Search Results - "Roberts, Catherine H"
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Feasibility of intravenous vitamin C supplementation in allogeneic hematopoietic cell transplant recipients
Published in EJHaem (01-10-2024)“…Introduction Intravenous vitamin C was administered following hematopoietic stem cell transplant to mitigate nonrelapse mortality (NRM) in a Phase II clinical…”
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Sequence homology between HLA-bound cytomegalovirus and human peptides: A potential trigger for alloreactivity
Published in PloS one (11-08-2017)“…Human cytomegalovirus (hCMV) reactivation may often coincide with the development of graft-versus-host-disease (GVHD) in stem cell transplantation (SCT)…”
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Epigenetic induction of adaptive immune response in multiple myeloma: sequential azacitidine and lenalidomide generate cancer testis antigen-specific cellular immunity
Published in British journal of haematology (01-09-2012)“…Summary Patients with multiple myeloma (MM) undergoing high dose therapy and autologous stem cell transplantation (SCT) remain at risk for disease progression…”
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In silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem-Cell Transplant Donors and Recipients: Understanding the Quantitative Immunobiology of Allogeneic Transplantation
Published in Frontiers in immunology (2014)“…Donor T-cell mediated graft versus host (GVH) effects may result from the aggregate alloreactivity to minor histocompatibility antigens (mHA) presented by the…”
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Gametocyte carriage in Plasmodium falciparum-infected travellers
Published in Malaria journal (24-01-2013)“…Gametocytes are the sexual stage of Plasmodium parasites. The determinants of gametocyte carriage have been studied extensively in endemic areas, but have…”
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Stem cell transplantation as a dynamical system: are clinical outcomes deterministic?
Published in Frontiers in immunology (03-12-2014)“…Outcomes in stem cell transplantation (SCT) are modeled using probability theory. However, the clinical course following SCT appears to demonstrate many…”
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Digital Polymerase Chain Reaction Paired with High-Speed Atomic Force Microscopy for Quantitation and Length Analysis of DNA Length Polymorphisms
Published in ACS nano (24-11-2020)“…DNA length polymorphisms are found in many serious diseases, and assessment of their length and abundance is often critical for accurate diagnosis. However,…”
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High dose valacyclovir for cytomegalovirus prophylaxis following allogeneic hematopoietic cell transplantation
Published in Journal of oncology pharmacy practice (01-01-2023)“…Introduction Cytomegalovirus (CMV) is one of the most common and clinically significant viral infections following allogeneic hematopoietic cell…”
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New opportunities for control of dengue virus
Published in Current opinion in infectious diseases (01-12-2013)“…PURPOSE OF REVIEWDengue is a rapidly spreading vector-borne disease estimated to infect 400 million people worldwide. To date, there are no licensed treatments…”
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A multicenter report on the safety and efficacy of plerixafor based stem cell mobilization in children with malignant disorders
Published in Transfusion (Philadelphia, Pa.) (01-03-2021)“…Background Pleraxifor for peripheral blood stem cell (PBSC) mobilization in children with malignancies is often given following failure of standard…”
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A Preliminary Investigation towards the Risk Stratification of Allogeneic Stem Cell Recipients with Respect to the Potential for Development of GVHD via Their Pre-Transplant Plasma Lipid and Metabolic Signature
Published in Cancers (25-07-2019)“…The clinical outcome of allogeneic hematopoietic stem cell transplantation (SCT) may be influenced by the metabolic status of the recipient following…”
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Low-dose splenic irradiation prior to hematopoietic cell transplantation in hypersplenic patients with myelofibrosis
Published in Leukemia & lymphoma (02-12-2017)Get full text
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The influence of lymphoid reconstitution kinetics on clinical outcomes in allogeneic stem cell transplantation
Published in Leukemia & lymphoma (02-12-2018)“…Lymphoid recovery following myeloablative stem cell transplantation (SCT) displays a logistic pattern of exponential growth followed by a plateau. Within this…”
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Whole exome sequencing to estimate alloreactivity potential between donors and recipients in stem cell transplantation
Published in British journal of haematology (01-08-2014)“…Summary Whole exome sequencing (WES) was performed on stem cell transplant donor‐recipient (D‐R) pairs to determine the extent of potential antigenic variation…”
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Distinct Oligoclonal T Cells Are Associated With Graft Versus Host Disease After Stem-Cell Transplantation
Published in Transplantation (15-05-2012)“…In patients with hematologic malignancies who receive stem-cell transplantation, donors' T cells can recognize minor histocompatibility antigens on recipient…”
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Dengue fever: a practical guide
Published in British journal of hospital medicine (London, England : 2005) (01-04-2012)Get full text
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Hepatotoxicity in the treatment of tuberculosis using moxifloxacin-containing regimens [Correspondence]
Published in The international journal of tuberculosis and lung disease (01-09-2011)“…Fluoroquinolones may be used as alternative anti-tuberculosis agents in subjects at high risk of, or experiencing, hepatotoxicity. super(1) A 2008 UK drug…”
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The Influence of Lymphoid Reconstitution Kinetics on Clinical Outcomes in Allogeneic Stem Cell Transplantation
Published in Biology of blood and marrow transplantation (01-03-2017)Get full text
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Dynamical System Modeling of Immune Reconstitution after Allogeneic Stem Cell Transplantation Identifies Patients at Risk for Adverse Outcomes
Published in Biology of blood and marrow transplantation (01-07-2015)“…Abstract Systems that evolve over time and follow mathematical laws as they evolve are called dynamical systems . Lymphocyte recovery and clinical outcomes in…”
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Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides Demonstrates Different Alloreactivity Potential in HLA-Matched and -Mismatched Donor–Recipient Pairs
Published in Biology of blood and marrow transplantation (01-05-2016)“…Abstract Immune reconstitution kinetics and subsequent clinical outcomes in HLA-matched recipients of allogeneic stem cell transplantation (SCT) are variable…”
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