Search Results - "Roberts, Roland G"

Trees as a metaphor to understand relationships in biology by Roberts, Roland G

“…The phylogenetic tree has been a core conceptual tool for evolutionary biology for nearly 200 years. This editorial explores the role of the tree as a…”
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Addressing biodiversity loss by building a shared future by Roberts, Roland G

“…As the UN International Day for Biological Diversity enters its twentieth year, we take stock of recent developments and trends in biodiversity research and…”
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The first six years of meta-research at PLOS Biology by Roberts, Roland G

“…Meta-research involves the interrogation of every stage of the research lifecycle, from conception to publication and dissemination. Looking back over the…”
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Mutation of the RAD51C gene in a Fanconi anemia-like disorder by Hanenberg, Helmut, Schindler, Detlev, Mathew, Christopher G, Vaz, Fiona, Schuster, Beatrice, Barker, Karen, Wiek, Constanze, Erven, Verena, Neveling, Kornelia, Endt, Daniela, Kesterton, Ian, Autore, Flavia, Fraternali, Franca, Freund, Marcel, Hartmann, Linda, Grimwade, David, Roberts, Roland G, Schaal, Heiner, Mohammed, Shehla, Rahman, Nazneen

“…Fanconi anemia (FA) is a rare chromosomal-instability disorder associated with a variety of developmental abnormalities, bone marrow failure and predisposition…”
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Good Amyloid, Bad Amyloid-What's the Difference? by Roberts, Roland G

“…Why do some amyloids cause serious neurodegenerative diseases, while others have important biological functions? A new study of the functional amyloid Orb2…”
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Mitochondria-A billion years of cohabitation by Roberts, Roland G

“…The authors show that this shifts the balance, favouring the early set-aside of the cells from which breeding occurs (the germline), and thereby limiting the…”
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Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility by Parkes, Miles, Barrett, Jeffrey C, Prescott, Natalie J, Tremelling, Mark, Anderson, Carl A, Fisher, Sheila A, Roberts, Roland G, Nimmo, Elaine R, Cummings, Fraser R, Soars, Dianne, Drummond, Hazel, Lees, Charlie W, Khawaja, Saud A, Bagnall, Richard, Burke, Denis A, Todhunter, Catherine E, Ahmad, Tariq, Onnie, Clive M, McArdle, Wendy, Strachan, David, Bethel, Graeme, Bryan, Claire, Lewis, Cathryn M, Deloukas, Panos, Forbes, Alastair, Sanderson, Jeremy, Jewell, Derek P, Satsangi, Jack, Mansfield, John C, Cardon, Lon, Mathew, Christopher G

“…A genome-wide association scan in individuals with Crohn's disease by the Wellcome Trust Case Control Consortium detected strong association at four novel…”
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Living Life on a Magnet by Roberts, Roland G

“…[...]bacteria from the Northern and Southern Hemispheres tend to have opposite magnetotactic swimming polarities to cater for the opposing inclination of the…”
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Nesprin-1 and -2 are involved in the pathogenesis of Emery–Dreifuss muscular dystrophy and are critical for nuclear envelope integrity by Zhang, Qiuping, Bethmann, Cornelia, Worth, Nathalie F., Davies, John D., Wasner, Christina, Feuer, Anja, Ragnauth, Cassandra D., Yi, Qijian, Mellad, Jason A., Warren, Derek T., Wheeler, Matthew A., Ellis, Juliet A., Skepper, Jeremy N., Vorgerd, Matthias, Schlotter-Weigel, Beate, Weissberg, Peter L., Roberts, Roland G., Wehnert, Manfred, Shanahan, Catherine M.

“…Emery–Dreifuss muscular dystrophy (EDMD) is a heterogeneous late-onset disease involving skeletal muscle wasting and heart defects caused, in a minority of…”
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Toxoplasma's Taste for Exotic Fat by Roberts, Roland G

“…A new study reveals that an exotic lipid, phosphatidylthreonine, makes up a substantial proportion of the membrane of a widespread human parasite and is…”
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The Fitness Effects of Love by Roberts, Roland G

“…A study of zebra finches reveals the potential advantages of idiosyncratic mate choice in monogamous animal species. Read the Research Article…”
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Intractable Tangles in the Bird Family Tree by Roberts, Roland G

“…Rapid sequential speciation events can outpace the fixation of genetic variants, resulting in a family tree that lacks clear branching patterns. A new study of…”
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Take Pax6 for a Cortical 6-Pack by Roberts, Roland G

“…This synopsis examines the implications of a new study that imposes primate-like expression of the transcription factor Pax6 on the developing mouse cortex and…”
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Lewontin's paradox resolved? In larger populations, stronger selection erases more diversity by Roberts, Roland G

“…A new study uses a massive comparative population genetics dataset to explore why the neutral genetic diversity of a species does not have a simple…”
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Symbiosis plasmids bring their own mutagen to the wedding party by Roberts, Roland G

“…  [...]to explore whether stress-induced mutagenesis was a peculiarity of the Cupriavidus symbiosis plasmid, the authors performed a survey of more than 300…”
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Chimps, Humans, and the Hominid Struggle against Viruses by Roberts, Roland G

“…  In the case of class I MHCs, positive recognition by a passing cytotoxic T cell can result in the peptide-displaying cell (and its viral inhabitants) being…”
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Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins by Autore, Flavia, Pfuhl, Mark, Quan, Xueping, Williams, Aisling, Roberts, Roland G, Shanahan, Catherine M, Fraternali, Franca

“…Nesprin-1 and nesprin-2 are nuclear envelope (NE) proteins characterized by a common structure of an SR (spectrin repeat) rod domain and a C-terminal…”
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Flagging the fatty acid ferryman by Roberts, Roland G

“…Fatty acids made in chloroplasts must be exported into the rest of the cell to be converted into commercially important plant oils. A new study identifies FAX1…”
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The blind men and the Piwi elephant--opening a can of worms by Roberts, Roland G

“…  Gratifyingly, the worm version of the Piwi protein (PRG-1) was also missing outside Clade V, as was HENN-1, the enzyme that sticks the characteristic methyl…”
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What goes "99-thump?" by Roberts, Roland G

“…  Together with some of the more conservative insect genomes (silk moth, red flour beetle) and that of the crustacean water flea, this will help fill in our…”
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