Search Results - "Robison, J A"

Emerging role of CaMKII in neuropsychiatric disease by Robison, A.J

“…Highlights • Recent evidence for CaMKII dysregulation in psychiatric diseases is reviewed. • Changes in postsynaptic structure and function appear to be…”
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Sex Differences in Major Depressive Disorder (MDD) and Preclinical Animal Models for the Study of Depression by Williams, Elizabeth S, Mazei-Robison, Michelle, Robison, A J

“…Depression and related mood disorders constitute an enormous burden on health, quality of life, and the global economy, and women have roughly twice the…”
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Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation by Kennedy, Pamela J, Feng, Jian, Robison, A J, Maze, Ian, Badimon, Ana, Mouzon, Ezekiell, Chaudhury, Dipesh, Damez-Werno, Diane M, Haggarty, Stephen J, Han, Ming-Hu, Bassel-Duby, Rhonda, Olson, Eric N, Nestler, Eric J

“…The authors show that reducing histone deacetylase 1 expression or activity in the nucleus accumbens increases global levels of histone acetylation but also…”
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Fluoxetine Epigenetically Alters the CaMKIIα Promoter in Nucleus Accumbens to Regulate ΔFosB Binding and Antidepressant Effects by ROBISON, A. J, VIALOU, Vincent, NESTLER, Eric J, SUN, Hao-Sheng, LABONTE, Benoit, GOLDEN, Sam A, DIAS, Caroline, TURECKI, Gustavo, TAMMINGA, Carol, RUSSO, Scott, MAZEI-ROBISON, Michelle

“…Chronic social defeat stress in mice produces a susceptible phenotype characterized by several behavioral abnormalities consistent with human depression that…”
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Comparison of chronic physical and emotional social defeat stress effects on mesocorticolimbic circuit activation and voluntary consumption of morphine by Cooper, S. E., Kechner, M., Caraballo-Pérez, D., Kaska, S., Robison, A. J., Mazei-Robison, M. S.

“…Chronic social defeat stress (CSDS) is a well-established rodent model of depression that induces persistent social avoidance. CSDS triggers molecular…”
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Epigenetic Regulation of Hippocampal Fosb Expression Controls Behavioral Responses to Cocaine by Gajewski, Paula A, Eagle, Andrew L, Williams, Elizabeth S, Manning, Claire E, Lynch, Haley, McCornack, Colin, Maze, Ian, Heller, Elizabeth A, Robison, A J

“…Drug addiction results in part from maladaptive learning, including the formation of strong associations between the drug and the circumstances of consumption…”
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Time to drink: Activating lateral hypothalamic area neurotensin neurons promotes intake of fluid over food in a time-dependent manner by Kurt, Gizem, Kodur, Nandan, Quiles, Cristina Rivera, Reynolds, Chelsea, Eagle, Andrew, Mayer, Tom, Brown, Juliette, Makela, Anna, Bugescu, Raluca, Seo, Harim Delgado, Carroll, Quinn E, Daniels, Derek, Robison, A.J., Mazei-Robison, Michelle, Leinninger, Gina

“…•In mice, LHANts neurons are positioned to coordinate feeding and drinking.•During the light cycle, activating LHANts neurons biases fluid over food intake.•In…”
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Genetic inhibition of CaMKII in dorsal striatal medium spiny neurons reduces functional excitatory synapses and enhances intrinsic excitability by Klug, Jason R, Mathur, Brian N, Kash, Thomas L, Wang, Hui-Dong, Matthews, Robert T, Robison, A J, Anderson, Mark E, Deutch, Ariel Y, Lovinger, David M, Colbran, Roger J, Winder, Danny G

“…Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is abundant in striatal medium spiny neurons (MSNs). CaMKII is dynamically regulated by changes in…”
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Reward Circuitry in Addiction by Cooper, Sarah, Robison, A. J., Mazei-Robison, Michelle S.

“…Understanding the brain circuitry that underlies reward is critical to improve treatment for many common health issues, including obesity, depression, and…”
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Commentary: Untangling the structural and enzymatic roles of CaMKII at the synapse by Anderson, Daniela, Robison, A.J.

“…[Display omitted]…”
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Calmodulin acetylation: A modification to remember by Sugimoto, Chiho, Robison, A.J.

“…The formation of new memories appears to require alterations in the shape and strength of synapses within the hippocampus, yet our knowledge of the molecular…”
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Demographic and mortality analysis of hospitalized children at a referral hospital in Addis Ababa, Ethiopia by Bohn, J A, Kassaye, B M, Record, D, Chou, B C, Kraft, I L, Purdy, J C, Hilton, K A, Miller, D A, Getachew, S, Addissie, A, Robison, J A

“…Global childhood mortality rates remain high. Millennium Development Goal 4 focused efforts on reducing rates by two-thirds between 1990 and 2015. In Ethiopia,…”
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Cognition and Reward Circuits in Schizophrenia: Synergistic, Not Separate by Robison, A.J., Thakkar, Katharine N., Diwadkar, Vaibhav A.

“…Schizophrenia has been studied from the perspective of cognitive or reward-related impairments, yet it cannot be wholly related to one or the other process and…”
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An miRNA with a major impact on stress by Simmons, Sarah Cooper, Robison, A J

“…miRNAs regulate mRNAs, including those important for synapse function in the brain. Mucha and colleagues recently identified a novel miRNA-mRNA interaction in…”
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Multivalent Interactions of Calcium/Calmodulin-dependent Protein Kinase II with the Postsynaptic Density Proteins NR2B, Densin-180, and α-Actinin-2 by Robison, A.J., Bass, Martha A., Jiao, Yuxia, MacMillan, Leigh B., Carmody, Leigh C., Bartlett, Ryan K., Colbran, Roger J.

“…Dendritic calcium/calmodulin-dependent protein kinase II (CaMKII) is dynamically targeted to the synapse. We show that CaMKIIα is associated with the…”
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Developmentally regulated alternative splicing of densin modulates protein-protein interaction and subcellular localization by Jiao, Yuxia, Robison, A.J, Bass, Martha A, Colbran, Roger J

“…Densin is a member of the leucine-rich repeat (LRR) and PDZ domain (LAP) protein family that binds several signaling molecules via its C-terminal domains,…”
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Impacts of sex differences on optogenetic, chemogenetic, and calcium-imaging tools by Cea Salazar, Valentina I., Perez, Melvin D., Robison, A.J., Trainor, Brian C.

“…Technical innovation in neuroscience introduced powerful tools for measuring and manipulating neuronal activity via optical, chemogenetic, and calcium-imaging…”
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Oxidation of calmodulin alters activation and regulation of CaMKII by Robison, A.J., Winder, Danny G., Colbran, Roger J., Bartlett, Ryan K.

“…Increases in reactive oxygen species and mis-regulation of calcium homeostasis are associated with various physiological conditions and disease states…”
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GSK3β in the prefrontal cortex: a molecular handle specific to addiction pathology? by Eagle, Andrew L, Robison, A J

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Persistent ∆FosB expression limits recurrent seizure activity and provides neuroprotection in the dentate gyrus of APP mice by Stephens, Gabriel S., Park, Jin, Eagle, Andrew, You, Jason, Silva-Pérez, Manuel, Fu, Chia-Hsuan, Choi, Sumin, Romain, Corey P. St, Sugimoto, Chiho, Buffington, Shelly A., Zheng, Yi, Costa-Mattioli, Mauro, Liu, Yin, Robison, A.J., Chin, Jeannie

“…Recurrent seizures lead to accumulation of the activity-dependent transcription factor ∆FosB in hippocampal dentate granule cells in both mouse models of…”
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