Search Results - "Roberts, SA"

The role of nonrandomized trials in the evaluation of oncology drugs by Simon, R, Blumenthal, GM, Rothenberg, ML, Sommer, J, Roberts, SA, Armstrong, DK, LaVange, LM, Pazdur, R

“…Although randomized trials provide the most reliable evidence of a drug's safety and efficacy, there are situations where randomized trials are not possible or…”
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Towards single embryo transfer? Modelling clinical outcomes of potential treatment choices using multiple data sources: predictive models and patient perspectives by Roberts, Sa, McGowan, L, Hirst, Wm, Brison, Dr, Vail, A, Lieberman, Ba

“…In vitro fertilisation (IVF) treatments involve an egg retrieval process, fertilisation and culture of the resultant embryos in the laboratory, and the…”
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Obtaining tissue from the mediastinum: endoscopic ultrasound guided transoesophageal biopsy by ROBERTS, S A

“…Despite small patient numbers, in the only comparative study of EUS-FNA with mediastinoscopy to date Serna et al reasonably concluded that the techniques may…”
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Radiation-induced micronucleus induction in lymphocytes identifies a high frequency of radiosensitive cases among breast cancer patients: a test for predisposition? by SCOTT, D, BARBER, J. B. P, LEVINE, E. L, BURRILL, W, ROBERTS, S. A

“…Enhanced sensitivity to the chromosome-damaging effects of ionizing radiation is a feature of many cancer-predisposing conditions. We previously showed that…”
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Replacing sedentary time with sleep, light, or moderate-to-vigorous physical activity: effects on self-regulation and executive functioning by Fanning, J., Porter, G., Awick, E. A., Ehlers, D. K., Roberts, S. A., Cooke, G., Burzynska, A. Z., Voss, M. W., Kramer, A. F., McAuley, E.

“…Recent attention has highlighted the importance of reducing sedentary time for maintaining health and quality of life. However, it is unclear how changing…”
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G616 “We want to influence”: An evaluation of the national health service England youth forum by Whiting, LS, Roberts, SA

“…AimsPresentation aim: To provide an overview of a qualitative evaluation study of the National Health Service England Youth Forum [NHSEYF]…”
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The independence of intrinsic radiosensitivity as a prognostic factor for patient response to radiotherapy of carcinoma of the cervix by WEST, C. M. L, DAVIDSON, S. E, ROBERTS, S. A, HUNTER, R. D

“…A study was made of the prognostic value of pretreatment measurements of tumour radiosensitivity (surviving fraction at 2 Gy, SF2) in 128 patients with stage…”
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Future acceptance of adolescent human papillomavirus vaccination: A survey of parental attitudes by Brabin, Loretta, Roberts, Stephen A., Farzaneh, Farah, Kitchener, Henry C.

“…The main target group for vaccination against human papillomavirus (HPV), the sexually transmitted virus that causes cervical cancer, will be young…”
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Epidemiology of posttransplantation lymphoproliferative disorder in adult renal transplant recipients by Morton, Muir, Coupes, Beatrice, Roberts, Stephen A, Klapper, Paul E, Byers, Richard J, Vallely, Pamela J, Ryan, Kate, Picton, Michael L

“…There is little information in the literature describing the relationship between posttransplantation lymphoproliferative disorder (PTLD) incidence and…”
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Design and analysis of clinical trials with clustering effects due to treatment by Roberts, Chris, Roberts, Stephen A

“…Where patients receive therapy as a group, there are good theoretical reasons to believe that variation in the outcome will be smaller for patients treated in…”
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Thought disorder in mid-childhood as a predictor of adulthood diagnostic outcome: findings from the New York High-Risk Project by Gooding, D C, Ott, S L, Roberts, S A, Erlenmeyer-Kimling, L

“…Thought disorder has been proposed as an indicator of schizotypy, which is considered to be necessary but not sufficient for the development of schizophrenia…”
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Mucosal lactoferrin response to genital tract infections is associated with iron and nutritional biomarkers in young Burkinabé women by Roberts, S. A., Brabin, L., Diallo, S., Gies, S., Nelson, A., Stewart, C., Swinkels, D. W., Geurts-Moespot, A. J., Kazienga, A., Ouedraogo, S., D’Alessandro, U., Tinto, H., Brabin, B. J.

“…Background/Objectives The iron-binding affinity of vaginal lactoferrin (Lf) reduces iron available to genital pathogens. We describe host reproductive,…”
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Enhancing resilience and self-efficacy in the parents of children with disabilities and complex health needs by Whiting, M., Nash, A.S., Kendall, S., Roberts, S.A.

“…AimThe principal aim of this study was to develop, pilot and evaluate an intervention intended to support the development of resilience and self-efficacy in…”
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Clinical failures associated with rpoB mutations in phenotypically occult multidrug-resistant Mycobacterium tuberculosis by Williamson, D. A., Roberts, S. A., Bower, J. E., Vaughan, R., Newton, S., Lowe, O., Lewis, C. A., Freeman, J. T.

“…SETTING: Recently, Mycobacterium tuberculosis isolates have been described that test phenotypically susceptible to rifampicin (RMP) yet harbour genotypic rpoB…”
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Epstein–Barr Virus Infection in Adult Renal Transplant Recipients by Morton, M., Coupes, B., Roberts, S. A., Johnson, S. L., Klapper, P. E., Vallely, P. J., Picton, M. L.

“…Epstein–Barr virus (EBV) DNAemia in the first year posttransplantation has been studied extensively. There is a paucity of information on prevalence and…”
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Clinical characteristics and outcomes of patients with vancomycin-susceptible Enterococcus faecalis and Enterococcus faecium bacteraemia—a five-year retrospective review by McBride, S. J, Upton, A, Roberts, S. A

“…The purpose of this study was to assess the epidemiology and outcomes of enterococcal bacteraemia. A retrospective review of demographic, microbiological and…”
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Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover by Brison, D.R., Houghton, F.D., Falconer, D., Roberts, S.A., Hawkhead, J., Humpherson, P.G., Lieberman, B.A., Leese, H.J.

“…BACKGROUND: IVF is limited by low success rates and an unacceptably high multiple pregnancy rate. These outcomes would be improved significantly if a single…”
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Human papillomavirus vaccination and social inequality: results from a prospective cohort study by ROBERTS, S. A., BRABIN, L., STRETCH, R., BAXTER, D., ELTON, P., KITCHENER, H., McCANN, R.

“…We investigated the effect of social inequalities on the uptake of human papillomavirus (HPV) vaccination, combining data from a feasibility study conducted in…”
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Toxicodynamics of Itraconazole: Implications for Therapeutic Drug Monitoring by Lestner, Jodi M., Roberts, Steven A., Moore, Caroline B., Howard, Susan J., Denning, David W., Hope, William W.

“…We explored concentration-toxicity relationships for itraconazole among 216 patients. Logistic regression revealed a progressive increase in the probability of…”
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Drug metabolism and pharmacokinetics in drug discovery by Roberts, Simon A

“…The discovery and development of new drugs seems to be an inefficient process, since too few new chemical entities (NCEs) successfully make it to the market…”
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