Search Results - "Robert Bray, Mark"

P471: POLO‐LIKE KINASE 4 INHIBITION INDUCED ANTI‐LEUKAEMIC EFFECTS THROUGH HISTONE MODIFICATION IN TP53 MUTATED ACUTE MYELOID LEUKAEMIA by Lam, Wing, Dang, Kenny, Him Man, Cheuk, Zeng, Xiao‐Yuan, Zheng, Lichuan, Ka‐Lam Ng, Nelson, Chan, Koon‐Chuen, Kwok, Tsz‐Ho, Chi‐Chun Ng, Timothy, Leung, Wing‐Yan, Shing‐Yan Huen, Michael, Chak‐Lui Wong, Carmen, Wai Eric So, Chi, Dou, Zhixun, Robert Bray, Mark, Mak, Tak, Yh Leung, Anskar

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CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma by Chan, Cerise Yuen-Ki, Chiu, David Kung-Chun, Yuen, Vincent Wai-Hin, Law, Cheuk-Ting, Wong, Bowie Po-Yee, Thu, Kelsie Lynn, Cescon, David Ward, Soria-Bretones, Isabel, Cheu, Jacinth Wing-Sum, Lee, Derek, Tse, Aki Pui-Wah, Zhang, Misty Shuo, Tan, Kel Vin, Ng, Irene Oi-Lin, Khong, Pek-Lan, Yau, Thomas Chung-Cheung, Bray, Mark Robert, Mak, Tak Wah, Wong, Carmen Chak-Lui

“…Deregulation of cell cycle is a typical feature of cancer cells. Normal cells rely on the strictly coordinated spindle assembly checkpoint (SAC) to maintain…”
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Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML by Man, Cheuk-Him, Lam, Wing, Dang, Chee-Chean, Zeng, Xiao-Yuan, Zheng, Li-Chuan, Chan, Natalie Nok-Man, Ng, Ka-Lam, Chan, Koon-Chuen, Kwok, Tsz-Ho, Ng, Timothy Chi-Chun, Leung, Wing-Yan, Huen, Michael Shing-Yan, Wong, Carmen Chak-Lui, So, Chi Wai Eric, Dou, Zhixun, Goyama, Susumu, Bray, Mark Robert, Mak, Tak Wah, Leung, Anskar Yu-Hung

“…Acute myeloid leukemia (AML) with TP53 mutation is one of the most lethal cancers and portends an extremely poor prognosis. Based on in silico analyses of…”
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