Search Results - "Robinson, James M"

The complexity and cost of vaccine manufacturing – An overview by Plotkin, Stanley, Robinson, James M, Cunningham, Gerard, Iqbal, Robyn, Larsen, Shannon

“…Abstract As companies, countries, and governments consider investments in vaccine production for routine immunization and outbreak response, understanding the…”
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Estimating the cost of vaccine development against epidemic infectious diseases: a cost minimisation study by Gouglas, Dimitrios, Thanh Le, Tung, Henderson, Klara, Kaloudis, Aristidis, Danielsen, Trygve, Hammersland, Nicholas Caspersen, Robinson, James M, Heaton, Penny M, Røttingen, John-Arne

“…The Coalition for Epidemic Preparedness Innovations was established in 2016, to develop vaccines that can contribute to preparedness for outbreaks of epidemic…”
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A randomized matched-pairs study of feasibility, acceptability, and effectiveness of systems consultation: a novel implementation strategy for adopting clinical guidelines for Opioid prescribing in primary care by Quanbeck, Andrew, Brown, Randall T, Zgierska, Aleksandra E, Jacobson, Nora, Robinson, James M, Johnson, Roberta A, Deyo, Brienna M, Madden, Lynn, Tuan, Wen-Jan, Alagoz, Esra

“…This paper reports on the feasibility, acceptability, and effectiveness of an innovative implementation strategy named "systems consultation" aimed at…”
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Vaccine Development Should Be Polytheistic, Not Monotheistic by Plotkin, Stanley A, Robinson, James M, Fitchett, Joseph R A, Gershburg, Edward

“…Vaccines based on mRNA technology have been tremendously successful, but their properties are not necessarily ideal for all pathogens. There is a risk that…”
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Efficacy of Intratympanic OTO-104 for the Treatment of Ménière's Disease: The Outcome of Three Randomized, Double-Blind, Placebo-Controlled Studies by Phillips, John, Mikulec, Anthony A., Robinson, James M., Skarinsky, David, Anderson, Jeffery J.

“…To determine the efficacy of intratympanic OTO-104 for the treatment of Ménière's disease. Three randomized, double-blind, placebo-controlled, multicenter…”
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Emricasan (IDN‐6556) Lowers Portal Pressure in Patients With Compensated Cirrhosis and Severe Portal Hypertension by Garcia‐Tsao, Guadalupe, Fuchs, Michael, Shiffman, Mitchell, Borg, Brian B., Pyrsopoulos, Nikolaos, Shetty, Kirti, Gallegos‐Orozco, Juan F., Reddy, K. Rajender, Feyssa, Eyob, Chan, Jean L., Yamashita, Mason, Robinson, James M., Spada, Alfred P., Hagerty, David T., Bosch, Jaime

“…Caspases play a central role in apoptosis, inflammation, and fibrosis. They produce hemodynamically active, proinflammatory microparticles that cause…”
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Initial Results from Mobile Low‐Dose Computerized Tomographic Lung Cancer Screening Unit: Improved Outcomes for Underserved Populations by Raghavan, Derek, Wheeler, Mellisa, Doege, Darcy, Doty, John D., Levy, Henri, Dungan, Kia A., Davis, Lauren M., Robinson, James M., Kim, Edward S., Mileham, Kathryn F., Oliver, James, Carrizosa, Daniel

“…Introduction The National Lung Screening Trial (NLST) demonstrated that screening high‐risk patients with low‐dose computed tomography (CT) of the chest…”
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Randomized placebo-controlled trial of emricasan for non-alcoholic steatohepatitis-related cirrhosis with severe portal hypertension by Garcia-Tsao, Guadalupe, Bosch, Jaime, Kayali, Zeid, Harrison, Stephen A., Abdelmalek, Manal F., Lawitz, Eric, Satapathy, Sanjaya K., Ghabril, Marwan, Shiffman, Mitchell L., Younes, Ziad H., Thuluvath, Paul J., Berzigotti, Annalisa, Albillos, Agustin, Robinson, James M., Hagerty, David T., Chan, Jean L., Sanyal, Arun J., Abdelmalek, M., Bhamidimarri, K., Borg, B., Caldwell, S., Fenkel, J., Freilich, B., Fuchs, M., Ghabril, M., Ghalib, R., Gonzalez, S., Gordon, S., Hameed, B., Harrison, S., Kayali, Z., Kemmer, N., Korenblat, K., Lai, M., Landis, C., Lawitz, E., Lee, W., Lidofsky, S., Mena, E., Noureddin, M., Paredes, A., Pyrsopoulos, N., Reddy, R., Rinella, M., Rockey, D., Rodriguez, M., Ryan, M., Sarkar, S., Satapathy, S., Scanga, A., Shiffman, M., Siddiqui, M., Simonetto, D., Syn, W., Thuluvath, P., Vemulapalli, R., Vierling, J., Younes, Z., Albillos, A., Ruiz-Tapiador, J. Arenas, Augustin, S., Calleja, J., Garcia, J. Crespo, Buey, L. Garcia, Garcia-Pagan, J.C., Villanueva, C., Bureau, C., Carbonell, N., Leroy, V., Rautou, P.-E., Heinzow, H., Schiefke, I., Zipprich, A., Berzigotti, A., Muellhaupt, B.

