Search Results - "Robles, Eloy F."

C/EBPα Induces Highly Efficient Macrophage Transdifferentiation of B Lymphoma and Leukemia Cell Lines and Impairs Their Tumorigenicity by Rapino, Francesca, Robles, Eloy F., Richter-Larrea, Jose A., Kallin, Eric M., Martinez-Climent, Jose A., Graf, Thomas

“…Earlier work demonstrated that the transcription factor C/EBPα can convert immature and mature murine B lineage cells into functional macrophages. Testing >20…”
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Disparate response to microoxia and nitrogen oxides of the Bradyrhizobium japonicum napEDABC, nirK and norCBQD denitrification genes by Bueno, Emilio, Robles, Eloy F., Torres, María J., Krell, Tino, Bedmar, Eulogio J., Delgado, María J., Mesa, Socorro

“…Expression of the Bradyrhizobium japonicum napEDABC, nirK and norCBQD denitrification genes requires low oxygen (O2) tension and nitrate (NO3−), through a…”
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Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma by Richter-Larrea, Jose A., Robles, Eloy F., Fresquet, Vicente, Beltran, Elena, Rullan, Antonio J., Agirre, Xabier, Calasanz, Maria José, Panizo, Carlos, Richter, Jose A., Hernandez, Jesus M., Roman-Gomez, Jose, Prosper, Felipe, Martinez-Climent, Jose A.

“…In Burkitt lymphoma/leukemia (BL), achievement of complete remission with first-line chemotherapy remains a challenging issue, as most patients who respond…”
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Downregulation of FOXP1 is required during germinal center B-cell function by Sagardoy, Ainara, Martinez-Ferrandis, Jose I., Roa, Sergio, Bunting, Karen L., Aznar, María Angela, Elemento, Olivier, Shaknovich, Rita, Fontán, Lorena, Fresquet, Vicente, Perez-Roger, Ignacio, Robles, Eloy F., De Smedt, Linde, Sagaert, Xavier, Melnick, Ari, Martinez-Climent, Jose A.

“…B-cell maturation and germinal center (GC) formation are dependent on the interplay between BCL6 and other transcriptional regulators. FOXP1 is a transcription…”
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Targeting the anion exchanger 2 with specific peptides as a new therapeutic approach in B lymphoid neoplasms by Celay, Jon, Lozano, Teresa, Concepcion, Axel R, Beltrán, Elena, Rudilla, Francesc, García-Barchino, María José, Robles, Eloy F, Rabal, Obdulia, de Miguel, Irene, Panizo, Carlos, Casares, Noelia, Oyarzabal, Julen, Prieto, Jesús, Medina, Juan F, Lasarte, Juan José, Martínez-Climent, José Ángel

“…Regulatory T (Treg) cells can weaken antitumor immune responses, and inhibition of their function appears to be a promising therapeutic approach in cancer…”
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LITAF, a BCL6 target gene, regulates autophagy in mature B‐cell lymphomas by Bertolo, Cristina, Roa, Sergio, Sagardoy, Ainara, Mena‐Varas, Maria, Robles, Eloy F., Martinez‐Ferrandis, Jose I., Sagaert, Xavier, Tousseyn, Thomas, Orta, Alberto, Lossos, Izidore S., Amar, Salomon, Natkunam, Yasodha, Briones, Javier, Melnick, Ari, Malumbres, Raquel, Martinez‐Climent, Jose A.

“…Summary We have previously reported that LITAF is silenced by promoter hypermethylation in germinal centre‐derived B‐cell lymphomas, but beyond these data the…”
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C/EBPα Induces Highly Efficient Macrophage Transdifferentiation of B Lymphoma and Leukemia Cell Lines and Impairs Their Tumorigenicity by Rapino, Francesca, Robles, Eloy F., Richter-Larrea, Jose A., Kallin, Eric M., Martinez-Climent, Jose A., Graf, Thomas

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Divergence of Vascular Specification in Visceral Lymphoid Organs-Genetic Determinants and Differentiation Checkpoints by Kellermayer, Zoltán, Hayasaka, Haruko, Kajtár, Béla, Simon, Diána, Robles, Eloy F., Martinez-Climent, Jose A., Balogh, Péter

“…Despite their functional similarities, peripheral lymphoid tissues are remarkably different according to their developmental properties and structural…”
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LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome by Malumbres, Raquel, Fresquet, Vicente, Roman-Gomez, Jose, Bobadilla, Miriam, Robles, Eloy F, Altobelli, Giovanna G, Calasanz, M José, Smeland, Erlend B, Aznar, Maria Angela, Agirre, Xabier, Martin-Palanco, Vanesa, Prosper, Felipe, Lossos, Izidore S, Martinez-Climent, Jose A

“…LMO2 is highly expressed at the most immature stages of lymphopoiesis. In T-lymphocytes, aberrant LMO2 expression beyond those stages leads to T-cell acute…”
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DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features by Arribas, Alberto J., Rinaldi, Andrea, Mensah, Afua A., Kwee, Ivo, Cascione, Luciano, Robles, Eloy F., Martinez-Climent, Jose A., Oscier, David, Arcaini, Luca, Baldini, Luca, Marasca, Roberto, Thieblemont, Catherine, Briere, Josette, Forconi, Francesco, Zamò, Alberto, Bonifacio, Massimiliano, Mollejo, Manuela, Facchetti, Fabio, Dirnhofer, Stephan, Ponzoni, Maurilio, Bhagat, Govind, Piris, Miguel A., Gaidano, Gianluca, Zucca, Emanuele, Rossi, Davide, Bertoni, Francesco

