Search Results - "Roberts, Samantha A."

Reducing the toxicity of cancer therapy: recognizing needs, taking action by Cleeland, Charles S., Allen, Jeff D., Roberts, Samantha A., Brell, Joanna M., Giralt, Sergio A., Khakoo, Aarif Y., Kirch, Rebecca A., Kwitkowski, Virginia E., Liao, Zhongxing, Skillings, Jamey

“…A multidisciplinary colloquium—Developing Strategies for Reducing Cancer Treatment-Related Toxicities and Symptoms—was held to identify the challenges that…”
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The Value of Addressing Patient Preferences by Allen, Jeff D., PhD, Stewart, Mark D., PhD, Roberts, Samantha A., PhD, Sigal, Ellen V., PhD

“…Abstract Recent scientific progress is, in some cases, leading to transformative new medicines for diseases that previously had marginal or even no treatment…”
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A fresh perspective on comparing the FDA and the CHMP/EMA: approval of antineoplastic tyrosine kinase inhibitors by Shah, Rashmi R., Roberts, Samantha A., Shah, Devron R.

“…We compared and determined the reasons for any differences in the review and approval times of tyrosine kinase inhibitors (TKIs) by the US Food and Drug…”
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Intraoperative Embolization during Inferior Vena Cava Tumor Thrombectomy for Renal Cell Carcinoma by Roberts, Samantha A, Satija, Divyaam, Gold, Henry, Makary, Mina S, Wang, Jing G, Singer, Eric A, Posid, Tasha, Mokadam, Nahush A, Dason, Shawn

“…Intraoperative tumor thrombus embolization is a potentially lethal complication during inferior vena cava (IVC) thrombectomy for renal cell carcinoma (RCC)…”
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Use of Multiple Endpoints and Approval Paths Depicts a Decade of FDA Oncology Drug Approvals by SHEA, Michael B, ROBERTS, Samantha A, WALRATH, Jessica C, ALLEN, Jeff D, SIGAL, Ellen V

“…This study explores the historic use of different endpoints to support regular and accelerated approval of cancer drugs between 2002 and 2012. In the past 10…”
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Developing Standards for Breakthrough Therapy Designation in Oncology by HORNING, Sandra J, HABER, Daniel A, SELIG, Wendy K. D, IVY, S. Percy, ROBERTS, Samantha A, ALLEN, Jeff D, SIGAL, Ellen V, SAWYERS, Charles L

“…In July 2012, Congress passed the Food and Drug Administration Safety and Innovation Act (FDASIA). The Advancing Breakthrough Therapies for Patients Act was…”
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Adoption consideration and concerns among young adult female cancer survivors by Gorman, Jessica R., Whitcomb, Brian W., Standridge, Daniel, Malcarne, Vanessa L., Romero, Sally A.D., Roberts, Samantha A., Su, H. Irene

“…Purpose We compared adoption consideration between female young adult cancer survivors and women of the same age in the general US population, hypothesizing…”
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Occludin, caveolin‐1, and Alix form a multi‐protein complex and regulate HIV‐1 infection of brain pericytes by Torices, Silvia, Roberts, Samantha A., Park, Minseon, Malhotra, Arun, Toborek, Michal

“…HIV‐1 enters the brain by altering properties of the blood‐brain barrier (BBB). Recent evidence indicates that among cells of the BBB, pericytes are prone to…”
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Unraveling the Regulatory Network in Streptococcus pyogenes: the Global Response Regulator CovR Represses rivR Directly by ROBERTS, Samantha A, CHURCHWARD, Gordon G, SCOTT, June R

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Achieving the Goals of Effective, Safe, and Individualized Cancer Care by ROBERTS, Samantha A, KARNES, Erin K, ALLEN, Jeffrey D, BENNER, Joshua S, SIGAL, Ellen V, MCCLELLAN, Mark

