Search Results - "Robison, W G"

Targeted Disruption of the Mouse α A-crystallin Gene Induces Cataract and Cytoplasmic Inclusion Bodies Containing the Small Heat Shock Protein α B-crystallin by Brady, James P., Garland, Donita, Duglas-Tabor, Yvonne, Robinson, W. Gerald, Groome, Anne, Wawrousek, Eric F.

“…α A-crystallin (α A) and α B-crystallin (α B) are among the predominant proteins of the vertebrate eye lens. In vitro, the α -crystallins, which are isolated…”
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Progesterone induces side-branching of the ductal epithelium in the mammary glands of peripubertal mice by Atwood, CS, Hovey, RC, Glover, JP, Chepko, G, Ginsburg, E, Robison, WG, Vonderhaar, BK

“…Development of the functional secretory epithelium in the mammary gland of the female mouse requires the elongation of the anlage through the mammary fat pad…”
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Effects of chronic systemic administration of basic fibroblast growth factor on collateral development in the canine heart by LAZAROUS, D. F, SCHEINOWITZ, M, UNGER, E. F, SHOU, M, HODGE, E, SHARMINI RAJANAYAGAM, M. A, HUNGSBERGER, S, ROBISON, W. G, STIBER, J. A, CORREA, R, EPSTEIN, S. E

“…Recently we reported that intracoronary administration of basic fibroblast growth factor (bFGF), a potent angiogenic peptide, increases collateral blood flow…”
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Omega -crystallin of the scallop lens. A dimeric aldehyde dehydrogenase class 1/2 enzyme-crystallin by Piatigorsky, J, Kozmik, Z, Horwitz, J, Ding, L, Carosa, E, Robison, Jr, W G, Steinbach, P J, Tamm, E R

“…While many of the diverse crystallins of the transparent lens of vertebrates are related or identical to metabolic enzymes, much less is known about the lens…”
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Anti-Glycated Albumin Therapy Ameliorates Early Retinal Microvascular Pathology in db/db Mice by Clements, Rex S, Robison, W.Gerald, Cohen, Margo P

“…Hyperglycemia plays a primary causal role in the early vascular damage leading to diabetic retinopathy, but the intermediate biochemical mechanisms involved…”
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Diabetic-like retinopathy in rats prevented with an aldose reductase inhibitor by Robison, WG, Jr, Nagata, M, Laver, N, Hohman, TC, Kinoshita, JH

“…The earliest histopathologic signs of diabetic retinopathy include selective loss of intramural pericytes and thickening of capillary basement membranes…”
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Sorbinil prevention of diabetic-like retinopathy in the galactose-fed rat model by Robison, WG, Jr, Laver, NM, Jacot, JL, Glover, JP

“…To determine if the retinal microangiopathies of the galactose-fed rat model of diabetic retinopathy can be prevented with the aldose reductase inhibitor…”
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Diabetic-like retinopathy: early and late intervention therapies in galactose-fed rats by Robison, WG, Jr, Jacot, JL, Glover, JP, Basso, MD, Hohman, TC

“…To determine whether the diabetic-like thickening of retinal capillary basement membrane (RCBM) that develops in the galactose-fed rat model of diabetic ocular…”
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Role of small GTP-binding proteins in lovastatin-induced cataracts by Rao, PV, Robison, WG, Jr, Bettelheim, F, Lin, LR, Reddy, VN, Zigler, JS, Jr

“…To investigate the biochemical mechanisms involved in the cataract induced by lovastatin, a commonly used cholesterol-lowering agent. The effects of lovastatin…”
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Retinal Capillaries: Basement Membrane Thickening by Galactosemia Prevented with Aldose Reductase Inhibitor by Robison, W. Gerald, Kador, Peter F., Kinoshita, Jin H.

“…A twofold thickening of capillary basement membranes of rat retinas resulting from dietary galactose was prevented by sorbinil, an inhibitor of aldose…”
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The pharmacology of aldose reductase inhibitors by Kador, P F, Robison, Jr, W G, Kinoshita, J H

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The role of lens epithelium in sugar cataract formation by Robison, Jr, W G, Houlder, N, Kinoshita, J H

“…Previous evidence has shown clearly that sugar cataract formation results from unusually high intracellular levels of polyol. Documentation of polyol-related…”
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Novel procedures for isolating intact retinal vascular beds from diabetic humans and animal models by Laver, NM, Robison, WG, Jr, Pfeffer, BA

“…To improve the 30-year-old "trypsin digestion" procedure for isolation of the complete retinal vasculature, which, in its time, was a revolutionary advance…”
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Diabetic retinopathy: galactose-fed rat model by Robison, Jr, W G

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Intervention with the aldose reductase inhibitor, tolrestat, in renal and retinal lesions of streptozotocin-diabetic rats by MCCALEB, M. L, MCKEAN, M. L, HOHMAN, T. C, ROBISON, W. G

“…The progressive increase in urinary albumin excretion, which precedes the development of diabetic nephropathy, can be prevented in diabetic rats if the aldose…”
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Efficacy of treatment after measurable diabeticlike retinopathy in galactose-fed rats by Robison, WG, Jr, Laver, NM, Jacot, JL, Chandler, ML, York, BM, Glover, JP

“…To determine whether the diabeticlike retinal microangiopathies of the galactose-fed rat model could be ameliorated if intervention by withdrawal of the…”
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Aldose reductase and pericyte-endothelial cell contacts in retina and optic nerve [published erratum appears in Invest Ophthalmol Vis Sci 1990 Apr;31(4):782-3] by Robison, WG, Jr, Nagata, M, Tillis, TN, Laver, N, Kinoshita, JH

“…Normally, direct contacts between pericytes and endothelial cells occur frequently in both retinal and optic nerve capillaries. The contacts are made through…”
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Diabetic-like corneal sensitivity loss in galactose-fed rats ameliorated with aldose reductase inhibitors by Jacot, J L, Hosotani, H, Glover, J P, Lois, N, Robison, Jr, W G

“…This study investigated whether diabetic-like corneal sensory deficits occur in the galactose-fed rat model of diabetic ocular complications and if such…”
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Evidence of cell loss from the rat retina during senescence by Katz, M L, Robison, Jr, W G

“…In order to determine whether neuronal cell death in the retina accompanies senescence, retinas from pigmented ACI rats of various ages were analysed for…”
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Diabetes-related histopathologies of the rat retina prevented with an aldose reductase inhibitor by Robison, Jr, W G, Tillis, T N, Laver, N, Kinoshita, J H

“…Recent evidence obtained from both galactosemic dogs and rats indicated that aldose reductase inhibitors could prevent several capillary lesions which were…”
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