Search Results - "Robson, H."

Notch Signaling in the Immune System by Radtke, Freddy, Fasnacht, Nicolas, MacDonald, H. Robson

“…The Notch signaling pathway regulates many aspects of embryonic development, as well as differentiation processes and tissue homeostasis in multiple adult…”
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Regulation of innate and adaptive immunity by Notch by Radtke, Freddy, MacDonald, H. Robson, Tacchini-Cottier, Fabienne

“…Key Points Notch signalling has several important roles in driving both the development and function of cells of the immune system. During lymphocyte…”
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NLRC5 exclusively transactivates MHC class I and related genes through a distinctive SXY module by Ludigs, Kristina, Seguín-Estévez, Queralt, Lemeille, Sylvain, Ferrero, Isabel, Rota, Giorgia, Chelbi, Sonia, Mattmann, Chantal, MacDonald, H Robson, Reith, Walter, Guarda, Greta

“…MHC class II (MHCII) genes are transactivated by the NOD-like receptor (NLR) family member CIITA, which is recruited to SXY enhancers of MHCII promoters via a…”
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Neurogenic subventricular zone stem/progenitor cells are Notch1-dependent in their active but not quiescent state by Basak, Onur, Giachino, Claudio, Fiorini, Emma, Macdonald, H Robson, Taylor, Verdon

“…The adult mammalian forebrain contains neural stem/progenitor cells (NSCs) that generate neurons throughout life. As in other somatic stem cell systems, NSCs…”
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Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair by Wilson, Anne, Laurenti, Elisa, Oser, Gabriela, van der Wath, Richard C., Blanco-Bose, William, Jaworski, Maike, Offner, Sandra, Dunant, Cyrille F., Eshkind, Leonid, Bockamp, Ernesto, Lió, Pietro, MacDonald, H. Robson, Trumpp, Andreas

“…Bone marrow hematopoietic stem cells (HSCs) are crucial to maintain lifelong production of all blood cells. Although HSCs divide infrequently, it is thought…”
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Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses by Fasnacht, Nicolas, Huang, Hsin-Ying, Koch, Ute, Favre, Stéphanie, Auderset, Floriane, Chai, Qian, Onder, Lucas, Kallert, Sandra, Pinschewer, Daniel D, MacDonald, H Robson, Tacchini-Cottier, Fabienne, Ludewig, Burkhard, Luther, Sanjiv A, Radtke, Freddy

“…Fibroblast-like cells of secondary lymphoid organs (SLO) are important for tissue architecture. In addition, they regulate lymphocyte compartmentalization…”
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Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes by Jiang, Wei, Wang, Xiaqiong, Zeng, Benhua, Liu, Lei, Tardivel, Aubry, Wei, Hong, Han, Jiahuai, MacDonald, H Robson, Tschopp, Jurg, Tian, Zhigang, Zhou, Rongbin

“…NOD2 functions as an intracellular sensor for microbial pathogen and plays an important role in epithelial defense. The loss-of-function mutation of NOD2 is…”
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Enhancing tropical conservation and ecology research with aquatic environmental DNA methods: an introduction for non‐environmental DNA specialists by Huerlimann, R., Cooper, M. K., Edmunds, R. C., Villacorta‐Rath, C., Le Port, A., Robson, H. L. A., Strugnell, J. M., Burrows, D., Jerry, D. R.

“…Biodiversity conservation is a worldwide concern and proper management of threatened species or communities depends on reliable and accurate data collection…”
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Simultaneous loss of β- and γ-catenin does not perturb hematopoiesis or lymphopoiesis by Koch, Ute, Wilson, Anne, Cobas, Monica, Kemler, Rolf, MacDonald, H. Robson, Radtke, Freddy

“…Hematopietic stem cells (HSCs) maintain life-long hematopoiesis in the bone marrow via their ability to self-renew and to differentiate into all blood…”
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Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes by Preston, Gavin C, Sinclair, Linda V, Kaskar, Aneesa, Hukelmann, Jens L, Navarro, Maria N, Ferrero, Isabel, MacDonald, H Robson, Cowling, Victoria H, Cantrell, Doreen A

“…Myc controls the metabolic reprogramming that supports effector T cell differentiation. The expression of Myc is regulated by the T cell antigen receptor (TCR)…”
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Tri-metallic transition metal–nitrogen–carbon catalysts derived by sacrificial support method synthesis by Serov, Alexey, Robson, Michael H., Smolnik, Mayat, Atanassov, Plamen

