Search Results - "Roberts, DW"

Chronic deep brain stimulation for the treatment of tremor in multiple sclerosis: review and case reports by Wishart, H A, Roberts, D W, Roth, R M, McDonald, B C, Coffey, D J, Mamourian, A C, Hartley, C, Flashman, L A, Fadul, C E, Saykin, A J

“…Background: Deep brain stimulation (DBS) offers a non-ablative alternative to thalamotomy for the surgical treatment of medically refractory tremor in multiple…”
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Mechanisms of acetaminophen-induced liver necrosis by Hinson, Jack A, Roberts, Dean W, James, Laura P

“…Although considered safe at therapeutic doses, at higher doses, acetaminophen produces a centrilobular hepatic necrosis that can be fatal. Acetaminophen…”
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Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure by JAMES, Laura P, LETZIG, Lynda, SIMPSON, Pippa M, CAPPARELLI, Edmund, ROBERTS, Dean W, HINSON, Jack A, DAVERN, Timothy J, LEE, William M

“…Acetaminophen (APAP)-induced liver toxicity occurs with formation of APAP-protein adducts. These adducts are formed by hepatic metabolism of APAP to N -acetyl-…”
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Metarhizium spp., cosmopolitan insect-pathogenic fungi: mycological aspects by Roberts, Donald W, St Leger, Raymond J

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Skin Sensitization:  Reaction Mechanistic Applicability Domains for Structure−Activity Relationships by Aptula, Aynur O, Patlewicz, Grace, Roberts, David W

“…The prediction of skin sensitization potential with minimum animal testing is currently of great importance in light of forthcoming legislation. A number of…”
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In Silico Prediction of Aqueous Solubility: The Solubility Challenge by Hewitt, M, Cronin, M. T. D, Enoch, S. J, Madden, J. C, Roberts, D. W, Dearden, J. C

“…The dissolution of a chemical into water is a process fundamental to both chemistry and biology. The persistence of a chemical within the environment and the…”
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Current status of methods for defining the applicability domain of (Quantitative) structure-activity relationships : The report and recommendations of ECVAM workshop 52 by NETZEVA, Tatiana I, WORTH, Andrew P, MYATT, Glenn, NIKOLOVA-JELIAZKOVA, Nina, PATLEWICZ, Grace Y, PERKINS, Roger, ROBERTS, David W, SCHULTZ, Terry W, STANTON, David T, VAN DE SANDT, Johannes J. M, TONG, Weida, VEITH, Gilman, ALDENBERG, Tom, YANG, Chihae, BENIGNI, Romualdo, CRONIN, Mark T. D, GRAMATICA, Paola, JAWORSKA, Joanna S, KAHN, Scott, KLOPMAN, Gilles, MARCHANT, Carol A

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Neutron Rem Detector Response Changes due to Activation of Components by Hogue, M.G, Roberts, D.W, Burkett, J.L

“…ABSTRACTThe relative response of neutron rem detectors has previously been shown to increase after prolonged exposure to a neutron flux. This increase has been…”
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Dopamine efflux in the rat striatum evoked by electrical stimulation of the subthalamic nucleus: potential mechanism of action in Parkinson's disease by Lee, Kendall H., Blaha, Charles D., Harris, Brent T., Cooper, Shannon, Hitti, Frederick L., Leiter, James C., Roberts, David W., Kim, Uhnoh

“…The precise mechanism whereby continuous high‐frequency electrical stimulation of the subthalamic nucleus ameliorates motor symptoms of Parkinson's disease is…”
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Neurotransmitter release from high-frequency stimulation of the subthalamic nucleus by LEE, Kendall H, CHANG, Su-Youne, ROBERTS, David W, KIM, Uhnoh

“…High-frequency stimulation (HFS) delivered through implanted electrodes in the subthalamic nucleus (STN) has become an established treatment for Parkinson…”
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Non-enzymatic glutathione reactivity and in vitro toxicity: A non-animal approach to skin sensitization by Aptula, Aynur O., Patlewicz, Grace, Roberts, David W., Schultz, T.W.

“…The development of non-animal methods to predict the potential of chemicals to cause skin sensitization is of great importance. On the basis of many published…”
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Intraoperative brain shift and deformation: a quantitative analysis of cortical displacement in 28 cases by Roberts, D W, Hartov, A, Kennedy, F E, Miga, M I, Paulsen, K D

“…A quantitative analysis of intraoperative cortical shift and deformation was performed to gain a better understanding of the nature and extent of this problem…”
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Variability in conidial thermotolerance of Metarhizium anisopliae isolates from different geographic origins by Rangel, Drauzio E.N., Braga, Gilberto U.L., Anderson, Anne J., Roberts, Donald W.

“…Notable variability in thermotolerance was found among conidia of 16 isolates of the insect-pathogenic fungi Metarhizium anisopliae var. anisopliae and one M…”
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The aquatic toxicity of anionic surfactants to Daphnia magna—A comparative QSAR study of linear alkylbenzene sulphonates and ester sulphonates by Hodges, Geoff, Roberts, David W., Marshall, Stuart J., Dearden, John C.

“…This paper develops quantitative structure activity relationships (QSARs) for the acute aquatic toxicity of the anionic surfactants linear alkylbenzene…”
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Metabolism of Biochanin A and Formononetin by Human Liver Microsomes in Vitro by Tolleson, William H, Doerge, Daniel R, Churchwell, Mona I, Marques, M. Matilde, Roberts, Dean W

“…Biochanin A and formononetin are abundant in legumes. These proestrogenic isoflavones can be converted by 4‘-O-demethylation to the more potent phytoestrogens…”
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How should leaf area, sapwood area and stomatal conductance vary with tree height to maximize growth? by Buckley, T.N, Roberts, D.W

“…Conventional wisdom holds that the ratio of leaf area to sapwood area (L/S) should decline during height (H) growth to maintain hydraulic homeostasis and…”
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Stereopsis-guided brain shift compensation by Hai Sun, Lunn, K.E., Farid, H., Ziji Wu, Roberts, D.W., Hartov, A., Paulsen, K.D.

“…Brain deformation models have proven to be a powerful tool in compensating for soft tissue deformation during image-guided neurosurgery. The accuracy of these…”
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Structure−Toxicity Relationships for the Effects to Tetrahymena pyriformis of Aliphatic, Carbonyl-Containing, α,β-Unsaturated Chemicals by Schultz, T. Wayne, Netzeva, Tatiana I, Roberts, David W, Cronin, Mark T. D

“…Toxicity data for 82 aliphatic chemicals with an α,β-unsaturated substructure were compiled. Toxicity was assessed in the 2-day Tetrahymena pyriformis…”
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Application of Octanol/Water Partition Coefficients in Surfactant Science:  A Quantitative Structure−Property Relationship for Micellization of Anionic Surfactants by Roberts, David W

“…The octanol/water partition coefficient, usually as its logarithm, log P, is widely used as a hydrophobicity parameter in modeling pharmacological and…”
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Factors influencing wear and osteolysis in press-fit condylar modular total knee replacements by Fehring, Thomas K, Murphy, Jeffrey A, Hayes, T David, Roberts, Donald W, Pomeroy, Donald L, Griffin, William L

“…The purpose of this study was to determine the factors influencing wear and osteolysis in patients who have had total knee arthroplasty with the Press-Fit…”
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