Search Results - "Robinson, Phyllis R."
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Shedding new light on opsin evolution
Published in Proceedings of the Royal Society. B, Biological sciences (07-01-2012)“…Opsin proteins are essential molecules in mediating the ability of animals to detect and use light for diverse biological functions. Therefore, understanding…”
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2
A visual circuit uses complementary mechanisms to support transient and sustained pupil constriction
Published in eLife (26-09-2016)“…Rapid and stable control of pupil size in response to light is critical for vision, but the neural coding mechanisms remain unclear. Here, we investigated the…”
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Spectral tuning and deactivation kinetics of marine mammal melanopsins
Published in PloS one (15-10-2021)“…In mammals, the photopigment melanopsin (Opn4) is found in a subset of retinal ganglion cells that serve light detection for circadian photoentrainment and…”
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Melanopsin Carboxy-terminus phosphorylation plasticity and bulk negative charge, not strict site specificity, achieves phototransduction deactivation
Published in PloS one (01-04-2020)“…Melanopsin is a visual pigment expressed in a small subset of ganglion cells in the mammalian retina known as intrinsically photosensitive retinal ganglion…”
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Unexpected diversity and photoperiod dependence of the zebrafish melanopsin system
Published in PloS one (22-09-2011)“…Animals have evolved specialized photoreceptors in the retina and in extraocular tissues that allow them to measure light changes in their environment. In…”
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β-Arrestin-dependent deactivation of mouse melanopsin
Published in PloS one (17-11-2014)“…In mammals, the expression of the unusual visual pigment, melanopsin, is restricted to a small subset of intrinsically photosensitive retinal ganglion cells…”
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The C-Terminus and Third Cytoplasmic Loop Cooperatively Activate Mouse Melanopsin Phototransduction
Published in Biophysical journal (21-07-2020)“…Melanopsin, an atypical vertebrate visual pigment, mediates non-image-forming light responses including circadian photoentrainment and pupillary light reflexes…”
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Spectral tuning and evolution of primate short-wavelength-sensitive visual pigments
Published in Proceedings of the Royal Society. B, Biological sciences (22-01-2012)“…The peak sensitivities (λmax) of the short-wavelength-sensitive-1 (SWS1) pigments in mammals range from the ultraviolet (UV) (360–400 nm) to the violet…”
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C-terminal phosphorylation regulates the kinetics of a subset of melanopsin-mediated behaviors in mice
Published in Proceedings of the National Academy of Sciences - PNAS (07-03-2017)“…Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin and mediate several non–image-forming visual functions,…”
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10
Evolution of the cichlid visual palette through ontogenetic subfunctionalization of the opsin gene arrays
Published in Molecular biology and evolution (01-08-2006)“…The evolution of cone opsin genes is characterized by a dynamic process of gene birth and death through gene duplication and loss. However, the forces…”
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Phosphorylation of mouse melanopsin by protein kinase A
Published in PloS one (26-09-2012)“…The visual pigment melanopsin is expressed in intrinsically photosensitive retinal ganglion cells (ipRGCs) in the mammalian retina, where it is involved in…”
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12
Identification of Critical Phosphorylation Sites on the Carboxy Tail of Melanopsin
Published in Biochemistry (Easton) (29-04-2014)“…Light-activated opsins undergo carboxy-terminal phosphorylation, which contributes to the deactivation of their photoresponse. The photopigment melanopsin…”
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Photochemistry of retinal chromophore in mouse melanopsin
Published in Proceedings of the National Academy of Sciences - PNAS (01-07-2008)“…In mammals, melanopsin is exclusively expressed in intrinsically photosensitive retinal ganglion cells (ipRGCs), which play an important role in circadian…”
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14
Melanopsin Forms a Functional Short-Wavelength Photopigment
Published in Biochemistry (Easton) (11-11-2003)“…Recently, melanopsin has emerged as the leading candidate for the elusive photopigment of the mammalian circadian system. This novel opsin-like protein is…”
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Molecular diversity of visual pigments in Stomatopoda (Crustacea)
Published in Visual neuroscience (01-05-2009)“…Stomatopod crustaceans possess apposition compound eyes that contain more photoreceptor types than any other animal described. While the anatomy and physiology…”
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Melanopsin phototransduction: beyond canonical cascades
Published in Journal of experimental biology (01-12-2021)“…Melanopsin is a visual pigment that is expressed in a small subset of intrinsically photosensitive retinal ganglion cells (ipRGCs). It is involved in…”
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The visual pigments of the West Indian manatee ( Trichechus manatus)
Published in Vision research (Oxford) (01-10-2006)“…Manatees are unique among the fully aquatic marine mammals in that they are herbivorous creatures, with hunting strategies restricted to grazing on…”
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Cone visual pigments of aquatic mammals
Published in Visual neuroscience (01-11-2005)“…It has long been hypothesized that the visual systems of animals are evolutionarily adapted to their visual environment. The entrance many millions of years…”
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The molecular mechanism for the spectral shifts between vertebrate ultraviolet- and violet-sensitive cone visual pigments
Published in Biochemical journal (01-10-2002)“…The short-wave-sensitive (SWS) visual pigments of vertebrate cone photoreceptors are divided into two classes on the basis of molecular identity, SWS1 and…”
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Protein Phosphatase 2A and Clathrin-Mediated Endocytosis Facilitate Robust Melanopsin Light Responses and Resensitization
Published in Investigative ophthalmology & visual science (01-10-2020)“…Intrinsically photosensitive retinal ganglion cells (ipRGCs) that express the visual pigment melanopsin regulate non-image-forming visual tasks, such as…”
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