Search Results - "Robison, Amanda"

Antiviral responses in a Jamaican fruit bat intestinal organoid model of SARS-CoV-2 infection by Hashimi, Marziah, Sebrell, T. Andrew, Hedges, Jodi F., Snyder, Deann, Lyon, Katrina N., Byrum, Stephanie D., Mackintosh, Samuel G., Crowley, Dan, Cherne, Michelle D., Skwarchuk, David, Robison, Amanda, Sidar, Barkan, Kunze, Anja, Loveday, Emma K., Taylor, Matthew P., Chang, Connie B., Wilking, James N., Walk, Seth T., Schountz, Tony, Jutila, Mark A., Bimczok, Diane

“…Bats are natural reservoirs for several zoonotic viruses, potentially due to an enhanced capacity to control viral infection. However, the mechanisms of…”
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An ADAM17-Neutralizing Antibody Reduces Inflammation and Mortality While Increasing Viral Burden in a COVID-19 Mouse Model by Hedges, Jodi F., Snyder, Deann T., Robison, Amanda, Grifka-Walk, Heather M., Blackwell, Karlin, Shepardson, Kelly, Kominsky, Douglas, Rynda-Apple, Agnieszka, Walcheck, Bruce, Jutila, Mark A.

“…Angiotensin Converting Enzyme 2 (ACE2) is the primary cell entry receptor for SARS-CoV and SARS-CoV-2 viruses. A disintegrin and metalloproteinase 17 (ADAM17)…”
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Effect of Inactivation Methods on SARS-CoV-2 Virion Protein and Structure by Loveday, Emma K, Hain, Kyle S, Kochetkova, Irina, Hedges, Jodi F, Robison, Amanda, Snyder, Deann T, Brumfield, Susan K, Young, Mark J, Jutila, Mark A, Chang, Connie B, Taylor, Matthew P

“…The risk posed by Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2) dictates that live-virus research is conducted in a biosafety level 3 (BSL3)…”
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A TLR4 agonist liposome formulation effectively stimulates innate immunity and enhances protection from bacterial infection by Hedges, Jodi F., Snyder, Deann T., Robison, Amanda, Thompson, Macy A., Aspelin, Klara, Plewa, Jack, Baldridge, Jory, Jutila, Mark A.

“…Stimulation of innate immunity can protect against infectious insult and could be used in combination with other therapies. Since antibiotic resistance is an…”
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Flagella overexpression attenuates Salmonella pathogenesis by Yang, Xinghong, Thornburg, Theresa, Suo, Zhiyong, Jun, SangMu, Robison, Amanda, Li, Jinquan, Lim, Timothy, Cao, Ling, Hoyt, Teri, Avci, Recep, Pascual, David W

“…Flagella are cell surface appendages involved in a number of bacterial behaviors, such as motility, biofilm formation, and chemotaxis. Despite these important…”
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Titers, Prevalence, and Duration of SARS-CoV-2 Antibodies in a Local COVID-19 Outbreak and Following Vaccination by Hedges, Jodi F., Thompson, Macy A., Snyder, Deann T., Robison, Amanda, Taylor, Matthew P., Jutila, Mark A.

“…Information concerning the development of neutralizing antibodies and their duration will be critical to establishing herd immunity for COVID-19. We sought to…”
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Effect of oenothein B, a cyclic dimeric ellagitannin isolated from Epilobium angustifolium , on the antiviral responses of innate lymphocytes. (P4365) by Ramstead, Andrew, Schepetkin, Igor, Robison, Amanda, Quinn, Mark, Jutila, Mark

“…Oenothein B is an ellagitannin isolated from the Epilobium angustifolium plant, which has been shown to have immunomodulatory properties. This compound is…”
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Recombinant Salmonella vaccination technology and its application to human bacterial pathogens by Zhang, Song, Walters, Nancy, Cao, Ling, Robison, Amanda, Yang, Xinghong

“…Salmonella enterica is a Gram-negative intracellular bacterial pathogen which causes salmonellosis in humans and animals. During the past several decades,…”
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Less may be more for Brucella bacteriophage therapy due to immune suppressive effects by Hedges, Jodi F, Robison, Amanda, Snyder, Deann Teresa, Plewa, Jack, Jutila, Mark A

“…We are studying the applicability of Brucella-specific phages to counter brucellosis. With antibiotic resistance on the rise and new realizations concerning…”
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Titers, prevalence and duration of SARS-CoV-2 antibodies in two waves of a local COVID-19 outbreak by Hedges, Jodi F, Thomspon, Macy A., Snyder, Deann T., Robison, Amanda, Taylor, Matthew P., Jutila, Mark A

“…Information concerning the development of neutralizing antibodies and their duration will be critical to establishing herd immunity for COVID-19. We sought to…”
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ADAM-17 protease promotes inflammation and mortality while decreasing viral burden in a COVID-19 mouse model by Hedges, Jodi F, Snyder, Deann T., Robison, Amanda, Walk, Heather, Havlak, Karlin, Shepardson, Kelly, Kominsky, Douglas, Rynda-Apple, Agnieszka, Walcheck, Bruce, Jutila, Mark A.

