Search Results - "Robertson, Darrell A"

Early Growth Response Genes Regulate B Cell Development, Proliferation, and Immune Response by Gururajan, Murali, Simmons, Alan, Dasu, Trivikram, Spear, Brett T, Calulot, Christopher, Robertson, Darrell A, Wiest, David L, Monroe, John G, Bondada, Subbarao

“…Egr-1 (early growth response gene-1) is an immediate early gene encoding a zinc finger motif-containing transcription factor. Upon cross-linking of BCR, mature…”
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Anomalous constitutive Src kinase activity promotes B lymphoma survival and growth by Ke, Jiyuan, Chelvarajan, R Lakshman, Sindhava, Vishal, Robertson, Darrell A, Lekakis, Lazaros, Jennings, C Darrell, Bondada, Subbarao

“…Previously we have shown that B cell receptor (BCR) expression and B cell receptor signaling pathways are important for the basal growth of B lymphoma cells…”
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Spleen tyrosine kinase (Syk), a novel target of curcumin, is required for B lymphoma growth by Gururajan, Murali, Dasu, Trivikram, Shahidain, Seif, Jennings, C Darrell, Robertson, Darrell A, Rangnekar, Vivek M, Bondada, Subbarao

“…Curcumin (diferuloylmethane), a component of dietary spice turmeric (Curcuma longa), has been shown in recent studies to have therapeutic potential in the…”
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Accessory cell defect in unresponsiveness of neonates and aged to polysaccharide vaccines by Bondada, Subbarao, Wu, Hsin-Jung, Robertson, Darrell A, Chelvarajan, Ralph L

“…T independent antigens elicit antibody responses in the absence of carrier specific T helper cells but require signals from accessory cells (macrophages and…”
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Defective CD19-dependent signaling in B-1a and B-1b B lymphocyte subpopulations by Sen, Goutam, Wu, Hsin-Jung, Bikah, Gabriel, Venkataraman, Chandrasekar, Robertson, Darrell A, Snow, E.Charles, Bondada, Subbarao

“…Peritoneal and pleural cavities in mice and humans contain a unique population of B-lymphocytes called B-1 cells that are defective in B cell antigen receptor…”
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Assays for B lymphocyte function by Bondada, Subbarao, Robertson, Darrell A

“…This unit describes the antigenic stimulation of in vitro antibody production by B cells and the subsequent measurement of secreted antibodies. The first basic…”
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CpG oligodeoxynucleotides overcome the unresponsiveness of neonatal B cells to stimulation with the thymus‐independent stimuli anti‐IgM and TNP‐Ficoll by Chelvarajan, Ralph L., Raithatha, Roheen, Venkataraman, Chandrasekar, Kaul, Rajat, Han, Seong‐Su, Robertson, Darrell A., Bondada, Subbarao

“…Neonates are very vulnerable to pathogenic encapsulated bacteria due to their inability to mount an antibody response to capsular polysaccharides, which are…”
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Curcumin Causes the Growth Arrest and Apoptosis of B Cell Lymphoma by Downregulation of egr-1, C-myc, Bcl-XL, NF-κB, and p53 by Han, Seong-Su, Chung, Seung-Tae, Robertson, Darrell A., Ranjan, Dinesh, Bondada, Subbarao

“…It has been well known that curcumin is a powerful inhibitor of proliferation of several tumor cells. However, the molecular basis of the anti-proliferative…”
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