Search Results - "Robert L. Murphy"
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Effect of cervical cancer education and provider recommendation for screening on screening rates: A systematic review and meta-analysis
Published in PloS one (05-09-2017)“…Although cervical cancer is largely preventable through screening, detection and treatment of precancerous abnormalities, it remains one of the top causes of…”
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Incident Kaposi sarcoma during the expansion of antiretroviral therapy eligibility in Nigeria: a retrospective cohort study
Published in BMC cancer (21-09-2023)“…Abstract Introduction The expansion of antiretroviral therapy (ART) eligibility could lead to earlier initiation of Human Immunodeficiency Virus (HIV)…”
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3
Abacavir/Lamivudine Versus Tenofovir DF/Emtricitabine as Part of Combination Regimens for Initial Treatment of HIV: Final Results
Published in The Journal of infectious diseases (15-10-2011)“…Background. AIDS Clinical Trials Group A5202 compared blinded abacavir/lamivudine (ABC/3TC) to tenofovir DF/emtricitabine (TDF/FTC) with efavirenz (EFV) or…”
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4
The need for more holistic immune profiling in next-generation SARS-CoV-2 vaccine trials
Published in Frontiers in immunology (20-09-2022)“…First-generation anit-SARS-CoV-2 vaccines were highly successful. They rapidly met an unforeseen emergency need, saved millions of lives, and simultaneously…”
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Clinical evaluation of the Diagnostic Analyzer for Selective Hybridization (DASH): A point-of-care PCR test for rapid detection of SARS-CoV-2 infection
Published in PloS one (16-06-2022)“…An ideal test for COVID-19 would combine the sensitivity of laboratory-based PCR with the speed and ease of use of point-of-care (POC) or home-based rapid…”
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Safety, Tolerability, and Mechanisms of Antiretroviral Activity of Pegylated Interferon Alfa-2a in HIV-1- Monoinfected Participants: A Phase II Clinical Trial
Published in The Journal of infectious diseases (01-06-2010)“…Background. To our knowledge, the antiviral activity of pegylated interferon alfa-2a has not been studied in participants with untreated human immunodeficiency…”
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Clinical risk factors associated with multidrug-resistant tuberculosis (MDR-TB) in Mali
Published in International journal of infectious diseases (01-04-2019)“…•MDR-TB was associated with younger age in Mali.•HIV was not a risk factor for MDR-TB.•MDR-TB did alter the patient’s physical condition compared to…”
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Community cervical cancer screening and precancer risk in women living with HIV in Jos Nigeria
Published in BMC public health (16-01-2024)“…High HIV prevalence, and lack of organized screening for the indigent population receiving care and treatment within HIV clinics in low-resource settings…”
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Vaginal microbiome community state types and high-risk human papillomaviruses in cervical precancer and cancer in North-central Nigeria
Published in BMC cancer (20-07-2023)“…High risk human papillomaviruses (HR-HPV) have a causal role in cervical oncogenesis, and HIV-mediated immune suppression allows HR-HPV to persist. We studied…”
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10
Hepatocellular carcinoma presentation and prognosis among Nigerian adults with and without HIV
Published in PloS one (06-03-2023)“…Hepatocellular carcinoma (HCC) is an increasing cause of mortality in Nigeria among persons with HIV (PLH), as access to antiretroviral therapy (ART) improves…”
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Integrated antibody and cellular immunity monitoring are required for assessment of the long term protection that will be essential for effective next generation vaccine development
Published in Frontiers in immunology (2023)“…The COVID pandemic exposed the critical role T cells play in initial immunity, the establishment and maintenance of long term protection, and of durable…”
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12
p.Arg72Pro polymorphism of P53 and breast cancer risk: a meta-analysis of case-control studies
Published in BMC medical genetics (19-10-2020)“…The effect of the p.Arg72Pro variant of the P53 gene on the risk of development ofbreast cancer remains variable in populations. However, the use ofstrategies…”
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Mycobacterium africanum (Lineage 6) shows slower sputum smear conversion on tuberculosis treatment than Mycobacterium tuberculosis (Lineage 4) in Bamako, Mali
Published in PloS one (12-12-2018)“…Ancestral M. tuberculosis complex lineages such as M. africanum are underrepresented among retreatment patients and those with drug resistance. To test the…”
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14
Development and clinical evaluation of a new multiplex PCR assay for a simultaneous diagnosis of tuberculous and nontuberculous mycobacteria
Published in EBioMedicine (01-08-2021)“…The prevalence of non-tuberculous mycobacteria (NTM) has been increasing worldwide in both developed and developing countries. NTM infection is clinically…”
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Achieving a robust mentoring and research capacity program in a LMIC - the BRAINS faculty development model
Published in BMC medical education (20-07-2023)“…A research and training program (RTP) was carried out to build the capacity of faculty and improve the culture of research in the College of Medicine,…”
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Has Omicron Changed the Evolution of the Pandemic?
Published in JMIR public health and surveillance (31-01-2022)“…Variants of the SARS-CoV-2 virus carry differential risks to public health. The Omicron (B.1.1.529) variant, first identified in Botswana on November 11, 2021,…”
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Antituberculosis Therapy and Gut Microbiota: Review of Potential Host Microbiota Directed-Therapies
Published in Frontiers in cellular and infection microbiology (07-12-2021)“…Tuberculosis (TB) remains a major public health concern with millions of deaths every year. The overlap with HIV infections, long treatment duration, and the…”
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Molecular epidemiology and genetic diversity of Mycobacterium tuberculosis complex in referral health centers of Bamako, Mali: What is new?
Published in International journal of infectious diseases (01-04-2022)“…Tuberculosis (TB) remains an important global health issue worldwide. Despite this scourge threatening many human lives, especially in developing countries,…”
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DNA methylation of individual repetitive elements in hepatitis C virus infection-induced hepatocellular carcinoma
Published in Clinical epigenetics (21-10-2019)“…The two most common repetitive elements (REs) in humans, long interspersed nuclear element-1 (LINE-1) and Alu element (Alu), have been linked to various…”
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Prevalence of HIV-1 Natural Polymorphisms and Integrase-Resistance-Associated Mutations in African Children
Published in Viruses (01-02-2023)“…Integrase inhibitors (INIs) are a potent option for HIV treatment. Limited data exist on INI resistance in West Africa, particularly in children living with…”
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