Search Results - "Robinson, Elektra K"

The how and why of lncRNA function: An innate immune perspective by Robinson, Elektra K., Covarrubias, Sergio, Carpenter, Susan

“…Next-generation sequencing has provided a more complete picture of the composition of the human transcriptome indicating that much of the “blueprint” is a…”
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Malonylation of GAPDH is an inflammatory signal in macrophages by Galván-Peña, Silvia, Carroll, Richard G., Newman, Carla, Hinchy, Elizabeth C., Palsson-McDermott, Eva, Robinson, Elektra K., Covarrubias, Sergio, Nadin, Alan, James, Andrew M., Haneklaus, Moritz, Carpenter, Susan, Kelly, Vincent P., Murphy, Michael P., Modis, Louise K., O’Neill, Luke A.

“…Macrophages undergo metabolic changes during activation that are coupled to functional responses. The gram negative bacterial product lipopolysaccharide (LPS)…”
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Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2 by Elling, Roland, Robinson, Elektra K., Shapleigh, Barbara, Liapis, Stephen C., Covarrubias, Sergio, Katzman, Sol, Groff, Abigail F., Jiang, Zhaozhao, Agarwal, Shiuli, Motwani, Mona, Chan, Jennie, Sharma, Shruti, Hennessy, Elizabeth J., FitzGerald, Garret A., McManus, Michael T., Rinn, John L., Fitzgerald, Katherine A., Carpenter, Susan

“…An inducible gene expression program is a hallmark of the host inflammatory response. Recently, long intergenic non-coding RNAs (lincRNAs) have been shown to…”
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Transcriptomic analysis reveals distinct effects of cigarette smoke on murine airspace and bone-marrow derived macrophages by Faherty, Lynne, Zhang, William Z, Salih, Mays M, Robinson, Elektra K, Perez, Elizabeth, Kim, Kihwan, Carpenter, Susan, Cloonan, Suzanne M

“…Chronic obstructive pulmonary disease (COPD) is an inflammatory airway disease characterized by emphysema and chronic bronchitis and a leading cause of…”
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Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of Aim2 by Robinson, Elektra K, Jagannatha, Pratibha, Covarrubias, Sergio, Cattle, Matthew, Smaliy, Valeriya, Safavi, Rojin, Shapleigh, Barbara, Abu-Shumays, Robin, Jain, Miten, Cloonan, Suzanne M, Akeson, Mark, Brooks, Angela N, Carpenter, Susan

“…Determining the layers of gene regulation within the innate immune response is critical to our understanding of the cellular responses to infection and…”
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CRISPR/Cas-based screening of long non-coding RNAs (lncRNAs) in macrophages with an NF-κB reporter by Covarrubias, Sergio, Robinson, Elektra K., Shapleigh, Barbara, Vollmers, Apple, Katzman, Sol, Hanley, Nicole, Fong, Nicholas, McManus, Michael T., Carpenter, Susan

“…The innate immune system protects against infections by initiating an inducible inflammatory response. NF-κB is one of the critical transcription factors…”
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Helicobacter pylori Chronic-Stage Inflammation Undergoes Fluctuations That Are Altered in tlpA Mutants by Johnson, Kevin S, Yang, Christina, Carter, J Elliot, Worthington, Atesh K, Robinson, Elektra K, Lopez-Magaña, Raymond, Salgado, Frida, Arnold, Isabelle, Ottemann, Karen M

“…Helicobacter pylori colonizes half of the world's population and is responsible for a significant disease burden by causing gastritis, peptic ulcers, and…”
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High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways by Covarrubias, Sergio, Vollmers, Apple Cortez, Capili, Allyson, Boettcher, Michael, Shulkin, Aaron, Correa, Michele Ramos, Halasz, Haley, Robinson, Elektra K., O’Briain, Laura, Vollmers, Christopher, Blau, James, Katzman, Sol, McManus, Michael T., Carpenter, Susan

“…Macrophages are critical effector cells of the immune system, and understanding genes involved in their viability and function is essential for gaining…”
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