Search Results - "Robinson, I. C. A. F"

Growth Hormone-Releasing Hormone (GHRH) Neurons in GHRH-Enhanced Green Fluorescent Protein Transgenic Mice: A Ventral Hypothalamic Network by Balthasar, N, Mery, P.-F, Magoulas, C. B, Mathers, K. E, Martin, A, Mollard, P, Robinson, I. C. A. F

“…The hypothalamic GHRH neurons secrete pulses of GHRH to generate episodic GH secretion, but little is known about the mechanisms involved. We have made…”
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A Secreted Fluorescent Reporter Targeted to Pituitary Growth Hormone Cells in Transgenic Mice by Magoulas, C, McGuinness, L, Balthasar, N, Carmignac, D. F, Sesay, A. K, Mathers, K. E, Christian, H, Candeil, L, Bonnefont, X, Mollard, P, Robinson, I. C. A. F

“…In stable transfection experiments in the GH-producing GC cell line, a construct containing the entire signal peptide and the first 22 residues of human GH…”
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Sexually Dimorphic Distribution of sst2A Receptors on Growth Hormone-Releasing Hormone Neurones in Mice: Modulation by Gonadal Steroids by Bouyer, K., Faivre-Bauman, A., Robinson, I. C. A. F., Epelbaum, J., Loudes, C.

“…The ultradian pulsatile pattern of growth hormone (GH) secretion is markedly sexually dimorphic in rodents as in primates, but the neuroanatomical mechanisms…”
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Hypothalamic STAT Proteins: Regulation of Somatostatin Neurones by Growth Hormone Via STAT5b by Bennett, E., McGuinness, L., Gevers, E. F., Thomas, G. B., Robinson, I. C. A. F., Davey, H. W., Luckman, S. M.

“…Signal transducers and activators of transcription (STATs) are a family of transcription factors linked to class I cytokine receptors. In the present study, we…”
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Regulation of Galanin-Like Peptide Gene Expression By Pituitary Hormones and Their Downstream Targets by Cunnningham, M. J., Krasnow, S. M., Gevers, E. F., Chen, P., Thompson, C. K., Robinson, I. C. A. F., Smith, M. S., Clifton, D. K., Steiner, R. A.

“…Galanin‐like peptide (GALP) mRNA is expressed in neurones of the hypothalamic arcuate nucleus and within pituicytes in the neurohypophysis. Several…”
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Central effects of growth hormone-releasing hexapeptide (GHRP-6) on growth hormone release are inhibited by central somatostatin action by Fairhall, K M, Mynett, A, Robinson, I C

“…Growth hormone (GH) release is stimulated by a variety of synthetic secretagogues, of which growth hormone-releasing hexapeptide (GHRP-6) has been most…”
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Sexual dimorphism of hepatic 11 beta-hydroxysteroid dehydrogenase in the rat: the role of growth hormone patterns by Low, S C, Chapman, K E, Edwards, C R, Wells, T, Robinson, I C, Seckl, J R

“…11 beta-Hydroxysteroid dehydrogenase (11 beta-HSD) catalyses the reversible metabolism of corticosterone to inert 11-dehydrocorticosterone. At least two…”
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Growth hormone-deficient dwarfism in the rat: a new mutation by Charlton, H M, Clark, R G, Robinson, I C, Goff, A E, Cox, B S, Bugnon, C, Bloch, B A

“…Mutations in animals have provided insight into many aspects of normal and pathological human physiology. This paper reports the discovery and initial…”
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Growth responses in a mutant dwarf rat to human growth hormone and recombinant human insulin-like growth factor I by Skottner, A, Clark, R G, Fryklund, L, Robinson, I C

“…A new mutant GH-deficient dwarf rat has been used to study the effects of iv infusions of human GH (hGH) and recombinant human insulin-like growth factor I…”
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Peak and trough growth hormone (GH) concentrations influence growth and serum insulin like growth factor-1 (IGF-1) concentrations in short children by Achermann, J. C., Brook, C. G. D., Robinson, I. C. A. F., Matthews, D. R., Hindmarsh, P. C.

“…Summary OBJECTIVE Growth hormone (GH) is secreted in a pulsatile fashion promoting growth and a number of diverse metabolic actions. The precise components of…”
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Hypothalamic GH receptor gene expression in the rat: effects of altered GH status by Bennett, P A, Levy, A, Sophokleous, S, Robinson, I C, Lightman, S L

“…GH synthesis and release from the anterior pituitary is governed by the opposing actions of somatostatin (SS) and GH-releasing factor (GRF), derived from the…”
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Growth hormone secretory profiles in conscious female rats by Clark, R G, Carlsson, L M, Robinson, I C

“…An automatic method for repetitive microsampling of blood from conscious animals was used to obtain detailed GH secretory profiles from normal female rats,…”
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Intravenous growth hormone: growth responses to patterned infusions in hypophysectomized rats by Clark, R G, Jansson, J O, Isaksson, O, Robinson, I C

“…Young hypophysectomized rats were maintained with chronic indwelling i.v. cannulae attached via swivels to a multichannel pumping system programmed to deliver…”
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The rebound release of growth hormone (GH) following somatostatin infusion in rats involves hypothalamic GH-releasing factor release by Clark, R G, Carlsson, L M, Rafferty, B, Robinson, I C

“…We have studied the rebound secretion of GH following short-term somatostatin (SS) infusions in conscious rats, using an automatic sampling system for…”
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High plasma insulin-like growth factor-II and low lipid content in transgenic mice: measurements of lipid metabolism by Da Costa, T H, Williamson, D H, Ward, A, Bates, P, Fisher, R, Richardson, L, Hill, D J, Robinson, I C, Graham, C F

“…Transgenic mice were made by introducing extra copies of the mouse insulin-like growth factor-II (IGF-II) gene driven by the bovine keratin 10 promoter (BKVI)…”
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Growth hormone (GH)-binding protein in normal and GH-deficient dwarf rats by Carmignac, D F, Wells, T, Carlsson, L M, Clark, R G, Robinson, I C

“…There are GH-binding proteins (GHBPs) present in the blood of many species, and these correspond to the extracellular GH-binding domain of the GH receptor. In…”
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Sex difference in growth hormone feedback in the rat by Carlsson, L M, Clark, R G, Robinson, I C

“…Growth hormone inhibits its own secretion in animals and man but the mechanism for this inhibition is unclear: both stimulation of somatostatin release and…”
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Automated repetitive microsampling of blood: growth hormone profiles in conscious male rats by Clark, R G, Chambers, G, Lewin, J, Robinson, I C

“…A system is described for the automatic collection of small samples of blood from conscious rats. Rats bearing chronic indwelling i.v. catheters were connected…”
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Effect of gonadectomy on growth and GH responsiveness in dwarf rats by Gevers, E F, Wit, J M, Robinson, I C

“…Normal rats are sexually dimorphic in their growth and GH secretion. Gonadectomy (Gnx) changes the GH secretory pattern and this could explain differential…”
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Recombinant human insulin-like growth factor: testing the somatomedin hypothesis in hypophysectomized rats by Skottner, A, Clark, R G, Robinson, I C, Fryklund, L

“…The in-vivo biological activity of recombinant methionyl insulin-like growth factor I (met-IGF-I) was demonstrated in hypophysectomized rats by following blood…”
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