Search Results - "Robinet, Pauline"
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A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK cells
Published in The Journal of immunology (1950) (01-06-2014)“…Aspergillus fumigatus is an opportunistic human fungal pathogen that sheds galactosaminogalactan (GG) into the environment. Polymorphonuclear neutrophils…”
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Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression
Published in Frontiers in immunology (18-04-2019)“…Oral infection (30 cysts of 76K strain) induces acute lethal ileitis in sensitive C57BL/6 (B6) mice with increased expression of IL-33 and its receptor ST2 in…”
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Corrigendum: Blockade of IL-33R/ST2 Signaling Attenuates Toxoplasma gondii Ileitis Depending on IL-22 Expression
Published in Frontiers in immunology (28-10-2020)Get full text
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Apoptotic activity of a nuclear form of mitogaligin, a cell death protein
Published in Biochemical and biophysical research communications (23-01-2009)“…Galig, an internal gene to the galectin-3 gene, encodes two proteins and induces cell death in human cells. Mitogaligin, one of these proteins, contains a…”
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Biosynthesis of cell wall mannan in the conidium and the mycelium of Aspergillus fumigatus
Published in Cellular microbiology (01-12-2016)“…The galactomannan is a major cell wall molecule of Aspergillus fumigatus. This molecule is composed of a linear mannan with a repeating unit composed of four…”
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The protein phosphatase PhzA of A. fumigatus is involved in oxidative stress tolerance and fungal virulence
Published in Fungal genetics and biology (01-05-2014)“…•Protein phosphatases Z are unique to the fungal kingdom.•In A. fumigatus, PhzA is involved in the control of oxidative stress.•The ΔphzA mutant showed an…”
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First Report of CD4 Lymphopenia and Defective Neutrophil Functions in a Patient with Amebiasis Associated with CMV Reactivation and Severe Bacterial and Fungal Infections
Published in Frontiers in microbiology (13-02-2017)“…We report the case of a patient with acute necrotizing colitis due to invasive amebiasis associated with CD4 lymphopenia and impaired neutrophil responses. The…”
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Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells
Published in Molecular immunology (01-11-2013)“…•GALIG is a cell death-related gene nested within the human galectin-3 locus.•GALIG pro-apoptotic function is counteracted by the anti-apoptotic Mcl-1.•During…”
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The mitogaligin protein is addressed to the nucleus via a non-classical localization signal
Published in Biochemical and biophysical research communications (29-01-2010)“…Mitogaligin, a protein encoded by galig, an internal cytotoxic gene of the galectin-3 locus, is mostly a mitochondrial protein. Mitochondrial targeting is due…”
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Blockade of IL-1R signaling diminishes Paneth cell depletion and Toxoplasma gondii induced ileitis in mice
Published in American journal of clinical and experimental immunology (01-01-2013)“…Interleukin 1 is a critical inflammatory mediator and involved in host defense to several pathogens. Oral T. gondii infection causes lethal ileitis in C57BL/6…”
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