Search Results - "Robinson, Shawn W"
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Implementation of pharmacogenetics: The University of Maryland personalized anti-platelet pharmacogenetics program
Published in American journal of medical genetics. Part C, Seminars in medical genetics (01-03-2014)“…Despite a substantial evidence base, implementation of pharmacogenetics into routine patient care has been slow due to a number of non‐trivial practical…”
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Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention
Published in JACC. Cardiovascular interventions (22-01-2018)“…This multicenter pragmatic investigation assessed outcomes following clinical implementation of CYP2C19 genotype–guided antiplatelet therapy after percutaneous…”
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Frailty Measures of Patient-reported Activity and Fatigue May Predict 1-year Outcomes in Ambulatory Advanced Heart Failure: A Report From the REVIVAL Registry
Published in Journal of cardiac failure (01-05-2022)“…The Fried Frailty Phenotype predicts adverse outcomes in geriatric populations, but has not been well-studied in advanced heart failure (HF). The Registry…”
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Comorbid Conditions and Health-Related Quality of Life in Ambulatory Heart Failure Patients: REVIVAL (Registry Evaluation of Vital Information for VADs in Ambulatory Life REVIVAL)
Published in Circulation. Heart failure (01-05-2020)“…Patients with heart failure (HF) often have multiple chronic conditions that may impact health-related quality of life (HRQOL) despite HF therapy. We sought to…”
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A Genome-Wide Association Study of Idiopathic Dilated Cardiomyopathy in African Americans
Published in Journal of personalized medicine (26-02-2018)“…Idiopathic dilated cardiomyopathy (IDC) is the most common form of non-ischemic chronic heart failure. Despite the higher prevalence of IDC in African…”
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A New Clinically Applicable Measure of Functional Status in Patients With Heart Failure: The 60-Foot Walk Test
Published in JACC. Heart failure (01-06-2017)“…This study reports the development and predictive value of the 60-foot walk test (60ftWT), a brief functional status measure for patients with heart failure…”
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An Antisense Oligonucleotide Against H1 Inhibits the Classical Sodium Current but not ICa(TTX) in Rat Ventricular Cells
Published in The Journal of physiology (01-03-2003)“…I Ca(TTX) is a sodium current component, functionally distinct from the main body of sodium current, seen in cardiac and other cells. To determine if I Ca(TTX)…”
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Factors Associated with Chronic Worsening of Renal Function in Stable Heart Failure Patients in an Ambulatory Setting
Published in Journal of cardiac failure (01-08-2012)Get full text
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A New Clinically Applicable Measure of Functional Status in Patients With Heart Failure
Published in JACC. Heart failure (01-06-2017)“…Abstract Objectives This study reports the development and predictive value of the 60-foot walk test (60ftWT), a brief functional status measure for patients…”
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Hypertrophy-Associated Polymorphisms Ascertained in a Founder Cohort Applied to Heart Failure Risk and Mortality
Published in Clinical and translational science (01-02-2011)“…A three‐stage approach was undertaken using genome‐wide, case‐control, and case‐only association studies to identify genetic variants associated with heart…”
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Sex, Digitalis, and the Sodium Pump
Published in Molecular interventions (01-03-2003)“…Foxglove and its constituents therapeutic agent digitalis have been used for centuries for the treatment of heart failure. All digitalis-like cardiotonic…”
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The Association of Sodium Intake and Objective and Subjective Indicators of Heart Failure Severity
Published in Journal of cardiac failure (2011)Get full text
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Stimulation of Na,K-ATPase by low potassium requires reactive oxygen species
Published in American Journal of Physiology: Cell Physiology (01-08-2003)“…The signaling pathway that transduces the stimulatory effect of low K+ on the biosynthesis of Na,K-ATPase remains largely unknown. The present study was…”
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The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Overcoming Challenges of Real-World Implementation
Published in Clinical pharmacology and therapeutics (01-08-2013)“…The pace of discovery of potentially actionable pharmacogenetic variants has increased dramatically in recent years. However, the implementation of this new…”
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Abstract 16631: Frailty Phenotype is Associated With 1-Year Outcomes in Ambulatory Advanced Heart Failure: A Report From the REVIVAL Registry
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionThe Fried Frailty Phenotype (FFP), defined by weakness, slowness, inactivity, exhaustion and weight loss, predicts adverse outcomes in geriatric…”
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Abstract 17088: Role of Caregiver Participation in Outcomes for Patients With Advanced Ambulatory Heart Failure: An Analysis of the Revival Registry
Published in Circulation (New York, N.Y.) (06-11-2018)“…IntroductionAdvanced HF requires tremendous resources, and family caregivers generate significant health related cost-savings. Earlier work in the REVIVAL…”
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Comorbid Conditions and Health-related Quality of Life in Ambulatory Heart Failure Patients: A Report from REVIVAL
Published in Circulation. Heart failure (01-05-2020)Get full text
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