Search Results - "Roberts, Helen C"
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Development and validation of a Hospital Frailty Risk Score focusing on older people in acute care settings using electronic hospital records: an observational study
Published in The Lancet (British edition) (05-05-2018)“…Older people are increasing users of health care globally. We aimed to establish whether older people with characteristics of frailty and who are at risk of…”
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A systematic review of the evidence for deprescribing interventions among older people living with frailty
Published in BMC geriatrics (17-04-2021)“…Older people living with frailty are often exposed to polypharmacy and potential harm from medications. Targeted deprescribing in this population represents an…”
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Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS)
Published in Age and ageing (01-05-2013)“…sarcopenia is associated with adverse health outcomes. The aim of this study was to describe the prevalence of sarcopenia in community-dwelling older people in…”
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Comprehensive geriatric assessment in primary care: a systematic review
Published in Aging clinical and experimental research (01-02-2020)“…Background Comprehensive geriatric assessment (CGA) involves the multidimensional assessment and management of an older person. It is well described in…”
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The Challenge of Managing Undernutrition in Older People with Frailty
Published in Nutrients (10-04-2019)“…Many older people with frailty are at risk of malnutrition and poor health, yet there is evidence that improving nutrition and weight loss can reduce frailty…”
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Nutrition and Frailty: Opportunities for Prevention and Treatment
Published in Nutrients (01-07-2021)“…Frailty is a syndrome of growing importance given the global ageing population. While frailty is a multifactorial process, poor nutritional status is…”
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Perceptions of people with Parkinson's and their caregivers of falling and falls-related healthcare services- a qualitative study
Published in PloS one (26-10-2022)“…Falls are common in Parkinson's disease, and a recognised research priority. Falls lead to physical and psychological morbidity in people with Parkinson's…”
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Exercise- and strategy-based physiotherapy-delivered intervention for preventing repeat falls in people with Parkinson's: the PDSAFE RCT
Published in Health technology assessment (Winchester, England) (01-07-2019)“…People with Parkinson's disease are twice as likely to experience a fall as a healthy older person, often leading to debilitating effects on confidence,…”
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Assessment and Treatment of the Anorexia of Aging: A Systematic Review
Published in Nutrients (11-01-2019)“…(1) Background: Appetite loss in older people, the 'Anorexia of Aging' (AA), is common, associated with under-nutrition, sarcopenia, and frailty and yet…”
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What are the modifiable factors of treatment burden and capacity among people with Parkinson's disease and their caregivers: A qualitative study
Published in PloS one (30-03-2023)“…People with long-term conditions must complete many healthcare tasks such as take medications, attend appointments, and change their lifestyle. This treatment…”
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The efficacy of gemcitabine and docetaxel chemotherapy for the treatment of relapsed and refractory osteosarcoma: A systematic review and pre‐clinical study
Published in Cancer medicine (Malden, MA) (01-09-2024)“…Introduction Osteosarcoma is the most common primary malignancy of the bone. There is a lack of effective treatments for patients who experience relapsed…”
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Associations Between Objectively Measured Physical Activity, Body Composition and Sarcopenia: Findings from the Hertfordshire Sarcopenia Study (HSS)
Published in Calcified tissue international (01-09-2018)“…Regular physical activity (PA) is associated with reduced risk of the development and progression of musculoskeletal, metabolic and vascular disease. However,…”
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Establishment and Characterization of Single and Triple‐Agent Resistant Osteosarcoma Cell Lines
Published in Advanced biology (01-02-2023)“…Two human osteosarcoma cell lines (MG‐63 and HOS‐143B) are developed into drug‐resistant models using a short‐term drug exposure and recovery in drug‐free…”
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Pasteurella sp. associated with fatal septicaemia in six African elephants
Published in Nature communications (25-10-2023)“…The sudden mortality of African elephants ( Loxodonta africana ) in Botswana and Zimbabwe in 2020 provoked considerable public interest and speculation…”
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The feasibility of assessing frailty and sarcopenia in hospitalised older people: a comparison of commonly used tools
Published in BMC geriatrics (15-02-2019)“…Frailty and sarcopenia are common amongst hospitalised older people and associated with poor healthcare outcomes. Widely recognised tools for their…”
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The composition of the gut microbiome differs among community dwelling older people with good and poor appetite
Published in Journal of cachexia, sarcopenia and muscle (01-04-2021)“…Background Anorexia of ageing is common and important in the development of sarcopenia in older individuals. Links have been proposed between the gut…”
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What makes a multidisciplinary medication review and deprescribing intervention for older people work well in primary care? A realist review and synthesis
Published in BMC geriatrics (25-09-2023)“…A third of older people take five or more regular medications (polypharmacy). Conducting medication reviews in primary care is key to identify and reduce/ stop…”
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Understanding support systems for Parkinson's disease management in community settings: A cross‐national qualitative study
Published in Health expectations : an international journal of public participation in health care and health policy (01-04-2023)“…Background Health and social care systems face difficulties in managing multimorbidity, disease burden and complex needs in long‐term conditions such as…”
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Grip strength and its determinants among older people in different healthcare settings
Published in Age and ageing (01-03-2014)“…low muscle strength is central to geriatric syndromes including sarcopenia and frailty. It is well described in community-dwelling older people, but the…”
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Implementation of grip strength measurement in medicine for older people wards as part of routine admission assessment: identifying facilitators and barriers using a theory-led intervention
Published in BMC geriatrics (22-03-2018)“…Low grip strength in older inpatients is associated with poor healthcare outcomes including longer length of stay and mortality. Measuring grip strength is…”
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