“…Emricasan, an oral pan-caspase inhibitor, decreased portal pressure in experimental cirrhosis and in an open-label study in patients with cirrhosis and severe…”
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Emricasan Improves Liver Function in Patients With Cirrhosis and High Model for End-Stage Liver Disease Scores Compared With Placebo by Frenette, Catherine T., Morelli, Giuseppe, Shiffman, Mitchell L., Frederick, R. Todd, Rubin, Raymond A., Fallon, Michael B., Cheng, Jason T., Cave, Matt, Khaderi, Saira A., Massoud, Omar, Pyrsopoulos, Nikolaos, Park, James S., Robinson, James M., Yamashita, Mason, Spada, Alfred P., Chan, Jean L., Hagerty, David T.

“…Caspase-mediated apoptosis and inflammation contribute to progression of liver disease. Emricasan is a pan-caspase inhibitor that reduced serum markers of…”
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A randomized, double-blind, placebo-controlled phase 2 study of intratympanic OTO-313 in patients with moderate to severe subjective tinnitus by Searchfield, Grant D., Robinson, James M., Skarinsky, David, Wang, Yiwei, Anderson, Jeffery J.

“…Purpose This was a randomized, double-blind, placebo-controlled Phase 2 study to evaluate the efficacy and safety of intratympanic OTO-313 in patients with…”
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Intratympanic Administration of OTO-313 Reduces Tinnitus in Patients With Moderate to Severe, Persistent Tinnitus: A Phase 1/2 Study by Maxwell, Kenneth S., Robinson, James M., Hoffmann, Ines, Hou, Huiying J., Searchfield, Grant, Baguley, David M., McMurry, Gordon, Piu, Fabrice, Anderson, Jeffery J.

“…To evaluate the safety and exploratory efficacy of intratympanic administration of OTO-313 in patients with tinnitus. Single intratympanic injection of OTO-313…”
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Multicenter, Double‐Blind, Randomized Trial of Emricasan in Hepatitis C–Treated Liver Transplant Recipients With Residual Fibrosis or Cirrhosis by Weinberg, Ethan M., Curry, Michael P., Frenette, Catherine T., Regenstein, Fredric G., Schiff, Eugene R., Goodman, Zachary D., Robinson, James M., Chan, Jean L., Imperial, Joanne C., Reddy, K. Rajender

“…Despite achieving sustained virologic response (SVR) to hepatitis C virus (HCV) therapy, there remains a post liver transplantation population with advanced…”
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Which elements of improvement collaboratives are most effective? A cluster-randomized trial by Gustafson, David H., Quanbeck, Andrew R., Robinson, James M., Ford II, James H., Pulvermacher, Alice, French, Michael T., McConnell, K. John, Batalden, Paul B., Hoffman, Kim A., McCarty, Dennis

“…Aims Improvement collaboratives consisting of various components are used throughout health care to improve quality, but no study has identified which…”
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The efficacy and safety of a new enteric-coated formulation of fluoxetine given once weekly during the continuation treatment of major depressive disorder by SCHMIDT, Mark E, FAVA, Maurizio, ROBINSON, James M, JUDGE, Rajinder

“…A simple, once-weekly dosing regimen could be a convenient alternative for many patients during long-term treatment of depression. Such a strategy might also…”
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Increasing system-wide implementation of opioid prescribing guidelines in primary care: findings from a non-randomized stepped-wedge quality improvement project by Zgierska, Aleksandra E, Robinson, James M, Lennon, Robert P, Smith, Paul D, Nisbet, Kate, Ales, Mary W, Boss, Deanne, Tuan, Wen-Jan, Vidaver, Regina M, Hahn, David L

“…Clinician utilization of practice guidelines can reduce inappropriate opioid prescribing and harm in chronic non-cancer pain; yet, implementation of "opioid…”
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Impact of Fluoroquinolone Resistance Mutations on Gonococcal Fitness and In Vivo Selection for Compensatory Mutations by Kunz, Anjali N., Begum, Afrin A., Wu, Hong, D'Ambrozio, Jonathan A., Robinson, James M., Shafer, William M., Bash, Margaret C., Jerse, Ann E.

“…Background. Quinolone-resistant Neisseria gonorrhoeae (QRNG) arise from mutations in gyrA (intermediate resistance) or gyrA and parC (resistance). Here we…”
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Adaptation of the Grasha Riechman Student Learning Style Survey and Teaching Style Inventory to assess individual teaching and learning styles in a quality improvement collaborative by Ford, 2nd, James H, Robinson, James M, Wise, Meg E

“…NIATx200, a quality improvement collaborative, involved 201 substance abuse clinics. Each clinic was randomized to one of four implementation strategies: (a)…”
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Icequake locations and discrimination of source and path effects with small aperture arrays, Bering Glacier terminus, AK by Richardson, Joshua P., Waite, Gregory P., Pennington, Wayne D., Turpening, Roger M., Robinson, James M.

“…The complex source processes associated with both glacier calving and the breakup of icebergs, combined with commonly heterogeneous periglacial seismic…”
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Systems consultation: protocol for a novel implementation strategy designed to promote evidence-based practice in primary care by Quanbeck, Andrew, Brown, Randall T, E Zgierska, Aleksandra, A Johnson, Roberta, Robinson, James M, Jacobson, Nora

“…Adoption of evidence-based practices takes place at a glacial place in healthcare. This research will pilot test an innovative implementation strategy -…”
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To divide or manipulate the chorda tympani in stapedotomy by MAHENDRAN, Suresh, HOGG, Richard, ROBINSON, James M

“…The objective of this study is to determine the nature, duration and severity of chorda tympani symptoms in post-stapedotomy patients when the nerve has been…”
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