Search Results - "Robert W. Veltri"
-
1
EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance
Published in Cell (12-09-2013)“…Cell surface growth factor receptors couple environmental cues to the regulation of cytoplasmic homeostatic processes, including autophagy, and aberrant…”
Get full text
Journal Article -
2
Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer
Published in Cancer research (Chicago, Ill.) (01-01-2009)“…Suppression of androgen production and function provides palliation but not cure in men with prostate cancer (PCa). Therapeutic failure and progression to…”
Get full text
Journal Article -
3
Macrophage inhibitory cytokine 1 biomarker serum immunoassay in combination with PSA is a more specific diagnostic tool for detection of prostate cancer
Published in PloS one (08-04-2015)“…Prostate cancer (PCa) is the most common malignancy among men in the United States. Though highly sensitive, the often-used prostate-specific antigen (PSA)…”
Get full text
Journal Article -
4
Immunohistochemical differentiation of high-grade prostate carcinoma from urothelial carcinoma
Published in The American journal of surgical pathology (01-08-2007)“…The histologic distinction between high-grade prostate cancer and infiltrating high-grade urothelial cancer may be difficult, and has significant implications…”
Get full text
Journal Article -
5
Hypermethylation of genes detected in urine from Ghanaian adults with bladder pathology associated with Schistosoma haematobium infection
Published in PloS one (18-03-2013)“…Schistosoma haematobium is associated with chronic bladder damage and may subsequently induce bladder cancer in humans, thus posing a serious threat where the…”
Get full text
Journal Article -
6
Extended peripheral zone biopsy schemes increase cancer detection rates and minimize variance in prostate specific antigen and age related cancer rates: results of a community multi-practice study
Published in The Journal of urology (01-01-2003)“…We assessed the impact of age and prostate specific antigen (PSA) on extended systematic biopsy schemes for detecting prostate carcinoma and better…”
Get more information
Journal Article -
7
ProPSA and Diagnostic Biopsy Tissue DNA Content Combination Improves Accuracy to Predict Need for Prostate Cancer Treatment Among Men Enrolled in an Active Surveillance Program
Published in Urology (Ridgewood, N.J.) (01-03-2011)“…Objectives To assess a novel application of the Prostate Health Index (phi) and biopsy tissue DNA content in benign-adjacent and cancer areas to predict which…”
Get full text
Journal Article -
8
Pro–Prostate-Specific Antigen Measurements in Serum and Tissue Are Associated with Treatment Necessity among Men Enrolled in Expectant Management for Prostate Cancer
Published in Clinical cancer research (01-12-2009)“…Purpose: We assessed the association of quantitative clinical and pathologic information, including serum and tissue pro–prostate-specific antigen (proPSA)…”
Get full text
Journal Article -
9
The Upregulation of PI3K/Akt and MAP Kinase Pathways is Associated with Resistance of Microtubule-Targeting Drugs in Prostate Cancer
Published in Journal of cellular biochemistry (01-07-2015)“…ABSTRACT Resistance is a significant limitation to the effectiveness of cancer therapies. The PI3K/Akt and MAP kinase pathways play important roles in a…”
Get full text
Journal Article -
10
Valproic acid causes dose- and time-dependent changes in nuclear structure in prostate cancer cells in vitro and in vivo
Published in Molecular cancer therapeutics (01-04-2009)“…Histone deacetylase inhibitors such as valproic acid (VPA) are promising anticancer agents that change the acetylation status of histones and loosen the…”
Get full text
Journal Article -
11
Analysis of repeated biopsy results within 1 year after a noncancer diagnosis
Published in Urology (Ridgewood, N.J.) (01-04-2000)“…Objectives. A prostate biopsy data base derived from patients referred to private practice urologists was analyzed for the cancer diagnosis rates of the…”
Get full text
Journal Article -
12
Serum marker %[‐2]proPSA and the Prostate Health Index improve diagnostic accuracy for clinically relevant prostate cancer
Published in BJU international (01-01-2016)Get full text
Journal Article -
13
Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity
Published in Proceedings of the National Academy of Sciences - PNAS (28-03-2017)“…Intrinsically disordered proteins (IDPs) that lack a unique 3D structure and comprise a large fraction of the human proteome play important roles in numerous…”
Get full text
Journal Article -
14
Advances in the computational and molecular understanding of the prostate cancer cell nucleus
Published in Journal of cellular biochemistry (01-09-2018)“…Nuclear alterations are a hallmark of many types of cancers, including prostate cancer (PCa). Recent evidence shows that subvisual changes, ones that may not…”
Get full text
Journal Article -
15
Prediction of Prostate-Specific Antigen Recurrence in Men with Long-term Follow-up Postprostatectomy Using Quantitative Nuclear Morphometry
Published in Cancer epidemiology, biomarkers & prevention (01-01-2008)“…Background: Nuclear morphometric signatures can be calculated using nuclear size, shape, DNA content, and chromatin texture descriptors [nuclear morphometric…”
Get full text
Journal Article -
16
Gleason score 6 adenocarcinoma: should it be labeled as cancer?
Published in Journal of clinical oncology (10-12-2012)Get full text
Journal Article -
17
Nuclear morphometry, nucleomics and prostate cancer progression
Published in Asian journal of andrology (01-05-2012)Get full text
Journal Article -
18
Nuclear Shape and Architecture in Benign Fields Predict Biochemical Recurrence in Prostate Cancer Patients Following Radical Prostatectomy: Preliminary Findings
Published in European urology focus (01-10-2017)“…Abstract Background Gleason scoring represents the standard for diagnosis of prostate cancer (PCa) and assessment of prognosis following radical prostatectomy…”
Get full text
Journal Article -
19
Ability to Predict Metastasis Based On Pathology Findings and Alterations in Nuclear Structure Of Normal-Appearing and Cancer Peripheral Zone Epithelium in the Prostate
Published in Clinical cancer research (15-05-2004)“…Purpose: Malignant transformation in the prostate produces significant alterations in glandular architecture (Gleason grade) and nuclear structure that provide…”
Get full text
Journal Article -
20
Effect of Testosterone Replacement Therapy on Prostate Tissue in Men With Late-Onset Hypogonadism: A Randomized Controlled Trial
Published in JAMA : the journal of the American Medical Association (15-11-2006)“…CONTEXT Prostate safety is a primary concern when aging men receive testosterone replacement therapy (TRT), but little information is available regarding the…”
Get full text
Journal Article