“…A series of tri-metallic oxygen reduction catalysts derived from pyrolyzed Fe-M1-M2 (where M=Co, Ni, Cu and Mn) and 4-aminoantipyrine (Fe-M1-M2-AAPyr) were…”
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Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment by Koch, Ute, Fiorini, Emma, Benedito, Rui, Besseyrias, Valerie, Schuster-Gossler, Karin, Pierres, Michel, Manley, Nancy R, Duarte, Antonio, Macdonald, H Robson, Radtke, Freddy

“…Thymic T cell lineage commitment is dependent on Notch1 (N1) receptor-mediated signaling. Although the physiological ligands that interact with N1 expressed on…”
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Notch regulation of lymphocyte development and function by Radtke, Freddy, Wilson, Anne, Mancini, Stephane J C, MacDonald, H Robson

“…Notch proteins regulate a broad spectrum of cell fate decisions and differentiation processes during fetal and postnatal development. Mammals have four Notch…”
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Developing HSCs become Notch independent by the end of maturation in the AGM region by Souilhol, Céline, Lendinez, Javier G., Rybtsov, Stanislav, Murphy, Fiona, Wilson, Heather, Hills, David, Batsivari, Antoniana, Binagui-Casas, Anahí, McGarvey, Alison C., MacDonald, H.Robson, Kageyama, Ryoichiro, Siebel, Christian, Zhao, Suling, Medvinsky, Alexander

“…The first definitive hematopoietic stem cells (dHSCs) in the mouse emerge in the dorsal aorta of the embryonic day (E) 10.5 to 11 aorta-gonad-mesonephros (AGM)…”
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Templated bi-metallic non-PGM catalysts for oxygen reduction by Serov, Alexey, Robson, Michael H., Smolnik, Mayat, Atanassov, Plamen

“…A series of bi-metallic oxygen reduction catalysts derived from pyrolyzed Fe–M (where M=Co, Cu, Ni and Mn) and 4-aminoantipyrine (Fe–M–AAPyr) compounds were…”
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The Effect of Red & Blue Rich LEDs vs Fluorescent Light on Lollo Rosso Lettuce Morphology and Physiology by Cammarisano, Laura, Donnison, Iain S, Robson, Paul R H

“…The challenges of feeding an increasing population, an increasingly urban population and within an increasingly challenging global environment have focused…”
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Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity by Laurenti, Elisa, Varnum-Finney, Barbara, Wilson, Anne, Ferrero, Isabel, Blanco-Bose, William E, Ehninger, Armin, Knoepfler, Paul S, Cheng, Pei-Feng, MacDonald, H Robson, Eisenman, Robert N, Bernstein, Irwin D, Trumpp, Andreas

“…Myc activity is emerging as a key element in acquisition and maintenance of stem cell properties. We have previously shown that c-Myc deficiency results in…”
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Turbopump Parametric Modelling and Reliability Assessment for Reusable Rocket Engine Applications by Gulczyński, Mateusz T., Hahn, Robson H. S., Deeken, Jan C., Oschwald, Michael

“…The development of modern reusable launchers, such as the Themis project with its LOX/LCH4 Prometheus engine, CALLISTO—a reusable VTVL-launcher first-stage…”
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The impact of soil salinity on the yield, composition and physiology of the bioenergy grass Miscanthus × giganteus by Stavridou, Evangelia, Hastings, Astley, Webster, Richard J., Robson, Paul R. H.

“…High salinity land may provide an alternative resource for the cultivation of dedicated biomass crops for renewable energy and chemicals, thus avoiding…”
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Disrupting the EMMPRIN (CD147)–Cyclophilin A Interaction Reduces Infarct Size and Preserves Systolic Function After Myocardial Ischemia and Reperfusion by Seizer, Peter, Ochmann, Carmen, Schönberger, Tanja, Zach, Sebastian, Rose, Melanie, Borst, Oliver, Klingel, Karin, Kandolf, Reinhard, MacDonald, H Robson, Nowak, Romana A, Engelhardt, Stefan, Lang, Florian, Gawaz, Meinrad, May, Andreas E

“…OBJECTIVE—Inflammation and proteolysis crucially contribute to myocardial ischemia and reperfusion injury. The extracellular matrix metalloproteinase inducer…”
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