Search Results - "Robson, Richard A."

The pharmacokinetics of oral fleroxacin and ciprofloxacin in plasma and sputum during acute and chronic dosing by Begg, Evan J., Robson, Richard A., Saunders, Darren A., Graham, Garry G., Buttimore, Rona C., Neill, Alister M., Town, G. Ian

“…Aims To examine the pharmacokinetics of ciprofloxacin and fleroxacin in plasma and sputum of patients with an acute exacerbation of chronic bronchitis or…”
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Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure by Mcgregor, David O., Dellow, Warwick J., Robson, Richard A., Lever, Michael, George, Peter M., Chambers, Stephen T.

“…Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure. Fasting and post-methionine load hyperhomocysteinemia are…”
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The effects of quinolones on xanthine pharmacokinetics by Robson, R A

“…Caffeine, theobromine, and theophylline are among the most widely consumed compounds in beverages and in pharmaceutical preparations. These methylxanthine…”
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Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations by Mcgregor, David O., Dellow, Warwick J., Lever, Michael, George, Peter M., Robson, Richard A., Chambers, Stephen T.

“…Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations. Hyperhomocysteinemia is a risk factor for atherosclerosis that…”
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Pharmacokinetics of Etoricoxib in Patients with Renal Impairment by Agrawal, Nancy G. B., Matthews, Catherine Z., Mazenko, Ralph S., Kline, Walter F., Woolf, Eric J., Porras, Arturo G., Geer, Leslie A., Wong, Peggy H., Cho, Meehung, Cote, Josee, Marbury, Thomas C., Moncrief, Jack W., Alcorn Jr, Harry, Swan, Suzanne, Sack, Marshall R., Robson, Richard A., Petty, Kevin J., Schwartz, Jules I., Gottesdiener, Keith M.

“…The effect of renal insufficiency on the pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase‐2, was examined in 23 patients with varying…”
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An Exploratory Trial of an Investigational RNA Therapeutic, IONIS-FB-LRx, for Treatment of IgA Nephropathy: SA-PO714 by Barbour, Sean, Hladunewich, Michelle A., Irvine, John, Makris, Angela, Robson, Richard A., Tan, Sven-Jean, Wong, Muh Geot, Frazer-Abel, Ashley, Yang, Qingqing, Yin, Lixuan, Barrett, Terry, Ruckle, Jon L., Schneider, Eugene, Geary, Richard, Canducci, Filippo, Mccaleb, Michael

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Glycine betaine excretion is not directly linked to plasma glucose concentrations in hyperglycaemia by Dellow, Warwick J., Chambers, Stephen T., Barrell, Graham K., Lever, Michael, Robson, Richard A.

“…Diabetes mellitus subjects, type 1 and type 2, have increased glycine betaine excretion compared to normal subjects that correlated with plasma glucose and HbA…”
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Abnormal glycine betaine content of the blood and urine of diabetic and renal patients by Lever, M, Sizeland, P C, Bason, L M, Hayman, C M, Robson, R A, Chambers, S T

“…In normal human plasma the concentrations of the renal osmolyte, glycine betaine, are usually between 20 and 70 mumol/l, in adult males (median 44 mumol/l)…”
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Haemolytic-uraemic syndrome in a renal transplant recipient treated by conversion to mycophenolate mofetil by McGregor, D O, Robson, R A, Lynn, K L

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Intravenous drug use and glomerular deposition of lipid-like material by Lynn, K L, Pickering, W, Gardner, J, Bailey, R R, Robson, R A

“…We present a series of 5 intravenous drug users (4 male, age range 24-47 years) with glomerular deposition of a lipid-like material. Three patients presented…”
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OKT3 for the treatment of steroid-resistant acute renal allograft rejection by Jogose, J T, Bailey, R R, Lynn, K L, Robson, R A, Wells, J E

“…OKT3 (Orthoclone) was first used in this unit on February 25, 1987. Up until March 31, 1996, 153 patients had a total of 163 transplants. Fifty of these…”
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Anemia and angiotensin-converting enzyme inhibition in renal transplant recipients by Sizeland, P C, Bailey, R R, Lynn, K L, Robson, R A

“…The renin-angiotensin system has been shown to have an effect on erythropoietin synthesis and hemoglobin concentration. We present a retrospective study of…”
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Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations by Mcgregor, David O., Dellow, Warwick J., Lever, Michael, George, Peter M., Robson, Richard A., Chambers, Stephen T.

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Comparison of automated percutaneous kidney biopsy using needles of different gauge by LYNN, Kelvin L, WONG, Kim M, WELSH, Geoffrey J, LAWLER, Lance, GARDNER, Jacqui, BAILEY, Ross R, ROBSON, Richard A, MALING, Tom MJ

“…Percutaneous renal biopsy, an essential procedure for the evaluation of a patient with renal disease, has been improved by the use of semi‐automated,…”
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Effect of hemodialysis and recombinant human erythropoietin on determinants of blood viscosity by Shand, B I, Buttimore, A L, Lynn, K L, Bailey, R R, Robson, R A

“…Blood viscosity (hemorheology) is a major determinant of the rate of blood flow, and increases in viscosity are known to be involved in the etiology of…”
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Elevated glycine betaine excretion in diabetes mellitus patients is associated with proximal tubular dysfunction and hyperglycemia by Dellow, Warwick J., Chambers, Stephen T., Lever, Michael, Lunt, Helen, Robson, Richard A.

“…In an ambulatory population of diabetic subjects (Type 1 and Type 2), the urine excretion of the renal osmolyte, glycine betaine, was compared to known markers…”
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Predicting renal survival in primary focal glomerulosclerosis from the time of presentation by Chitalia, Vipul C., Elisabeth Wells, J., Robson, Richard A., Searle, Martin, Lynn, Kelvin L.

“…Predicting renal survival in primary focal glomerulosclerosis from the time of presentatiom To Predict the risk of developing chronic renal failure in patients…”
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Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations by Miners, J O, Smith, K J, Robson, R A, McManus, M E, Veronese, M E, Birkett, D J

“…Tolbutamide hydroxylation has been investigated in human liver microsomes. Anti-human liver NADPH-cytochrome P-450 reductase IgG inhibited hydroxytolbutamide…”
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The role of mycophenolate mofetil in chickenpox after renal transplantation by Jose, M D, Roake, J A, Robson, R A

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Characterisation of theophylline metabolism by human liver microsomes. Inhibition and immunochemical studies by Robson, R A, Miners, J O, Matthews, A P, Stupans, I, Meller, D, McManus, M E, Birkett, D J

“…Anti-human NADPH-cytochrome P-450 reductase inhibited all theophylline metabolic pathways confirming the involvement of cytochrome P-450 isozymes in the…”
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