Search Results - "Robertson, Louise J"
-
1
Functional screening of GATOR1 complex variants reveals a role for mTORC1 deregulation in FCD and focal epilepsy
Published in Neurobiology of disease (01-02-2020)“…Mutations in the GAP activity toward RAGs 1 (GATOR1) complex genes (DEPDC5, NPRL2 and NPRL3) have been associated with focal epilepsy and focal cortical…”
Get full text
Journal Article -
2
Investigating the potential of X chromosome shredding for mouse genetic biocontrol
Published in Scientific reports (12-06-2024)“…CRISPR-Cas9 technology has facilitated development of strategies that can potentially provide more humane and effective methods to control invasive vertebrate…”
Get full text
Journal Article -
3
User experience analysis of AbC-19 Rapid Test via lateral flow immunoassays for self-administrated SARS-CoV-2 antibody testing
Published in Scientific reports (07-07-2021)“…Lateral flow immunoassays are low cost, rapid and highly efficacious point-of-care devices, which have been used for SARS-CoV-2 antibody testing by…”
Get full text
Journal Article -
4
User experience of home-based AbC-19 SARS-CoV-2 antibody rapid lateral flow immunoassay test
Published in Scientific reports (21-01-2022)“…The urgent need to scale up testing capacity during the COVID-19 pandemic has prompted the rapid development of point-of-care diagnostic tools such as lateral…”
Get full text
Journal Article -
5
Evaluation of the IgG antibody response to SARS CoV-2 infection and performance of a lateral flow immunoassay: cross-sectional and longitudinal analysis over 11 months
Published in BMJ open (29-06-2021)“…ObjectiveTo evaluate the dynamics and longevity of the humoral immune response to SARS-CoV-2 infection and assess the performance of professional use of the…”
Get full text
Journal Article -
6
IgG antibody production and persistence to 6 months following SARS-CoV-2 vaccination: A Northern Ireland observational study
Published in Vaccine (20-04-2022)“…This study evaluates spike protein IgG antibody response following Oxford-AstraZeneca COVID-19 vaccination using the AbC-19™ lateral flow device. Plasma…”
Get full text
Journal Article -
7
Mutation-Independent Allele-Specific Editing by CRISPR-Cas9, a Novel Approach to Treat Autosomal Dominant Disease
Published in Molecular therapy (05-08-2020)“…CRISPR-Cas9 provides a tool to treat autosomal dominant disease by non-homologous end joining (NHEJ) gene disruption of the mutant allele. In order to…”
Get full text
Journal Article