Search Results - "Robinson, D."

A scaling normalization method for differential expression analysis of RNA-seq data by Robinson, Mark D, Oshlack, Alicia

“…The fine detail provided by sequencing-based transcriptome surveys suggests that RNA-seq is likely to become the platform of choice for interrogating steady…”
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Regulatory T cells and asthma by Robinson, D. S.

“…Airway inflammation in asthma is characterized by activation of T helper type‐2 (Th2) T cells, IgE production and eosinophilia. In many cases, this process is…”
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Robustly detecting differential expression in RNA sequencing data using observation weights by Zhou, Xiaobei, Lindsay, Helen, Robinson, Mark D

“…A popular approach for comparing gene expression levels between (replicated) conditions of RNA sequencing data relies on counting reads that map to features of…”
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Comparison of clustering methods for high‐dimensional single‐cell flow and mass cytometry data by Weber, Lukas M., Robinson, Mark D.

“…Recent technological developments in high‐dimensional flow cytometry and mass cytometry (CyTOF) have made it possible to detect expression levels of dozens of…”
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A Review of Merged High-Resolution Satellite Precipitation Product Accuracy during the Tropical Rainfall Measuring Mission (TRMM) Era by Maggioni, Viviana, Meyers, Patrick C., Robinson, Monique D.

“…A great deal of expertise in satellite precipitation estimation has been developed during the Tropical Rainfall Measuring Mission (TRMM) era (1998–2015). The…”
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Fecal microbiota transplant from a rational stool donor improves hepatic encephalopathy: A randomized clinical trial by Bajaj, Jasmohan S., Kassam, Zain, Fagan, Andrew, Gavis, Edith A., Liu, Eric, Cox, I. Jane, Kheradman, Raffi, Heuman, Douglas, Wang, Jessica, Gurry, Thomas, Williams, Roger, Sikaroodi, Masoumeh, Fuchs, Michael, Alm, Eric, John, Binu, Thacker, Leroy R., Riva, Antonio, Smith, Mark, Taylor‐Robinson, Simon D., Gillevet, Patrick M

“…Recurrent hepatic encephalopathy (HE) is a leading cause of readmission despite standard of care (SOC) associated with microbial dysbiosis. Fecal microbiota…”
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edgeR: a Bioconductor package for differential expression analysis of digital gene expression data by Robinson, Mark D., McCarthy, Davis J., Smyth, Gordon K.

“…It is expected that emerging digital gene expression (DGE) technologies will overtake microarray technologies in the near future for many functional genomics…”
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Revisiting Type 2‐high and Type 2‐low airway inflammation in asthma: current knowledge and therapeutic implications by Robinson, D., Humbert, M., Buhl, R., Cruz, A. A., Inoue, H., Korom, S., Hanania, N. A., Nair, P.

“…Summary Asthma is a complex respiratory disorder characterized by marked heterogeneity in individual patient disease triggers and response to therapy. Several…”
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The diversity and evolution of ecological and environmental citizen science by Pocock, Michael J O, Tweddle, John C, Savage, Joanna, Robinson, Lucy D, Roy, Helen E

“…Citizen science-the involvement of volunteers in data collection, analysis and interpretation-simultaneously supports research and public engagement with…”
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Risk factors for intrahepatic and extrahepatic cholangiocarcinoma: A systematic review and meta-analysis by Clements, Oliver, Eliahoo, Joseph, Kim, Jin Un, Taylor-Robinson, Simon D., Khan, Shahid A.

“…[Display omitted] •Choledochal cysts were found to be most strongly associated with both iCCA and eCCA.•Cirrhosis was a significant CCA risk, with a stronger…”
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High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy by Krieg, Carsten, Nowicka, Malgorzata, Guglietta, Silvia, Schindler, Sabrina, Hartmann, Felix J, Weber, Lukas M, Dummer, Reinhard, Robinson, Mark D, Levesque, Mitchell P, Becher, Burkhard

“…Among many populations of blood cells, high dimensional analysis using mass cytometry reveals classical monocyte frequency as strong predictors of response to…”
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Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences by Soneson, Charlotte, Love, Michael I, Robinson, Mark D

“…High-throughput sequencing of cDNA (RNA-seq) is used extensively to characterize the transcriptome of cells. Many transcriptomic studies aim at comparing…”
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N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer by Dardenne, Etienne, Beltran, Himisha, Benelli, Matteo, Gayvert, Kaitlyn, Berger, Adeline, Puca, Loredana, Cyrta, Joanna, Sboner, Andrea, Noorzad, Zohal, MacDonald, Theresa, Cheung, Cynthia, Yuen, Ka Shing, Gao, Dong, Chen, Yu, Eilers, Martin, Mosquera, Juan-Miguel, Robinson, Brian D., Elemento, Olivier, Rubin, Mark A., Demichelis, Francesca, Rickman, David S.

“…The transition from castration-resistant prostate adenocarcinoma (CRPC) to neuroendocrine prostate cancer (NEPC) has emerged as an important mechanism of…”
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A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes by Soneson, Charlotte, Yao, Yao, Bratus-Neuenschwander, Anna, Patrignani, Andrea, Robinson, Mark D., Hussain, Shobbir

“…A platform for highly parallel direct sequencing of native RNA strands was recently described by Oxford Nanopore Technologies, but despite initial efforts it…”
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pipeComp, a general framework for the evaluation of computational pipelines, reveals performant single cell RNA-seq preprocessing tools by Germain, Pierre-Luc, Sonrel, Anthony, Robinson, Mark D

“…We present pipeComp ( https://github.com/plger/pipeComp ), a flexible R framework for pipeline comparison handling interactions between analysis steps and…”
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Treatment of a metabolic liver disease by in vivo genome base editing in adult mice by Villiger, Lukas, Grisch-Chan, Hiu Man, Lindsay, Helen, Ringnalda, Femke, Pogliano, Chiara B., Allegri, Gabriella, Fingerhut, Ralph, Häberle, Johannes, Matos, Joao, Robinson, Mark D., Thöny, Beat, Schwank, Gerald

“…CRISPR–Cas-based genome editing holds great promise for targeting genetic disorders, including inborn errors of hepatocyte metabolism. Precise correction of…”
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muscat detects subpopulation-specific state transitions from multi-sample multi-condition single-cell transcriptomics data by Crowell, Helena L., Soneson, Charlotte, Germain, Pierre-Luc, Calini, Daniela, Collin, Ludovic, Raposo, Catarina, Malhotra, Dheeraj, Robinson, Mark D.

“…Single-cell RNA sequencing (scRNA-seq) has become an empowering technology to profile the transcriptomes of individual cells on a large scale. Early analyses…”
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Northern Hemisphere spring snow cover variability and change over 1922–2010 including an assessment of uncertainty by Brown, R. D., Robinson, D. A.

“…An update is provided of Northern Hemisphere (NH) spring (March, April) snow cover extent (SCE) over the 1922–2010 period incorporating the new climate data…”
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A long-term Northern Hemisphere snow cover extent data record for climate studies and monitoring by Estilow, T. W, Young, A. H, Robinson, D. A

“…This paper describes the long-term, satellite-based visible snow cover extent National Oceanic and Atmospheric Administration (NOAA) climate data record (CDR)…”
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Unified Method for Estimating the Ultimate Bearing Capacity of Shallow Foundations in Variably Saturated Soils under Steady Flow by Vahedifard, Farshid, Robinson, Joe D

“…AbstractThis study presents a unified method for estimating the ultimate bearing capacity of shallow foundations resting on variably saturated soils under a…”
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