome in fetuses prenatally diagnosed with severe ventriculomegaly. This is a…”
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The role of vascular smooth muscle cell apoptosis and migration during uterine spiral artery remodeling in normal human pregnancy
Published in The FASEB journal (01-07-2012)“…ABSTRACT During human uterine spiral artery (SpA) remodeling, vascular smooth muscle cells (VSMCs) are lost and replaced by fibrinoid, incorporating…”
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Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis
Published in Canadian Medical Association journal (CMAJ) (11-03-2008)“…Alterations in waveforms in the uterine artery are associated with the development of pre-eclampsia and intrauterine growth restriction. We investigated the…”
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Treatments for hyperemesis gravidarum and nausea and vomiting in pregnancy: a systematic review and economic assessment
Published in Health technology assessment (Winchester, England) (01-10-2016)“…Nausea and vomiting in pregnancy (NVP) affects up to 85% of all women during pregnancy, but for the majority self-management suffices. For the remainder,…”
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Universal late pregnancy ultrasound screening to predict adverse outcomes in nulliparous women: a systematic review and cost-effectiveness analysis
Published in Health technology assessment (Winchester, England) (01-02-2021)“…Currently, pregnant women are screened using ultrasound to perform gestational aging, typically at around 12 weeks' gestation, and around the middle of…”
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Physical activity in pregnancy: a qualitative study of the beliefs of overweight and obese pregnant women
Published in BMC pregnancy and childbirth (28-04-2010)“…Whilst there has been increasing research interest in interventions which promote physical activity during pregnancy few studies have yielded detailed insights…”
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Altered decidual leucocyte populations in the placental bed in pre-eclampsia and foetal growth restriction: a comparison with late normal pregnancy
Published in Reproduction (Cambridge, England) (01-07-2009)“…Alterations in the balance of leucocyte populations in uterine decidua may lead to the generation of an unfavourable cytokine environment that is associated…”
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The Arabin pessary to prevent preterm birth in women with a twin pregnancy and a short cervix: the STOPPIT 2 RCT
Published in Health technology assessment (Winchester, England) (01-07-2021)“…Preterm birth is common in twins and accounts for significant mortality and morbidity. There are no effective preventative treatments. Some studies have…”
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Guidelines for the management of spontaneous preterm labor: identification of spontaneous preterm labor, diagnosis of preterm premature rupture of membranes, and preventive tools for preterm birth
Published in The journal of maternal-fetal & neonatal medicine (01-05-2011)Get full text
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Does progesterone prophylaxis to prevent preterm labour improve outcome? A randomised double-blind placebo-controlled trial (OPPTIMUM)
Published in Health technology assessment (Winchester, England) (01-06-2018)“…Progesterone prophylaxis is widely used to prevent preterm birth but is not licensed and there is little information on long-term outcome. To determine the…”
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Acetylation of Heat Shock Protein 20 (Hsp20) Regulates Human Myometrial Activity
Published in The Journal of biological chemistry (30-09-2011)“…Phosphorylation of heat shock protein 20 (Hsp20) by protein kinase A (PKA) is now recognized as an important regulatory mechanism modulating contractile…”
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