Search Results - "Roberto, Ciccocioppo"
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N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats
Published in Psychopharmacology (01-01-2021)“…Rationale N-acylethanolamine acid amidase (NAAA) is an intracellular cysteine hydrolase that terminates the biological actions of oleoylethanolamide (OEA) and…”
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Activation of peroxisome proliferator-activated receptor γ reduces alcohol drinking and seeking by modulating multiple mesocorticolimbic regions in rats
Published in Neuropsychopharmacology (New York, N.Y.) (01-01-2021)“…Peroxisome proliferator-activated receptor γ (PPARγ) is an intracellular transcription factor whose signaling activation by the selective agonist pioglitazone…”
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NOP receptor antagonism attenuates reinstatement of alcohol-seeking through modulation of the mesolimbic circuitry in male and female alcohol-preferring rats
Published in Neuropsychopharmacology (New York, N.Y.) (01-11-2021)“…In patients suffering from alcohol use disorder (AUD), stress and environmental stimuli associated with alcohol availability are important triggers of relapse…”
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Effect of Glucocorticoid Receptor Antagonism on Alcohol Self-Administration in Genetically-Selected Marchigian Sardinian Alcohol-Preferring and Non-Preferring Wistar Rats
Published in International journal of molecular sciences (17-04-2021)“…Alcoholism is a chronically relapsing disorder characterized by high alcohol intake and a negative emotional state during abstinence, which contributes to…”
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Role of Nociceptin/Orphanin FQ-NOP Receptor System in the Regulation of Stress-Related Disorders
Published in International journal of molecular sciences (30-11-2021)“…Nociceptin/orphanin FQ (N/OFQ) is a 17-residue neuropeptide that binds the nociceptin opioid-like receptor (NOP). N/OFQ exhibits nucleotidic and aminoacidics…”
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NOP-Related Mechanisms in Substance Use Disorders
Published in Handbook of experimental pharmacology (01-01-2019)“…Nociceptin/orphanin FQ (N/OFQ) is a 17 amino acid peptide that was deorphanized in 1995 and has been widely studied since. The role of the N/OFQ system in drug…”
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Further evidence for the involvement of the PPARγ system on alcohol intake and sensitivity in rodents
Published in Psychopharmacology (01-10-2020)“…Rationale Peroxisome Proliferator Activator receptors (PPARs) are intracellular receptors that function as transcription factors, which regulate specific…”
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Dysregulation of Nociceptin/Orphanin FQ and Dynorphin Systems in the Extended Amygdala of Alcohol Preferring Marchigian Sardinian (msP) Rats
Published in International journal of molecular sciences (28-02-2021)“…Previous studies have shown that genetically selected Marchigian Sardinian alcohol-preferring (msP) rats consume excessive amounts of ethanol to self-medicate…”
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Role of orexin-1 receptor mechanisms on compulsive food consumption in a model of binge eating in female rats
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2012)“…Orexins (OX) and their receptors (OXR) modulate feeding, arousal, stress, and drug abuse. Neural systems that motivate and reinforce drug abuse may also…”
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Reduced limbic metabolism and fronto-cortical volume in rats vulnerable to alcohol addiction
Published in NeuroImage (Orlando, Fla.) (01-04-2013)“…Alcohol abuse is associated with long-term reductions in fronto-cortical volume and limbic metabolism. However, an unanswered question in alcohol research is…”
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Cocaine-predictive stimulus induces drug-seeking behavior and neural activation in limbic brain regions after multiple months of abstinence: Reversal by D1 antagonists
Published in Proceedings of the National Academy of Sciences - PNAS (13-02-2001)“…The conditioning of cocaine's subjective actions with environmental stimuli may be a critical factor in long-lasting relapse risk associated with cocaine…”
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CHARACTERIZATION OF AXONAL DEGENERATION IN ALCOHOL USE DISORDER: PRECLINICAL STUDY
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Palmitoleoylethanolamide Is an Efficient Anti-Obesity Endogenous Compound: Comparison with Oleylethanolamide in Diet-Induced Obesity
Published in Nutrients (28-07-2021)“…Obesity is currently a major epidemic in the developed world. However, we lack a wide range of effective pharmacological treatments and therapies against…”
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Communal nesting differentially attenuates the impact of pre-weaning social isolation on behavior in male and female rats during adolescence and adulthood
Published in Frontiers in behavioral neuroscience (17-10-2023)“…Early social isolation (ESI) disrupts neurodevelopmental processes, potentially leading to longlasting emotional and cognitive changes in adulthood. Communal…”
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Glucocorticoid Receptor Antagonist Mifepristone Does Not Alter Innate Anxiety-Like Behavior in Genetically-Selected Marchigian Sardinian (msP) Rats
Published in International journal of molecular sciences (18-03-2021)“…Marchigian Sardinian alcohol-preferring (msP) rats serve as a unique model of heightened alcohol preference and anxiety disorders. Their innate enhanced stress…”
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Outcomes of early social experiences on glucocorticoid and endocannabinoid systems in the prefrontal cortex of male and female adolescent rats
Published in Frontiers in cellular neuroscience (20-12-2023)“…Social and emotional experiences differently shape individual's neurodevelopment inducing substantial changes in neurobiological substrates and behavior,…”
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Pharmacological and Behavioral Effects of the Synthetic Cannabinoid AKB48 in Rats
Published in Frontiers in neuroscience (30-10-2019)“…AKB48 is a synthetic cannabinoid belonging to a structural class with an indazole core structure, illegally marketed as incense, herbal preparations, or…”
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Cebranopadol, a Mixed Opioid Agonist, Reduces Cocaine Self-administration through Nociceptin Opioid and Mu Opioid Receptors
Published in Frontiers in psychiatry (13-11-2017)“…Cocaine addiction is a widespread psychiatric condition still waiting for approved efficacious medications. Previous studies suggested that simultaneous…”
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Administration of Linoleoylethanolamide Reduced Weight Gain, Dyslipidemia, and Inflammation Associated with High-Fat-Diet-Induced Obesity
Published in Nutrients (01-10-2023)“…Acylethanolamides (NAEs) are bioactive lipids derived from diet fatty acids that modulate important homeostatic functions, including appetite, fatty acid…”
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