Search Results - "Robledo, Sara María"
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Antileishmanial activity of synthetic analogs of the naturally occurring quinolone alkaloid N-methyl-8-methoxyflindersin
Published in PloS one (28-12-2020)“…Leishmaniasis is a neglected, parasitic tropical disease caused by an intracellular protozoan from the genus Leishmania. Quinoline alkaloids, secondary…”
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Successful treatment of cutaneous leishmaniasis with intralesional meglumine antimoniate: A case series
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2019)“…Cutaneous leishmaniasis (CL) is a high-morbidity, vector-borne disease endemic to Colombia. Unlike conventional systemic antileishmanial therapy, intralesional…”
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Phenotypic and Functional Profiles of Antigen-Specific CD4 + and CD8 + T Cells Associated With Infection Control in Patients With Cutaneous Leishmaniasis
Published in Frontiers in cellular and infection microbiology (19-11-2018)“…The host immunological response is a key factor determining the pathogenesis of cutaneous leishmaniasis. It is known that a Th1 cellular response is associated…”
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In vitro and in vivo antileishmanial activity of Artemisia annua L. leaf powder and its potential usefulness in the treatment of uncomplicated cutaneous leishmaniasis in humans
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2017)“…Cutaneous leishmaniasis (CL) is a tropical disease that affects millions of individuals worldwide. The current drugs for CL may be effective but have serious…”
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S-allylCysteine Ester/Caffeic Acid Amide Hybrids as Promising Antiprotozoal Candidates: Synthesis, Biological Evaluation and Molecular Modeling Studies
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2022)“…Abstract In order to overcome the challenges of discovering new antiprotozoal drugs, we synthesized a new class of hybrids based on S-allylCysteine…”
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Leishmania (Viannia) panamensis expresses a nuclease with molecular and biochemical features similar to the Endonuclease G of higher eukaryotes
Published in Colombia médica (Cali, Colombia) (2011)“…Objective: To characterize the molecular and biochemical features of the Endonuclease G of Leishmania (Viannia) panamensis. Methods: The gene of the putative…”
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Phylogenetic and evolutionary analysis of dengue virus serotypes circulating at the Colombian–Venezuelan border during 2015–2016 and 2018–2019
Published in PloS one (28-05-2021)“…Dengue is an endemic disease in Colombia. Norte de Santander is a region on the border of Colombia and Venezuela and has reported the co-circulation and…”
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Compuestos sintéticos del tipo de estirilquinolinas con actividades leishmanicida y citotóxica
Published in Biomédica (01-12-2014)“…Introducción. La leishmaniasis es uno de los principales problemas de salud pública en muchos países, entre ellos, Colombia. Su tratamiento presenta…”
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Actividad tripanocida y citotóxica de extractos de plantas colombianas
Published in Biomédica (01-12-2011)“…Introducción. El tratamiento de la enfermedad de Chagas está basado en sólo dos medicamentos de eficacia limitada y con importantes efectos colaterales. La…”
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The Akt-like kinase of Leishmania panamensis: As a new molecular target for drug discovery
Published in Acta tropica (01-01-2018)“…Schematic model of the putative action of the Lp-RAC/Akt-like protein in response to death and survival in Leishmania panamensis under cell stress conditions…”
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Synthesis of high crystallinity biphasic calcium phosphates/gold nanoparticles composites by solution combustion method with antimicrobial response
Published in Boletín de la Sociedad Española de Cerámica y Vidrio (1983) (01-09-2022)“…Calcium phosphates are biomaterials widely used in bone tissue engineering. In recent years, the alternative of obtaining these materials with antimicrobial…”
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Processing, characterization and biological testing of electrochemically modified titanium for dental implants
Published in Revista Facultad de Ingeniería (31-01-2014)“…Biomedical applications of titanium and its alloys are possible due to their suitable characteristics for bone replacement, including good mechanical…”
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Desarrollo de la industria de aleaciones de magnesio en Colombia - Una oportunidad
Published in Dyna (Medellín, Colombia) (01-12-2017)“…Dentro de los materiales que más avance han tenido en las últimas décadas, se encuentran el magnesio y sus aleaciones, cuyo volumen de producción mundial se ha…”
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Procesamiento, caracterización y ensayos biológicos de titanio modificado electroquímicamente para implantes dentales
Published in Revista Facultad de Ingeniería (01-01-2013)“…Las aplicaciones biomédicas del titanio y sus aleaciones son posibles debido a que éste material posee características deseables para el reemplazo de huesos,…”
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Eficacia y tolerancia de la pentamidina en el tratamiento de la leishmaniasis cutánea producida por Leishmania (V.) panamensis en Colombia
Published in Biomédica (01-10-2006)“…Introducción. El tratamiento de elección de la leishmaniasis cutánea es el antimonio pentavalente con una eficacia cercana al 85%; sin embargo, debido a los…”
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Las células de Langerhans en la inmunidad a leishmaniasis
Published in Biomédica (01-09-2004)“…En la respuesta inmune a parásitos del género Leishmania influyen múltiples factores entre los que se encuentran no sólo los relacionados con el parásito sino…”
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Leishmaniosis cutánea en Colombia y género
Published in Cadernos de saúde pública (2001)“…En Colombia, tradicionalmente se ha visto la leishmaniosis como un problema de Salud Pública para hombres adultos dado que se considera que la transmisión es…”
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Styrylquinolines-type synthetic compounds with leishmanicidal and cytotoxic activities
Published in Biomédica (01-10-2014)“…Leishmaniasis is a major public health problem faced by many countries, including Colombia. Its treatment has limitations such as the toxicity of the drugs…”
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Compuestos sintéticos tipo estirilquinolinas con actividades leishmanicida y citotóxica
Published in Biomédica (15-08-2014)Get full text
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Actividad citotóxica y leishmanicida in vitro del aceite esencial de manzanilla (Matricaria chamomilla)
Published in Revista colombiana de ciencias químico-farmacéuticas (01-07-2008)“…Este estudio describe la evaluación de las actividades citotóxica y leishmanicida del aceite esencial de Matricaria chamomilla, una planta conocida como…”
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