Search Results - "Roberts, C.T."
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IFPA Award in Placentology Lecture: Complicated interactions between genes and the environment in placentation, pregnancy outcome and long term health
Published in Placenta (01-03-2010)“…Abstract Most research on the developmental origins of health and disease has implicated poor nutrition in the fetus, most often conferred by deficiencies in…”
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Journal Article Presentation -
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Placental expression of VEGF family mRNA in adverse pregnancy outcomes
Published in Placenta (Eastbourne) (01-06-2012)“…Abstract Introduction The pregnancy complications preeclampsia, gestational hypertension, small for gestational age infants (SGA) and pre-term birth (PTB)…”
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Distinct Actions of Insulin-Like Growth Factors (IGFs) on Placental Development and Fetal Growth: Lessons from Mice and Guinea Pigs
Published in Placenta (Eastbourne) (01-03-2008)“…Abstract Placental insufficiency is thought to be a key factor in many cases of intrauterine growth restriction which complicates about 6% of pregnancies in…”
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Journal Article Conference Proceeding -
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Use of Matrigel in culture affects cell phenotype and gene expression in the first trimester trophoblast cell line HTR8/SVneo
Published in Placenta (Eastbourne) (01-07-2012)“…Abstract There is inconsistent use of Matrigel for experiments with the HTR8/SVneo first trimester trophoblast and other cell lines. We quantified the effects…”
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The association of AGTR2 polymorphisms with preeclampsia and uterine artery bilateral notching is modulated by maternal BMI
Published in Placenta (Eastbourne) (01-01-2013)“…Abstract Introduction This study aimed to determine the association of AGTR1 and AGTR2 polymorphisms with preeclampsia and whether these are affected by…”
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Hypoxia-inducible factor-1α gene polymorphisms in early and late onset preeclampsia in Sinhalese women
Published in Placenta (Eastbourne) (01-07-2014)“…Abstract Introduction Early (EPE) and late (LPE) onset preeclampsia are increasingly being recognized as two distinct disorders. Placental vascular defects are…”
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How big is big enough? Population differences in pregnancy outcome
Published in Placenta (Eastbourne) (01-09-2014)Get full text
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Complex Interactions Between Hypoxia Inducible Factors, Insulin-Like Growth Factor-II and Oxygen in Early Murine Trophoblasts
Published in Placenta (Eastbourne) (01-11-2007)“…Abstract The human first trimester placenta experiences a low oxygen environment. The hypoxia inducible factors (HIFs) mediate the response to low oxygen,…”
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DNA damage and health in pregnancy
Published in Journal of reproductive immunology (01-05-2011)“…Abstract In healthy pregnancy reactive oxygen species and antioxidants remain in balance and DNA damage is repaired effectively. However, pregnancy is an…”
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Journal Article Conference Proceeding -
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New Light on Early Post-Implantation Pregnancy in the Mouse: Roles for Insulin-Like Growth Factor-II (IGF-II)?
Published in Placenta (Eastbourne) (01-04-2007)“…Abstract Successful placental development and the associated changes to the decidual vasculature during early pregnancy are critical to pregnancy outcome. This…”
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Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-gamma in inflammation in human adipose tissue
Published in International Journal of Obesity (01-09-2009)“…Background: Adipose tissue is a primary in vivo site of inflammation in obesity. Excess visceral adipose tissue (VAT), when compared to subcutaneous adipose…”
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Journal Article -
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A functional variant in the thrombospondin‐1 gene and the risk of small for gestational age infants
Published in Journal of thrombosis and haemostasis (01-11-2011)“…Introduction: Thrombospondin‐1 (TSP‐1) is a prothrombotic and anti‐angiogenic glycoprotein expressed in the placenta. A functional single nucleotide…”
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Distinct Patterns of Gene-Specific Methylation in Mammalian Placentas: Implications for Placental Evolution and Function
Published in Placenta (Eastbourne) (01-04-2010)“…Abstract The placenta has arisen relatively recently and is among the most rapidly evolving tissues in mammals. Several different placental barrier and…”
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Preeclampsia and intra-uterine growth restriction: the role of the father
Published in Journal of reproductive immunology (2010)Get full text
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Maternal Insulin-like Growth Factor-II Promotes Placental Functional Development Via the Type 2 IGF Receptor in the Guinea Pig
Published in Placenta (Eastbourne) (01-04-2008)“…Abstract In guinea pigs, maternal insulin-like growth factor (IGF) infusion in early-pregnancy enhances placental transport near-term, increasing fetal growth…”
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Ontogeny of Placental Structural Development and Expression of the Renin–Angiotensin System and 11β-HSD2 Genes in the Rabbit
Published in Placenta (Eastbourne) (01-07-2009)“…Abstract Common pregnancy complications are associated with impaired placental development. This study aimed to characterise the ontogeny of structural…”
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Maternal Serum Glycosylated Fibronectin as a Point-of-Care Biomarker for Assessment of Preeclampsia
Published in Obstetric anesthesia digest (01-12-2015)“…(Am J Obstet Gynecol. 2015;212:82.e1–82.e9)…”
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IFPA Meeting 2012 Workshop Report II: Epigenetics and imprinting in the placenta, growth factors and villous trophoblast differentiation, role of the placenta in regulating fetal exposure to xenobiotics during pregnancy, infection and the placenta
Published in Placenta (Eastbourne) (01-03-2013)“…Abstract Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialized topics. At IFPA meeting 2012 there were twelve…”
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IFPA Meeting 2009 Workshops Report
Published in Placenta (Eastbourne) (01-03-2010)“…Abstract Workshops are an important part of the annual meeting of the International Federation of Placenta Associations (IFPA). At IFPA Meeting 2009 diverse…”
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