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TrxR, a New CovR-Repressed Response Regulator That Activates the Mga Virulence Regulon in Group A Streptococcus by Leday, Temekka V, Gold, Kathryn M, Kinkel, Traci L, Roberts, Samantha A, Scott, June R, McIver, Kevin S

“…Coordinate regulation of virulence factors by the group A streptococcus (GAS) Streptococcus pyogenes is important in this pathogen's ability to cause disease…”
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Despite criticism of the FDA review process, new cancer drugs reach patients sooner in the United States than in Europe by Roberts, Samantha A, Allen, Jeff D, Sigal, Ellen V

“…The US Food and Drug Administration is often criticized as inefficient compared to its European counterpart, the European Medicines Agency. This criticism is…”
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RivR and the small RNA RivX: the missing links between the CovR regulatory cascade and the Mga regulon by Roberts, Samantha A, Scott, June R

“…The CovR/S two-component system regulates the transcription of many genes that are crucial for the virulence of Streptococcus pyogenes (group A Streptococcus,…”
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Developing a post-treatment survivorship care plan to help breast cancer survivors understand their fertility by Gorman, Jessica R., Julian, Anne K., Roberts, Samantha A., Romero, Sally A. D., Ehren, Jennifer L., Krychman, Michael L., Boles, Sarah G., Mao, Jun, Irene Su, H.

“…Purpose Reproductive-aged breast cancer survivors (BCS) who have completed initial cancer treatment frequently want to know about their future fertility…”
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MP25-08 CAN RESIDENTS BE PRODUCTIVE IN A MONTH RESEARCH ROTATION? IMPACT OF A DEDICATED RESEARCH ROTATION ON RESIDENT PRODUCTIVITY AND ATTITUDES TOWARDS RESEARCH by Posid, Tasha, Roberts, Samantha A., Scimeca, Alicia, Khuhro, Aliza, Diab, Dinah, Denis-Diaz, Dairon, Ballinger, Jennifer, Moore, Courtenay K., Sharp, David S., Lee, Cheryl T.

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"All of the things to everyone everywhere": A mixed methods analysis of community perspectives on equitable access to monoclonal antibody treatment for COVID-19 by Bethany M Kwan, Chelsea Sobczak, Carol Gorman, Samantha Roberts, Vanessa Owen, Matthew K Wynia, Adit A Ginde, Griselda Pena-Jackson, Owen Ziegler, Lisa Ross DeCamp

“…BackgroundNeutralizing monoclonal antibody (mAb) treatment for COVID-19 prevents hospitalization and death but is underused, especially in racial/ethnic…”
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Adoptive transfer of islet antigen-autoreactive T cell clones to transgenic NOD.Ea(d)mice induces diabetes indicating a lack of I-E mediated protection against activated effector T cells by Roberts, Samantha A, Barbour, Gene, Matarrese, Marissa R, Mason, David L, Leiter, Edward H, Haskins, Kathryn, Hanson, Matthew S

“…Transgenic insertion of the MHC class II Ea(d)gene in NOD mice restores I-E expression and prevents T-cell-mediated autoimmune diabetes (IDDM). The specific…”
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Unraveling the Regulatory Network in Streptococcus pyogenes: the Global Response Regulator CovR Represses rivA Directly[white triangle down] by Roberts, Samantha A, Churchward, Gordon G, Scott, June R

“…The response regulator CovR acts as a master regulator of virulence in Streptococcus pyogenes by repressing transcription of approximately 15% of the group A…”
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Unraveling the CovR regulatory network of Streptococcus pyogenes by Roberts, Samantha A

“…Streptococcus pyogenes (Group A Streptococcus; GAS) is a significant Gram-positive bacterium responsible for a wide array of infections in humans. GAS is the…”
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Adoptive transfer of islet antigen–autoreactive T cell clones to transgenic NOD.Eadmice induces diabetes indicating a lack of I-E mediated protection against activated effector T cells by Roberts, Samantha A, Barbour, Gene, Matarrese, Marissa R, Mason, David L, Leiter, Edward H, Haskins, Kathryn, Hanson, Matthew S

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