Search Results - "Robinson, Leanne J."
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Ultra-sensitive detection of Plasmodium falciparum by amplification of multi-copy subtelomeric targets
Published in PLoS medicine (01-03-2015)“…Planning and evaluating malaria control strategies relies on accurate definition of parasite prevalence in the population. A large proportion of asymptomatic…”
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Blood-Stage Parasitaemia and Age Determine Plasmodium falciparum and P. vivax Gametocytaemia in Papua New Guinea
Published in PloS one (21-05-2015)“…A better understanding of human-to-mosquito transmission is crucial to control malaria. In order to assess factors associated with gametocyte carriage, 2083…”
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Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children: a randomised placebo-controlled trial and mathematical model
Published in PLoS medicine (01-10-2015)“…The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in…”
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Sensitive and accurate quantification of human malaria parasites using droplet digital PCR (ddPCR)
Published in Scientific reports (16-12-2016)“…Accurate quantification of parasite density in the human host is essential for understanding the biology and pathology of malaria. Semi-quantitative molecular…”
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Mathematical modelling of the impact of expanding levels of malaria control interventions on Plasmodium vivax
Published in Nature communications (17-08-2018)“…Plasmodium vivax poses unique challenges for malaria control and elimination, notably the potential for relapses to maintain transmission in the face of…”
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Decreased bioefficacy of long-lasting insecticidal nets and the resurgence of malaria in Papua New Guinea
Published in Nature communications (20-07-2020)“…Papua New Guinea (PNG) has the highest malaria transmission outside of Africa. Long-lasting insecticidal nets (LLINs) are believed to have helped to reduce…”
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Forest malaria in Cambodia: the occupational and spatial clustering of Plasmodium vivax and Plasmodium falciparum infection risk in a cross-sectional survey in Mondulkiri province, Cambodia
Published in Malaria journal (19-11-2020)“…Abstract Background After a marked reduction in malaria burden in Cambodia over the last decades, case numbers increased again in 2017–2018. In light of the…”
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Insecticide resistance status of Aedes aegypti and Aedes albopictus mosquitoes in Papua New Guinea
Published in Parasites & vectors (03-07-2019)“…Aedes aegypti and Ae. albopictus are important vectors of infectious diseases, especially those caused by arboviruses such as dengue, chikungunya and Zika…”
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Developing sero-diagnostic tests to facilitate Plasmodium vivax Serological Test-and-Treat approaches: modeling the balance between public health impact and overtreatment
Published in BMC medicine (18-03-2022)“…Eliminating Plasmodium vivax will require targeting the hidden liver-stage reservoir of hypnozoites. This necessitates new interventions balancing the benefit…”
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Lessons for improved COVID-19 surveillance from the scale-up of malaria testing strategies
Published in Malaria journal (20-07-2022)“…Effective control of infectious diseases is facilitated by informed decisions that require accurate and timely diagnosis of disease. For malaria, improved…”
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Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and magnitude of response
Published in Infection and immunity (01-02-2015)“…Individuals in areas of Plasmodium falciparum endemicity develop immunity to malaria after repeated exposure. Knowledge of the acquisition and nature of…”
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Community perceptions and acceptability of mass drug administration for the control of neglected tropical diseases in Asia-Pacific countries: A systematic scoping review of qualitative research
Published in PLoS neglected tropical diseases (01-03-2022)“…Preventative chemotherapy and mass drug administration have been identified as effective strategies for the prevention, treatment, control and elimination of…”
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Global, asynchronous partial sweeps at multiple insecticide resistance genes in Aedes mosquitoes
Published in Nature communications (24-07-2024)“…Aedes aegypti (yellow fever mosquito) and Ae. albopictus (Asian tiger mosquito) are globally invasive pests that confer the world’s dengue burden…”
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A comparison of non-magnetic and magnetic beads for measuring IgG antibodies against Plasmodium vivax antigens in a multiplexed bead-based assay using Luminex technology (Bio-Plex 200 or MAGPIX)
Published in PloS one (04-12-2020)“…Multiplexed bead-based assays that use Luminex® xMAP® technology have become popular for measuring antibodies against proteins of interest in many fields,…”
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Identification of the asymptomatic Plasmodium falciparum and Plasmodium vivax gametocyte reservoir under different transmission intensities
Published in PLoS neglected tropical diseases (27-08-2021)“…Background Understanding epidemiological variables affecting gametocyte carriage and density is essential to design interventions that most effectively reduce…”
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Naturally acquired antibody responses to more than 300 Plasmodium vivax proteins in three geographic regions
Published in PLoS neglected tropical diseases (11-09-2017)“…Plasmodium vivax remains an important cause of malaria in South America and the Asia-Pacific. Naturally acquired antibody responses against multiple P. vivax…”
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Insufficient duration of insecticidal efficacy of Yahe ® insecticide-treated nets in Papua New Guinea
Published in Malaria journal (05-06-2024)“…Insecticide-treated nets (ITNs) are the backbone of anti-malarial vector control in Papua New Guinea (PNG). Over recent years the quality and performance of…”
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SNP barcodes provide higher resolution than microsatellite markers to measure Plasmodium vivax population genetics
Published in Malaria journal (20-10-2020)“…Genomic surveillance of malaria parasite populations has the potential to inform control strategies and to monitor the impact of interventions. Barcodes…”
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Co-infection of the four major Plasmodium species: Effects on densities and gametocyte carriage
Published in PLoS neglected tropical diseases (13-09-2022)“…Background Co-infection of the four major species of human malaria parasite Plasmodium falciparum ( Pf ), P . vivax ( Pv ), P . malariae ( Pm ), and P . ovale…”
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Vector composition, abundance, biting patterns and malaria transmission intensity in Madang, Papua New Guinea: assessment after 7 years of an LLIN-based malaria control programme
Published in Malaria journal (05-01-2022)“…A malaria control programme based on distribution of long-lasting insecticidal bed nets (LLINs) and artemisinin combination therapy began in Papua New Guinea…”
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