Search Results - "Roberts, Emma L"

CDK activity at the centrosome regulates the cell cycle by Roberts, Emma L., Greenwood, Jessica, Kapadia, Nitin, Auchynnikava, Tania, Basu, Souradeep, Nurse, Paul

“…In human cells and yeast, an intact “hydrophobic patch” substrate docking site is needed for mitotic cyclin centrosomal localization. A hydrophobic patch…”
Get full text

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase by Basu, Souradeep, Mak, Tiffany, Ulferts, Rachel, Wu, Mary, Deegan, Tom, Fujisawa, Ryo, Tan, Kang Wei, Lim, Chew Theng, Basier, Clovis, Canal, Berta, Curran, Joseph F, Drury, Lucy S, McClure, Allison W, Roberts, Emma L, Weissmann, Florian, Zeisner, Theresa U, Beale, Rupert, Cowling, Victoria H, Howell, Michael, Labib, Karim, Diffley, John F X

“…The COVID-19 pandemic has presented itself as one of the most critical public health challenges of the century, with SARS-CoV-2 being the third member of the…”
Get more information

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease by Canal, Berta, McClure, Allison W, Curran, Joseph F, Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Zeng, Jingkun, Bertolin, Agustina P, Milligan, Jennifer C, Basu, Souradeep, Drury, Lucy S, Deegan, Tom D, Fujisawa, Ryo, Roberts, Emma L, Basier, Clovis, Labib, Karim, Beale, Rupert, Howell, Michael, Diffley, John F X

“…SARS-CoV-2 is a coronavirus that emerged in 2019 and rapidly spread across the world causing a deadly pandemic with tremendous social and economic costs…”
Get more information

The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis by Basu, Souradeep, Roberts, Emma L., Jones, Andrew W., Swaffer, Matthew P., Snijders, Ambrosius P., Nurse, Paul

“…The cyclin-dependent kinases (CDKs) are the major cell-cycle regulators that phosphorylate hundreds of substrates, controlling the onset of S phase and M phase…”
Get full text

Solution Structures of Apo and Holo Biotinyl Domains from Acetyl Coenzyme A Carboxylase of Escherichia coli Determined by Triple-Resonance Nuclear Magnetic Resonance Spectroscopy by Roberts, Emma L, Shu, Ningcheng, Howard, Mark J, Broadhurst, R. William, Chapman-Smith, Anne, Wallace, John C, Morris, Tim, Cronan, John E, Perham, Richard N

“…A subgene encoding the 87 C-terminal amino acids of the biotinyl carboxy carrier protein (BCCP) from the acetyl CoA carboxylase of Escherichia coli was…”
Get full text

Three-dimensional Structure of the Lipoyl Domain from the Dihydrolipoyl Succinyltransferase Component of the 2-Oxoglutarate Dehydrogenase Multienzyme Complex of Escherichia coli by Ricaud, Paul M., Howard, Mark J., Roberts, Emma L., Broadhurst, R.William, Perham, Richard N.

“…A sub-gene encoding the lipoyl domain of the dihydrolipoyl succinyltransferase polypeptide chain of the 2-oxoglutarate dehydrogenase multien zyme complex of…”
Get full text

Three-dimensional Structure of the Lipoyl Domain from the Dihydrolipoyl Succinyltransferase Component of the 2-Oxoglutarate Dehydrogenase Multienzyme Complex ofEscherichia coli by Ricaud, Paul M., Howard, Mark J., Roberts, Emma L., Broadhurst, R.William, Perham, Richard N.

Get full text