Search Results - "Robertson, Kelly L."
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1
Nobiletin affects circadian rhythms and oncogenic characteristics in a cell-dependent manner
Published in PloS one (24-07-2020)“…The natural product nobiletin is a small molecule, widely studied with regard to its therapeutic effects, including in cancer cell lines and tumors. Recently,…”
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2
Adaptation of the black yeast Wangiella dermatitidis to ionizing radiation: molecular and cellular mechanisms
Published in PloS one (06-11-2012)“…Observations of enhanced growth of melanized fungi under low-dose ionizing radiation in the laboratory and in the damaged Chernobyl nuclear reactor suggest…”
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3
Viral nanoparticle-encapsidated enzyme and restructured DNA for cell delivery and gene expression
Published in Proceedings of the National Academy of Sciences - PNAS (16-09-2014)“…Packaging specific exogenous active proteins and DNAs together within a single viral-nanocontainer is challenging. The bacteriophage T4 capsid (100 × 70 nm) is…”
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4
Function and regulation of Vibrio campbellii proteorhodopsin: acquired phototrophy in a classical organoheterotroph
Published in PloS one (07-06-2012)“…Proteorhodopsins (PRs) are retinal-binding photoproteins that mediate light-driven proton translocation across prokaryotic cell membranes. Despite their…”
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5
Oncogenic and Circadian Effects of Small Molecules Directly and Indirectly Targeting the Core Circadian Clock
Published in Integrative cancer therapies (2020)“…Circadian rhythms are essential for controlling the cell cycle, cellular proliferation, and apoptosis, and hence are tightly linked to cell fate. Several…”
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6
LNA flow–FISH: A flow cytometry–fluorescence in situ hybridization method to detect messenger RNA using locked nucleic acid probes
Published in Analytical biochemistry (15-07-2009)“…We present a novel method using flow cytometry–fluorescence in situ hybridization (flow–FISH) to detect specific messenger RNA (mRNA) in suspended cells using…”
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7
Locked Nucleic Acid and Flow Cytometry-Fluorescence In Situ Hybridization for the Detection of Bacterial Small Noncoding RNAs
Published in Applied and Environmental Microbiology (01-01-2012)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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8
Engineered T4 Viral Nanoparticles for Cellular Imaging and Flow Cytometry
Published in Bioconjugate chemistry (20-04-2011)“…Viruses are of particular interest as scaffolds for biotechnology applications given their wide range of shapes and sizes and the possibility to modify them…”
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9
Identification of non-coding RNAs in environmental vibrios
Published in Microbiology (Society for General Microbiology) (01-08-2010)“…The discovery of non-coding RNA (ncRNA) has been mainly limited to laboratory model systems and human pathogenic bacteria. In this study, we begin to explore…”
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10
Synthesis of New Fluorogenic Cyanine Dyes and Incorporation into RNA Fluoromodules
Published in Organic letters (17-04-2008)“…A new fluorogenic cyanine dye was synthesized and found to have low fluorescence quantum yield in fluid solution and in the presence of double-stranded DNA but…”
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11
Probing the Donor and Acceptor Substrate Specificity of the γ-Glutamyl Transpeptidase
Published in Biochemistry (Easton) (14-02-2012)“…γ-Glutamyl transpeptidase (GGT) is a two-substrate enzyme that plays a central role in glutathione metabolism and is a potential target for drug design. GGT…”
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12
Blue fluorescent dye-protein complexes based on fluorogenic cyanine dyes and single chain antibody fragments
Published in Organic & biomolecular chemistry (21-02-2011)“…Fluoromodules are complexes formed upon the noncovalent binding of a fluorogenic dye to its cognate biomolecular partner, which significantly enhances the…”
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13
A novel Vibrio beta-glucosidase (LamN) that hydrolyzes the algal storage polysaccharide laminarin
Published in FEMS microbiology ecology (01-08-2015)“…The metabolic versatility, tractability and rapid growth potential of the Vibrio spp. have made them increasingly attractive systems for investigating carbon…”
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14
Monitoring viral RNA in infected cells with LNA flow-FISH
Published in RNA (Cambridge) (01-08-2010)“…We previously showed the feasibility of using locked nucleic acid (LNA) for flow cytometric-fluorescence in situ hybridization (LNA flow-FISH) detection of a…”
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15
3‑Substituted Indole Inhibitors Against Francisella tularensis FabI Identified by Structure-Based Virtual Screening
Published in Journal of medicinal chemistry (11-07-2013)“…In this study, we describe novel inhibitors against Francisella tularensis SchuS4 FabI identified from structure-based in silico screening with integrated…”
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16
hard microflow cytometer using groove-generated sheath flow for multiplexed bead and cell assays
Published in Analytical & bioanalytical chemistry (Print) (01-11-2010)“…With a view toward developing a rugged microflow cytometer, a sheath flow system was micromachined in hard plastic (polymethylmethacrylate) for analysis of…”
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Journal Article Conference Proceeding -
17
Engineered viral nanoparticles for flow cytometry and fluorescence microscopy applications
Published in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology (01-09-2012)“…Viral nanoparticles (VNPs) are attractive platforms for use in the biotechnology and biomedical fields because of their biological nature. A wide variety of…”
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18
Locked nucleic acid flow cytometry-fluorescence in situ hybridization (LNA flow-FISH): a method for bacterial small RNA detection
Published in Journal of visualized experiments (10-01-2012)“…Fluorescence in situ hybridization (FISH) is a powerful technique that is used to detect and localize specific nucleic acid sequences in the cellular…”
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19
Fluorescent PNA Probes as Hybridization Labels for Biological RNA
Published in Biochemistry (Easton) (16-05-2006)“…Fluorescent labeling of biological RNA is complicated by the narrow range of nucleoside triphosphates that can be used for biological synthesis (i.e.,…”
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20
Engineered bacteriophage T4 nanoparticles for cellular imaging
Published in Methods in molecular biology (Clifton, N.J.) (2014)“…Tailless T4 nanoparticles (NPs) have large surface areas consisting of more than 10(5) diverse surface reactive groups and offer great flexibility in chemical…”
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