Search Results - "Roberts, C. W"

Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences by Pugh, T J, Yu, W, Yang, J, Field, A L, Ambrogio, L, Carter, S L, Cibulskis, K, Giannikopoulos, P, Kiezun, A, Kim, J, McKenna, A, Nickerson, E, Getz, G, Hoffher, S, Messinger, Y H, Dehner, L P, Roberts, C W M, Rodriguez-Galindo, C, Williams, G M, Rossi, C T, Meyerson, M, Hill, D A

“…Pleuropulmonary blastoma is a rare childhood malignancy of lung mesenchymal cells that can remain dormant as epithelial cysts or progress to high-grade…”
Get full text

Activation of β-catenin/TCF targets following loss of the tumor suppressor SNF5 by Mora-Blanco, E L, Mishina, Y, Tillman, E J, Cho, Y-J, Thom, C S, Pomeroy, S L, Shao, W, Roberts, C W M

“…The SWI/SNF chromatin remodeling complex is a master regulator of developmental cell-fate decisions, although the key target pathways are poorly characterized…”
Get full text

Sequential expression of macrophage anti‐microbial/inflammatory and wound healing markers following innate, alternative and classical activation by Menzies, F. M., Henriquez, F. L., Alexander, J., Roberts, C. W.

“…Summary The present study examines the temporal dynamics of macrophage activation marker expression in response to variations in stimulation. We demonstrate…”
Get full text

Morphology and significance of the left ventricular collagen network in young patients with hypertrophic cardiomyopathy and sudden cardiac death by Shirani, Jamshid, Pick, Ruth, Roberts, William C, Maron, Barry J

“…BACKGROUND Hypertrophic cardiomyopathy (HCM) is a primary cardiac disease with a diverse clinical spectrum, in which many of the abnormal structural and…”
Get full text

Sex-Associated Hormones and Immunity to Protozoan Parasites by ROBERTS, Craig W, WALKER, William, ALEXANDER, James

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Evidence for the shikimate pathway in apicomplexan parasites by McLeod, Rima, Roberts, Fiona, Roberts, Craig W, Johnson, Jennifer J, Kyle, Dennis E, Krell, Tino, Coggins, John R, Coombs, Graham H, Milhous, Wilbur K, Tzipori, Saul, Ferguson, David J. P, Chakrabarti, Debopam

“…Parasites of the phylum Apicomplexa cause substantial morbidity, mortality and economic losses, and new medicines to treat them are needed urgently,. The…”
Get full text

Resistance of Leishmania donovani to Sodium Stibogluconate Is Related to the Expression of Host and Parasite γ-Glutamylcysteine Synthetase by CARTER, K. C, HUTCHISON, S, HENRIQUEZ, F. L, LEGARE, D, OUELLETTE, M, ROBERTS, C. W, MULLEN, A. B

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa by Roberts, C.W., McLeod, R., Rice, D.W., Ginger, M., Chance, M.L., Goad, L.J.

“…Current treatments for diseases caused by apicomplexan and trypanosomatid parasites are inadequate due to toxicity, the development of drug resistance and an…”
Get full text

Primary and Secondary Neoplasms of the Heart by Roberts, W C

“…Classification for cardiac neoplasms, their location and various specific benign or malignant primary cardiac neoplasms are discussed…”
Get full text

The rule of 5 and the rule of 7 in lipid-lowering by statin drugs by Roberts, W C

Get full text

CD8+ T cells are the major lymphocyte subpopulatlon involved in the protective immune response to Toxoplasma gondii in mice by PARKER, S. J., ROBERTS, C. W., ALEXANDER, J.

“…SUMMARY The ability of the major T cell subsets to adoptively transfer resistance to T. gondii infection was studied. Spleen cells harvested from mice with a…”
Get full text

Delivery of Antimicrobials into Parasites by Samuel, B. U., Hearn, B., Mack, D., Wender, P., Rothbard, J., Kirisits, M. J., Mui, E., Wernimont, S., Roberts, C. W., Muench, S. P., Rice, D. W., Prigge, S. T., Law, A. B., McLeod, R.

“…To eliminate apicomplexan parasites, inhibitory compounds must cross host cell, parasitophorous vacuole, and parasite membranes and cyst walls, making delivery…”
Get full text

The Toxoplasma gondii plastid replication and repair enzyme complex, PREX by Mukhopadhyay, A, Chen, C-Y, Doerig, C, Henriquez, F L, Roberts, C W, Barrett, M P

“…A plastid-like organelle, the apicoplast, is essential to the majority of medically and veterinary important apicomplexan protozoa including Toxoplasma gondii…”
Get more information

A complete shikimate pathway in Toxoplasma gondii: an ancient eukaryotic innovation by Campbell, S.A., Richards, T.A., Mui, E.J., Samuel, B.U., Coggins, J.R., McLeod, R., Roberts, C.W.

“…The shikimate pathway is essential for survival of the apicomplexan parasites Plasmodium falciparum, Toxoplasma gondii and Cryptosporidium parvum. As it is…”
Get full text

Vaccination with Recombinant Leishmania donovani Gamma-Glutamylcysteine Synthetase Fusion Protein Protects Against L. donovani Infection by Henriquez, F. L, Campbell, S. A, Roberts, C. W, Mullen, A. B, Burchmore, R, Carter, K. C

“…Visceral leishmaniasis presents a serious health threat in many parts of the world. There is, therefore, an urgent need for an approved vaccine for clinical…”
Get full text

Immunological Studies of Chronic Ocular Toxoplasmosis: Up-Regulation of Major Histocompatibility Complex Class I and Transforming Growth Factor β and a Protective Role for Interleukin-6 by LYONS, R. E, ANTHONY, J. P, FERGUSON, D. J. P, BYRNE, N, ALEXANDER, J, ROBERTS, F, ROBERTS, C. W

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Coronary artery calcification: assessment with electron beam CT and histomorphometric correlation by Mautner, G C, Mautner, S L, Froehlich, J, Feuerstein, I M, Proschan, M A, Roberts, W C, Doppman, J L

“…To assess the reliability of electron beam computed tomography (CT) in the detection of calcific deposits in coronary arteries. The authors quantitatively…”
Get more information

Type I and type II fatty acid biosynthesis in Eimeria tenella: enoyl reductase activity and structure by Lu, J Z, Muench, S P, Allary, M, Campbell, S, Roberts, C W, Mui, E, McLeod, R L, Rice, D W, Prigge, S T

“…Apicomplexan parasites of the genus Eimeria are the major causative agent of avian coccidiosis, leading to high economic losses in the poultry industry. Recent…”
Get more information

DNA vaccination against the parasite enzyme gamma-glutamylcysteine synthetase confers protection against Leishmania donovani infection by Carter, K.C, Henriquez, F.L, Campbell, S.A, Roberts, C.W, Nok, A, Mullen, A.B, McFarlane, E

“…Abstract In this study the potential of using Leishmania donovani gamma-glutamylcysteine synthetase (glutamate-cysteine ligase, γ-GCS) as a rational target for…”
Get full text

Enzymes of type II fatty acid synthesis and apicoplast differentiation and division in Eimeria tenella by Ferguson, D.J.P., Campbell, S.A., Henriquez, F.L., Phan, L., Mui, E., Richards, T.A., Muench, S.P., Allary, M., Lu, J.Z., Prigge, S.T., Tomley, F., Shirley, M.W., Rice, D.W., McLeod, R., Roberts, C.W.

“…Apicomplexan parasites, Eimeria tenella, Plasmodium spp. and Toxoplasma gondii, possess a homologous plastid-like organelle termed the apicoplast, derived from…”
Get full text