“…Angiotensin Converting Enzyme 2 (ACE2) is the primary cell entry receptor for SARS-CoV-1 and SARS-CoV-2 viruses. A disintegrin and metalloproteinase 17…”
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Nasal vaccination of β7 integrin‐deficient mice retains elevated IgA immunity by Maślanka, Tomasz, Clapp, Beata, Hoffman, Carol, Robison, Amanda, Gregorczyk, Izabela, Pascual, David W

“…Understanding the migration of lymphocytes to nonintestinal mucosal sites is fundamental to developing mucosal vaccination strategies. Studies have shown that…”
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Expression of human TLR4/MD-2 directs an early innate immune response associated with modest increase in bacterial burden during Coxiella burnetii infection by Hedges, Jodi F, Robison, Amanda, Snyder, Deann Teresa, Hajjar, Adeline M., Jutila, Mark A

“…Human and mouse TLR4 molecules respond differently to hypo-acylated LPS. The LPS of Coxiella burnetii is hypo-acylated, heavily glycosylated and known to cause…”
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Functional SLC11A1 (NRAMP1) enhances protection from Coxiella burnetii infection by Hedges, Jodi F, Robison, Amanda, Kimmel, Emily, Jutila, Mark A.

“…SLC11A1 is a divalent ion transporter formerly known as the natural resistance-associated macrophage protein (NRAMP1). Also known as the Bcg/Lsh/Ity locus,…”
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Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Infection in a Bat Gastrointestinal Organoid Model by Hashimi, Marziah, Sebrell, Thomas, Hedges, Jodi, Snyder, Deann Teresa, Lyon, Katrina, Cherne, Michelle D, Robison, Amanda, Sidar, Barkan, Wilking, James, Walk, Seth, Schountz, Tony, Jutila, Mark A., Bimczok, Diane

“…The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19, is thought to have originated in bats, since multiple…”
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Consumption of plant-derived agonists that enhance NK cell activity is beneficial in infection- and DSS- induced colitis (IRC8P.486) by Snyder, Deann, Hedges, Jodi, Robison, Amanda, Kimmel, Emily, Jutila, Mark

“…Inflammatory bowel disease (IBD) is characterized by chronic, relapsing inflammation for which there is no known cure and limited treatment and preventative…”
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Type I IFN signaling promotes Coxiella burnetii infection (INM8P.446) by Hedges, Jodi, Robison, Amanda, Christensen, Kelly, Ramstead, Andrew, Jutila, Mark

“…Coxiella burnetii is an obligate intracellular pathogen and the cause of Q fever. The strain Nine Mile Phase I (NMI) is virulent whereas a laboratory passaged…”
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Expression of human hTLR4/MD2 in vivo in mice alters infection with C. burnetii by Robison, Amanda, Hedges, Jodi F, Kimmel, Emily, Hajjar, Adeline M., Jutila, Mark A.

“…Human and mouse TLR4/MD2 molecules respond differently to specific types of LPS. Their response to normally acylated LPS is similar, but they respond…”
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Type I Interferon Counters or Promotes Coxiella burnetii Replication Dependent on Tissue by Hedges, Jodi F, Robison, Amanda, Kimmel, Emily, Christensen, Kelly, Lucas, Erin, Ramstead, Andrew, Jutila, Mark A

“…Coxiella burnetii is an intracellular pathogen and the cause of Q fever. Gamma interferon (IFN-γ) is critical for host protection from infection, but a role…”
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Expression of human TLR4/myeloid differentiation factor 2 directs an early innate immune response associated with modest increases in bacterial burden during infection by Amanda Robison, Deann T Snyder, Kelly Christensen, Emily Kimmel, Adeline M Hajjar, Mark A Jutila, Jodi F Hedges

“…Human TLR4 (hTLR4) and mouse TLR4 molecules respond differently to hypo-acylated LPS. The LPS of Coxiella burnetii is hypo-acylated and heavily glycosylated…”
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