Search Results - "Robinson, Peter"

Enzymes: principles and biotechnological applications by Robinson, Peter K

“…Enzymes are biological catalysts (also known as biocatalysts) that speed up biochemical reactions in living organisms, and which can be extracted from cells…”
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Deep phenotyping for precision medicine by Robinson, Peter N.

“…In medical contexts, the word “phenotype” is used to refer to some deviation from normal morphology, physiology, or behavior. The analysis of phenotype plays a…”
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Phenolyzer: phenotype-based prioritization of candidate genes for human diseases by Yang, Hui, Robinson, Peter N, Wang, Kai

“…The Phenolyzer software provides prioritized candidate gene lists based on disease and phenotype terms that are entered by users as free text. Prior biological…”
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Task-Based Language Learning: A Review of Issues by Robinson, Peter

“…Theoretically motivated, empirical research into task‐based language learning has been prompted by proposals for task‐based language teaching. In this review I…”
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Classification, Ontology, and Precision Medicine by Haendel, Melissa A, Chute, Christopher G, Robinson, Peter N

“…Data-organizing methods have been in place for centuries, but very large data sets have come into being relatively recently. The authors describe…”
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A Whole-Genome Analysis Framework for Effective Identification of Pathogenic Regulatory Variants in Mendelian Disease by Smedley, Damian, Schubach, Max, Jacobsen, Julius O.B., Köhler, Sebastian, Zemojtel, Tomasz, Spielmann, Malte, Jäger, Marten, Hochheiser, Harry, Washington, Nicole L., McMurry, Julie A., Haendel, Melissa A., Mungall, Christopher J., Lewis, Suzanna E., Groza, Tudor, Valentini, Giorgio, Robinson, Peter N.

“…The interpretation of non-coding variants still constitutes a major challenge in the application of whole-genome sequencing in Mendelian disease, especially…”
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FABIAN-variant: predicting the effects of DNA variants on transcription factor binding by Steinhaus, Robin, Robinson, Peter N, Seelow, Dominik

“…Abstract While great advances in predicting the effects of coding variants have been made, the assessment of non-coding variants remains challenging. This is…”
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Long-Range Dependent Curve Time Series by Li, Degui, Robinson, Peter M., Shang, Han Lin

“…We introduce methods and theory for functional or curve time series with long-range dependence. The temporal sum of the curve process is shown to be…”
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The dynamic brain: from spiking neurons to neural masses and cortical fields by Deco, Gustavo, Jirsa, Viktor K, Robinson, Peter A, Breakspear, Michael, Friston, Karl

“…The cortex is a complex system, characterized by its dynamics and architecture, which underlie many functions such as action, perception, learning, language,…”
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Phenotype ontologies and cross-species analysis for translational research by Robinson, Peter N, Webber, Caleb

“…The use of model organisms as tools for the investigation of human genetic variation has significantly and rapidly advanced our understanding of the…”
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Pervasive and CpG-dependent promoter-like characteristics of transcribed enhancers by Steinhaus, Robin, Gonzalez, Tonatiuh, Seelow, Dominik, Robinson, Peter N

“…The temporal and spatial expression of genes is controlled by promoters and enhancers. Findings obtained over the last decade that not only promoters but also…”
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Geometric constraints on human brain function by Pang, James C., Aquino, Kevin M., Oldehinkel, Marianne, Robinson, Peter A., Fulcher, Ben D., Breakspear, Michael, Fornito, Alex

“…The anatomy of the brain necessarily constrains its function, but precisely how remains unclear. The classical and dominant paradigm in neuroscience is that…”
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Deep phenotyping: symptom annotation made simple with SAMS by Steinhaus, Robin, Proft, Sebastian, Seelow, Evelyn, Schalau, Tobias, Robinson, Peter N, Seelow, Dominik

“…Abstract Precision medicine needs precise phenotypes. The Human Phenotype Ontology (HPO) uses clinical signs instead of diagnoses and has become the standard…”
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The Human Phenotype Ontology in 2021 by Köhler, Sebastian, Gargano, Michael, Matentzoglu, Nicolas, Carmody, Leigh C, Lewis-Smith, David, Vasilevsky, Nicole A, Danis, Daniel, Balagura, Ganna, Baynam, Gareth, Brower, Amy M, Callahan, Tiffany J, Chute, Christopher G, Est, Johanna L, Galer, Peter D, Ganesan, Shiva, Griese, Matthias, Haimel, Matthias, Pazmandi, Julia, Hanauer, Marc, Harris, Nomi L, Hartnett, Michael J, Hastreiter, Maximilian, Hauck, Fabian, He, Yongqun, Jeske, Tim, Kearney, Hugh, Kindle, Gerhard, Klein, Christoph, Knoflach, Katrin, Krause, Roland, Lagorce, David, McMurry, Julie A, Miller, Jillian A, Munoz-Torres, Monica C, Peters, Rebecca L, Rapp, Christina K, Rath, Ana M, Rind, Shahmir A, Rosenberg, Avi Z, Segal, Michael M, Seidel, Markus G, Smedley, Damian, Talmy, Tomer, Thomas, Yarlalu, Wiafe, Samuel A, Xian, Julie, Yüksel, Zafer, Helbig, Ingo, Mungall, Christopher J, Haendel, Melissa A, Robinson, Peter N

“…Abstract The Human Phenotype Ontology (HPO, https://hpo.jax.org) was launched in 2008 to provide a comprehensive logical standard to describe and…”
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Computing Minimal Boolean Models of Gene Regulatory Networks by Karlebach, Guy, Robinson, Peter N

“…Models of gene regulatory networks (GRNs) capture the dynamics of the regulatory processes that occur within the cell as a means to understanding the…”
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Inference on higher-order spatial autoregressive models with increasingly many parameters by Gupta, Abhimanyu, Robinson, Peter M.

“…This paper develops consistency and asymptotic normality of parameter estimates for a higher-order spatial autoregressive model whose order, and number of…”
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Biometric and structural ocular manifestations of Marfan syndrome by Gehle, Petra, Goergen, Barbara, Pilger, Daniel, Ruokonen, Peter, Robinson, Peter N, Salchow, Daniel J

“…To study biometric and structural ocular manifestations of Marfan syndrome (MFS). Observational, retrospective, comparative cohort study in a tertiary referral…”
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Higher-order least squares inference for spatial autoregressions by Rossi, Francesca, Robinson, Peter M.

“…We develop refined inference for spatial regression models with predetermined regressors. The ordinary least squares estimate of the spatial parameter is…”
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Insights into the complementarity of natural disaster insurance purchases and risk reduction behavior by Rufat, Samuel, Robinson, Peter J., Botzen, Wouter J. W.

“…While flooding is the costliest natural disaster risk, public‐sector investments provide incomplete protection. Moreover, individuals are in general reluctant…”
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L1Base 2: more retrotransposition-active LINE-1s, more mammalian genomes by Penzkofer, Tobias, Jäger, Marten, Figlerowicz, Marek, Badge, Richard, Mundlos, Stefan, Robinson, Peter N, Zemojtel, Tomasz

“…LINE-1 (L1) insertions comprise as much as 17% of the human genome sequence, and similar proportions have been recorded for other mammalian species. Given the…”
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