Search Results - "Robinson, G W"
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The Role of Inherited TPMT and COMT Genetic Variation in Cisplatin-Induced Ototoxicity in Children With Cancer
Published in Clinical pharmacology and therapeutics (01-08-2013)“…Ototoxicity is a debilitating side effect of platinating agents with substantial interpatient variability. We sought to evaluate the association of thiopurine…”
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Think globally, act locally: the making of a mouse mammary gland
Published in Genes & development (15-02-1998)“…On a phylogenetic scale of organ development the mammary gland is a recent acquisition. It was introduced 200 million years ago with the appearance of mammals…”
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Stat5a is mandatory for adult mammary gland development and lactogenesis
Published in Genes & development (15-01-1997)“…Prolactin (PRL) induces mammary gland development (defined as mammopoiesis) and lactogenesis. Binding of PRL to its receptor leads to the phosphorylation and…”
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4
Loss of cyclin D1 in concert with deregulated estrogen receptor a expression induces DNA damage response activation and interrupts mammary gland morphogenesis
Published in Oncogene (15-05-2008)“…We have previously shown that increased and deregulated estrogen receptor alpha expression in the mammary gland leads to the development of proliferative…”
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Regulation of mammary gland development by tissue interaction
Published in Journal of mammary gland biology and neoplasia (01-01-1999)“…Development of the mammary glands is initiated in the embryo but the major part of their development occurs in the adult. While development in puberty and…”
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Loss of cyclin D1 in concert with deregulated estrogen receptor α expression induces DNA damage response activation and interrupts mammary gland morphogenesis
Published in Oncogene (15-05-2008)“…We have previously shown that increased and deregulated estrogen receptor α expression in the mammary gland leads to the development of proliferative disease…”
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7
A multifaceted health‐service intervention in remote Aboriginal communities: 3‐year follow‐up of the impact on diabetes care
Published in Medical journal of Australia (16-08-2004)“…Objective: To examine the trends in processes of diabetes care and in participant outcomes after an intervention in two remote regions of Australia. Design:…”
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Signaling Pathways in Mammary Gland Development
Published in Developmental Cell (01-10-2001)“…Unlike most other organs, development of the mammary gland occurs predominantly after birth, under the control of steroid and peptide hormones. Once the gland…”
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Origin of Temperature and Pressure Effects on the Radial Distribution Function of Water
Published in Physical review letters (20-09-1999)Get full text
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Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation
Published in Molecular and Cellular Biology (01-05-1993)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Molecular cloning and characterization of the yeast gene for squalene synthetase
Published in Proceedings of the National Academy of Sciences - PNAS (15-07-1991)“…Squalene synthetase (farnesyl-diphosphate: farnesyl-diphosphate farnesyltransferase, EC 2.5.1.21) is a critical branch point enzyme of isoprenoid biosynthesis…”
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Cloning and Expression of Stat5 and an Additional Homologue (Stat5b) Involved in Prolactin Signal Transduction in Mouse Mammary Tissue
Published in Proceedings of the National Academy of Sciences - PNAS (12-09-1995)“…Prolactin (PRL) induces transcriptional activation of milk protein genes, such as the whey acidic protein (WAP), β-casein, and β-lactoglobulin genes, through a…”
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13
Epithelial Defect in Prostates of Stat5a-Null Mice
Published in Laboratory investigation (01-07-2000)“…The transcription factor Stat5a critically mediates prolactin (PRL)-induced mammary gland development and lactogenesis. PRL also stimulates growth and…”
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Chromosomal insertions and deletions in Streptococcus mutans
Published in Caries research (01-03-2003)“…Many isolates of Streptococcus mutans lack the ability to ferment melibiose and other sugars. We previously reported that this was commonly due to a…”
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Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland
Published in Development (Cambridge) (01-09-2002)“…PTEN tumor suppressor is frequently mutated in human cancers, including breast cancers. Female patients with inherited PTEN mutations suffer from virginal…”
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Signal Transducer and Activator of Transcription (Stat) 5 Controls the Proliferation and Differentiation of Mammary Alveolar Epithelium
Published in The Journal of cell biology (12-11-2001)“…Functional development of mammary epithelium during pregnancy depends on prolactin signaling. However, the underlying molecular and cellular events are not…”
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Genomic architecture and transcriptional activation of the mouse and human tumor susceptibility gene TSG101 : Common types of shorter transcripts are true alternative splice variants
Published in Oncogene (26-11-1998)“…The functional inactivation of the tumor susceptibility gene tsg101 in mouse NIH3T3 cells leads to cell transformation and the formation of metastatic tumors…”
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Cloning and characterization of ERG8, an essential gene of Saccharomyces cerevisiae that encodes phosphomevalonate kinase
Published in Molecular and Cellular Biology (01-02-1991)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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19
Yeast squalene synthase: expression, purification, and characterization of soluble recombinant enzyme
Published in Archives of biochemistry and biophysics (01-07-1993)“…Squalene synthase is the first pathway-specific enzyme in the cholesterol biosynthetic pathway. The gene (ERG9) encoding squalene synthase in Saccharomyces…”
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Protein denaturation described by a two-state structural model of liquid water
Published in Cellular and molecular biology (Noisy-le-Grand, France) (01-07-2001)“…Our laboratory has been involved in expounding an outer neighbor molecular-level structural theory for liquid water in the supercooled and ordinary…”
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