“…Splenic marginal zone lymphoma is a rare lymphoma. Loss of 7q31 and somatic mutations affecting the NOTCH2 and KLF2 genes are the commonest genomic…”
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Richter transformation driven by Epstein–Barr virus reactivation during therapy‐related immunosuppression in chronic lymphocytic leukaemia by García‐Barchino, Maria J, Sarasquete, Maria E, Panizo, Carlos, Morscio, Julie, Martinez, Antonio, Alcoceba, Miguel, Fresquet, Vicente, Gonzalez‐Farre, Blanca, Paiva, Bruno, Young, Ken H, Robles, Eloy F, Roa, Sergio, Celay, Jon, Larrayoz, Marta, Rossi, Davide, Gaidano, Gianluca, Montes‐Moreno, Santiago, Piris, Miguel A, Balanzategui, Ana, Jimenez, Cristina, Rodriguez, Idoia, Calasanz, Maria J, Larrayoz, Maria J, Segura, Victor, Garcia‐Muñoz, Ricardo, Rabasa, Maria P, Yi, Shuhua, Li, Jianyong, Zhang, Mingzhi, Xu‐Monette, Zijun Y, Puig‐Moron, Noemi, Orfao, Alberto, Böttcher, Sebastian, Hernandez‐Rivas, Jesus M, Miguel, Jesus San, Prosper, Felipe, Tousseyn, Thomas, Sagaert, Xavier, Gonzalez, Marcos, Martinez‐Climent, Jose A

“…The increased risk of Richter transformation (RT) in patients with chronic lymphocytic leukaemia (CLL) due to Epstein–Barr virus (EBV) reactivation during…”
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High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma by Fresquet, Vicente, Robles, Eloy F., Parker, Anton, Martinez-Useros, Javier, Mena, Maria, Malumbres, Raquel, Agirre, Xabier, Catarino, Susana, Arteta, David, Osaba, Lourdes, Mollejo, Manuela, Hernandez-Rivas, Jesus M., Calasanz, Maria Jose, Daibata, Masanori, Dyer, Martin J.S., Prosper, Felipe, Vizcarra, Esperanza, Piris, Miguel-Ángel, Oscier, David, Martinez-Climent, Jose Angel

“…Summary Using high‐resolution genomic microarray analysis, a distinct genomic profile was defined in 114 samples from patients with splenic marginal zone…”
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LITAF , a BCL 6 target gene, regulates autophagy in mature B‐cell lymphomas by Bertolo, Cristina, Roa, Sergio, Sagardoy, Ainara, Mena‐Varas, Maria, Robles, Eloy F., Martinez‐Ferrandis, Jose I., Sagaert, Xavier, Tousseyn, Thomas, Orta, Alberto, Lossos, Izidore S., Amar, Salomon, Natkunam, Yasodha, Briones, Javier, Melnick, Ari, Malumbres, Raquel, Martinez‐Climent, Jose A.

“…Summary We have previously reported that LITAF is silenced by promoter hypermethylation in germinal centre‐derived B‐cell lymphomas, but beyond these data the…”
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LITAF, a BCL6 Target Gene, Regulates Autophagia in B Cells and Is Essential for T-Cell Dependent Humoral Responses by Bertolo, Cristina, Malumbres, Raquel, Sagardoy, Ainara, Robles, Eloy F, Martinez-Ferrandis, Jose I, Roa, Sergio, Lossos, Izidore S, Sagaert, Xavier, Melnick, Ari, Amar, Salomon, Martinez-Climent, Jose A

“…Abstract 1391 LITAF was discovered as a p53-induced transcript that promoted TNFa secretion in monocytes in response to LPS. We previously reported that LITAF…”
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High‐throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF 5 as a potential tumour suppressor in splenic marginal‐zone lymphoma by Fresquet, Vicente, Robles, Eloy F., Parker, Anton, Martinez‐Useros, Javier, Mena, Maria, Malumbres, Raquel, Agirre, Xabier, Catarino, Susana, Arteta, David, Osaba, Lourdes, Mollejo, Manuela, Hernandez‐Rivas, Jesus M., Calasanz, Maria Jose, Daibata, Masanori, Dyer, Martin J.S., Prosper, Felipe, Vizcarra, Esperanza, Piris, Miguel‐Ángel, Oscier, David, Martinez‐Climent, Jose Angel

“…Summary Using high‐resolution genomic microarray analysis, a distinct genomic profile was defined in 114 samples from patients with splenic marginal zone…”
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Homeobox NKX2-3 Is Over-Expressed in Human B-Cell Lymphomas and Drives Marginal Zone B-Cell Lymphomagenesis in Mice by Robles, Eloy F, Aldaz, Beatriz, Akasaka, Takashi, Pellizzeri, Laura Macri, Martinez-Anso, Eduardo, Aguirre, Xavier, Prosper, Felipe, Martin-Guerrero, Idoia, Segura, Victor, Calasanz, Maria José, Sanchez-Garcia, Isidro, Campos-Sanchez, Elena, Cobaleda, Cesar, Cresson, Charlotte, Broccardo, Cyril, Siebert, Reiner, Sagaert, Xabier, Dyer, Martin JS, Martinez-Climent, Jose A

“…Abstract 260 While the molecular study of the common immunoglobulin (IG) translocations, hallmarks of B-cell lymphomas, led to the discovery of seminal cancer…”
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LM02 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome by MALUMBRES, Raquel, FRESQUET, Vicente, MARTIN-PALANCO, Vanesa, PROSPER, Felipe, LOSSOS, Izidore S, MARTINEZ-CLIMENT, Jose A, ROMAN-GOMEZ, Jose, BOBADILLA, Miriam, ROBLES, Eloy F, ALTOBELLI, Giovanna G, CALASANZ, José, SMELAND, Erlend B, AZNAR, Maria Angela, AGIRRE, Xabier

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