Search Results - "Roberts, Eugene L."

Energy Substrates for Neurons During Neural Activity: A Critical Review of the Astrocyte-Neuron Lactate Shuttle Hypothesis by Chih, Ching-Ping, Roberts, Eugene L

“…Glucose had long been thought to fuel oxidative metabolism in active neurons until the recently proposed astrocyte-neuron lactate shuttle hypothesis (ANLSH)…”
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Ethnic differences in carotid artery diameter and stiffness: The Northern Manhattan Study by Markert, Matthew S, Della-Morte, David, Cabral, Digna, Roberts, Eugene L, Gardener, Hannah, Dong, Chuanhui, Wright, Clinton B, Elkind, Mitchell S.V, Sacco, Ralph L, Rundek, Tatjana

“…Abstract Objective Race/ethnic differences in carotid arterial function and structure exist among those with cerebrovascular disease, but whether differences…”
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Do active cerebral neurons really use lactate rather than glucose? by Chih, Ching-Ping, Lipton, Peter, Roberts, Eugene L

“…Glucose has long been considered the substrate for neuronal energy metabolism in the brain. Recently, an alternative explanation of energy metabolism in the…”
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Rimantadine in Parkinson's disease patients experiencing peripheral adverse effects from amantadine: Report of a case series by Singer, Carlos, Papapetropoulos, Spiridon, Gonzalez, Manuel A., Roberts, Eugene L., Lieberman, Abraham

“…We report our experience with 7 consecutive patients with Parkinson's disease (PD) who received rimantadine (the α‐methyl derivative of amantadine) in…”
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Comparison of glucose and lactate as substrates during NMDA-induced activation of hippocampal slices by Chih, Ching-Ping, He, Jiao, Sly, Tanner S, Roberts, Eugene L

“…It has been postulated that lactate released from astrocytes may be the preferred metabolic substrate for neurons, particularly during intense neuronal…”
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Rat hippocampal slices need bicarbonate for the recovery of synaptic transmission after anoxia by Roberts, Eugene L, He, Jiao, Chih, Ching-Ping

“…The purpose of this study was to see how the nominal removal of bicarbonate (HCO 3 −) from the extracellular space of brain tissue influenced recovery of brain…”
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The pH buffering capacity of hippocampal slices from young adult and aged rats by Roberts, Eugene L, Chih, Ching-Ping

“…We examined the hypothesis that aging alters the capacity of brain tissue to buffer intracellular pH changes. Intracellular buffering power was determined in…”
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The influence of glucose on intracellular and extracellular pH in rat hippocampal slices during and after anoxia by Roberts, Eugene L, He, Jiao, Chih, Ching-Ping

“…In this study we investigated in rat hippocampal slices (1) how glucose availability affected tissue acidosis during and after anoxia, (2) whether the onset of…”
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Aging and the effects of MK-801 on anoxic damage in rat hippocampal slices by Roberts, Eugene L, Wisotzky, David, Chih, Ching-Ping

“…We examined whether age-related differences in N-methyl- d-aspartate (NMDA) receptor-mediated neurotoxicity contribute to the increased vulnerability of the…”
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A role for lactate released from astrocytes in energy production during neural activity? by Roberts, Eugene L, Chih, Ching-Ping

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pH and Brain Function by Roberts, Eugene L.

“…"pH and Brain Function" edited by Kai Kaila and Bruce R. Ransom is reviewed…”
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pH and Brain Function . Kai Kaila , Bruce R. Ransom by Roberts, Eugene L.

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Using Hippocampal Slices to Study How Aging Alters Ion Regulation in Brain Tissue by Roberts, Eugene L.

“…Aging alters ion regulation in brain tissue. This article describes methods useful for studying such age-related changes in the rat hippocampal slice…”
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The influence of age of pH regulation in hippocampal slices before, during, and after anoxia by Roberts, Jr, E L, Chih, C P

“…Changes in intracellular and extracellular pH may influence the vulnerability of brain tissue to anoxic or ischemic damage. In the present study, we…”
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Cases and Commentaries by Hodges, Louis W., Newton, Lisa H., Dunklee, Jerry, Roberts, Eugene L., Sikula, Andrew, Roberts, Chris

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Aging impairs regulation of intracellular pH in rat hippocampal slices by Roberts, Eugene L., Sick, Thomas J.

“…We investigated whether aging changed H + homeostasis in hippocampal slices bathed in HEPES buffer. Intracellular pH in hippocampal slices from rats aged 26–27…”
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Age-related alterations in energy metabolism contribute to the increased vulnerability of the aging brain to anoxic damage by Roberts, Eugene L., Chih, Ching-Ping

“…Aging increases the vulnerability of brain tissue to anoxia and ischemia. We investigated whether age-related alterations in energy metabolism underlie this…”
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Age-related changes in brain metabolism and vulnerability to anoxia by Roberts, Jr, E L, Chih, C P, Rosenthal, M

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Extracellular potassium ion activity and electrophysiology in the hippocampal slice: paradoxical recovery of synaptic transmission during anoxia by Sick, T J, Solow, E L, Roberts, Jr, E L

“…The relationship between extracellular potassium ion activity and neuronal excitability during anoxia was investigated in hippocampal slices in vitro…”
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Influence of age on the clearance of K + from the extracellular space of rat hippocampal slices by Roberts, Eugene L., Feng, Zi-Cai

“…We examined the hypotheses that aging alters the capacity of brain tissue to regulate extracellular K +activity (K o +), and that age-related decreases in…”
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